{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:48:17Z","timestamp":1769906897643,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Most published reports of COVID\u201019 Intensive Care Unit (ICU) patients are from large tertiary hospitals and often present short\u2010term or incomplete outcome data. There are reports indicating that ICUs with fewer beds are associated with higher mortality. This study aimed to investigate the definitive outcome and patient characteristics of the complete first wave of COVID\u201019 patients admitted to ICU in a secondary hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this prospective observational study, all patients with respiratory failure and a positive SARS\u2010CoV\u20102 test admitted to V\u00e4ster\u00e5s Hospital ICU between 24 March and July 22, 2020 were included. The primary outcome was defined as 90\u2010day mortality. Secondary outcomes included ICU length of stay, hospital length of stay, number of days with invasive ventilation, need for vasopressors\/inotropes, and use of renal replacement therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010three patients were included. Median age (range) was 59 (33\u201076) and 74% were men. Obesity and hypertension were the most common comorbidities and 45% of the patients were born outside Europe. Ninety\u2010day mortality was 30%. Median ICU length of stay (interquartile range) was 14 (5\u201024) days and the duration of invasive mechanical ventilation 16 (12\u201026) days. No patients received dialysis at 90\u2010day follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this cohort of COVID\u201019 patients treated in a secondary hospital ICU, mortality rates were low compared to early studies from China, Italy, and the United States, but similar to other government\u2010funded hospitals in Scandinavia. A preparatory reorganization enabled an increase in ICU capacity, hence avoiding an overwhelmed intensive care organization.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.446","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T18:38:51Z","timestamp":1639507131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Characteristics and definitive outcomes of <scp>COVID<\/scp>\u201019 patients admitted to a secondary hospital intensive care unit in Sweden"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5671-2563","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Sj\u00f6str\u00f6m","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care V\u00e4ster\u00e5s Hospital  V\u00e4ster\u00e5s Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emeli","family":"M\u00e5nsson","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, V\u00e4ster\u00e5s Hospital, V\u00e4ster\u00e5s, and School of Medical Sciences, Faculty of Medicine and Health \u00d6rebro University, \u00d6rebro, and Region V\u00e4stmanland\u2014Uppsala University, Centre for Clinical Research, V\u00e4ster\u00e5s Hospital  V\u00e4ster\u00e5s Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefin","family":"Viklund Kamienny","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology V\u00e4ster\u00e5s Hospital  V\u00e4ster\u00e5s Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erland","family":"\u00d6stberg","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care V\u00e4ster\u00e5s Hospital, V\u00e4ster\u00e5s, and Region V\u00e4stmanland\u2014Uppsala University, Centre for Clinical Research, V\u00e4ster\u00e5s Hospital  V\u00e4ster\u00e5s Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15201"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.3539"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0885066620946692"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202003-0736LE"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13694"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1966"},{"key":"e_1_2_11_8_1","unstructured":"COVID\u201019 Map [Internet].Johns Hopkins Coronavirus Resource Center [cited 2020 Dec 10].https:\/\/coronavirus.jhu.edu\/map.html"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000001459"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.3596"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13701"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-02939-x"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13785"},{"key":"e_1_2_11_14_1","unstructured":"Annual reports [Internet]. Swedish Intensive Care Registry [cited 2020 Dec 10].https:\/\/www.icuregswe.org\/data--resultat\/arsrapporter\/"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2627-8"},{"key":"e_1_2_11_16_1","unstructured":"Klorokin och hydroxiklorokin b\u00f6r endast anv\u00e4ndas f\u00f6r behandling av patienter med covid\u201019 inom kliniska studier [Internet]. Swedish Medical Products Agency [cited 2020 Dec 10].https:\/\/www.lakemedelsverket.se\/sv\/nyheter\/klorokin\u2010och\u2010hydroxiklorokin\u2010bor\u2010endast\u2010anvandas\u2010for\u2010behandling\u2010av\u2010patienter\u2010med\u2010covid\u201019\u2010inom\u2010kliniska\u2010studier"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"e_1_2_11_18_1","unstructured":"Riktlinjer f\u00f6r profylax och behandling av ven\u00f6s tromboembolism hos patienter med covid\u201019. Year 2020 [Internet]. Janusinfo. [cited 2021 Feb 16].https:\/\/janusinfo.se\/behandling\/expertgruppsutlatanden\/koagulationssjukdomarochplasmaprodukter\/koagulationssjukdomarochplasmaprodukter\/riktlinjerforprofylaxochbehandlingavvenostromboembolismhospatientermedcovid19.5.735b5f221714e865c978301e.html"},{"issue":"23","key":"e_1_2_11_19_1","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin Definition","volume":"307","author":"ARDS Definition Task Force","year":"2012","journal-title":"JAMA"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00194909"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30079-5"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e32835914d5"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03375-7"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.12270"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa2011686"},{"key":"e_1_2_11_26_1","unstructured":"Swedish and foreign\u2010born population by region age and sex. Year 2019 [Internet]. Statistics Sweden. [cited 2020 Dec 10].http:\/\/www.statistikdatabasen.scb.se\/pxweb\/sv\/ssd\/START__BE__BE0101__BE0101E\/InrUtrFoddaRegAlKon\/?loadedQueryId=83063&timeType=top&timeValue=20"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2521-4"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.446","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.446","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T18:48:58Z","timestamp":1692989338000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1002\/hsr2.446"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.446","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"2021-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e446"}}