{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:21:22Z","timestamp":1755217282415,"version":"3.43.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T00:00:00Z","timestamp":1724112000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Blood, vital for transporting nutrients and maintaining balance, comprises red blood cells, white blood cells, and platelets, each pivotal. Imbalances lead to issues\u2014low red cells cause fatigue (anemia), high white cells hint at infection, low counts raise infection risks. Using trendy statistical approaches, investigating the complex link between platelet counts and numerous blood components. Our investigation, leveraging count regression approaches, revealed deep insights into the interaction between platelet counts and other important hematological markers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study utilized data from 3120 individuals, including both male and female participants, who visited these hospitals between June 16, 2022 and December 17, 2022, to assess their blood samples through testing by using convenience non\u2010parametric sampling framework. Platelet count was taken into account as a measure of outcome in this research. This specific study region was chosen for its easy accessibility, which helped the seamless execution of the data\u2010gathering technique. Count regression, negative binomial regression, and quasi\u2010Poisson regression techniques have been employed for examining relationship of the data sets.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three different count regression models were utilized to assess the proper association between the response and the relevant covariates and we found negative binomial count regression model (Akaike information criterion\u2009=\u200976.55, Bayesian information criterion\u2009=\u200976.59, and deviance\u2009=\u20093.14) was providing comparatively better performance than others. Based on the chosen model we found white blood cell, erythrocyte sedimentation rate, and eosinophils are significant but neutrophil, monocyte, and lymphocyte are not significant. We have also gone through proper model adequacy checking for our selected model and we found enough evidence to justify our model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>From the result, we found insightful remarks into the mechanisms involved in platelet production and regulation, which can aid in developing increased effective treatments and interventions to maintain optimal platelet levels and prevent health problems related to abnormal platelet counts.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.70007","type":"journal-article","created":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T22:10:10Z","timestamp":1724278210000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exploring the relationship between blood platelet and other components utilizing count regression: A cross\u2010sectional study in Bangladesh"],"prefix":"10.1002","volume":"7","author":[{"given":"Umme","family":"Honey","sequence":"first","affiliation":[{"name":"Department of Statistics and Data Science Jahangirnagar University Dhaka Savar Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SM Arif Bin","family":"Saleh","sequence":"additional","affiliation":[{"name":"NYU Langone Health Long Island New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7088-8947","authenticated-orcid":false,"given":"Md. Sifat Ar","family":"Salan","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science Jahangirnagar University Dhaka Savar Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Alamgir","family":"Kabir","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science Jahangirnagar University Dhaka Savar Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akher","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science Jahangirnagar University Dhaka Savar Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,20]]},"reference":[{"volume-title":"Clinical Hematology and Fundamentals of Hemostasis","year":"2024","author":"Harmening D","key":"e_1_2_15_2_1"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114606"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2020.100733"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-022-01685-8"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-024-00881-7"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10040835"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9030808"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.122.321566"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15751"},{"key":"e_1_2_15_11_1","doi-asserted-by":"crossref","unstructured":"RahmanS DasSK FarhanaZ et al. 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