{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:09:31Z","timestamp":1788307771183,"version":"build-2803163510"},"reference-count":57,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T00:00:00Z","timestamp":1640044800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Guillain Barr\u00e9 syndrome (GBS) could be triggered by an infectious disease but by vaccination as well. Thus, suffering GBS may influence patients' attitudes towards vaccination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An anonymous questionnaire consisting of the Overall Neuropathy Limitations Score (ONLS), the short form\u201036 health survey (SF\u201036), and questions addressing patients' attitude towards vaccination was sent to members of a German GBS support group and to patients with GBS diagnosis who were treated at Jena University Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010seven questionnaires clearly stated GBS as a diagnosis and were included in the analysis. Although 19.6% of the GBS patients reported having no disability in the long\u2010time follow\u2010up, a considerable number of patients still had persistent neurological symptoms; 74.2% of the GBS patients reported being able to walk at least 10\u2009m independently. However, 5.2% were restricted to wheelchair. The patients reached lower scores in all domains of quality of life compared to German controls. Moreover, patients showed a more critical attitude towards vaccination compared to a German representative survey. Fewer patients (58.8%) received a vaccination after suffering from GBS than before (77.3%). Every tenth patient believed that vaccination was the trigger for the GBS. 32% of the patients did not receive a vaccination in the last 5\u2009years mainly because of the fear of adverse effects (32%) or disadvise of the general practitioners (25.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Although the risk of relapse following immunization may be rather low, uncertainties and fears still impair the counseling of these patients by their medical practitioner.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.469","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T17:55:02Z","timestamp":1640109302000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Patients' attitude towards vaccination after Guillain Barr\u00e9 syndrome"],"prefix":"10.1002","volume":"4","author":[{"given":"Ben\u2010Ole","family":"Holtz","sequence":"first","affiliation":[{"name":"Department of Neurology Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8615-5040","authenticated-orcid":false,"given":"Alexander","family":"Grimm","sequence":"additional","affiliation":[{"name":"Department of Neurology Tuebingen University Hospital  Tuebingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3191-2796","authenticated-orcid":false,"given":"Hubertus","family":"Axer","sequence":"additional","affiliation":[{"name":"Department of Neurology Jena University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00517-1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1693005"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0250-9"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000184748"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007719"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-015-1365-7"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.121"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30221-0"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000741"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2009191"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10515-8"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-09742-2"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1997.tb00214.x"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000237334.69665.92"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000149521.65474.83"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2008.02311.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8020150"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112795"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)62189-8"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2013.301651"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2009.00243.x"},{"key":"e_1_2_12_23_1","volume-title":"Einstellungen, Wissen Und Verhalten von Erwachsenen Und Eltern Gegen\u00fcber Impfungen \u2013 Ergebnisse Der Repr\u00e4sentativbefragung 2018 Zum Infektionsschutz. 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