{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:38:13Z","timestamp":1789094293199,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Thoracic spine manipulation (TSM) increases the thoracic spine's range of motion (ROM), effectively reducing pain intensity and disability in patients with mechanical neck pain. We aimed to determine the effect of TSM on neck pain intensity and functional impairment in patients classified under the \u201cmobility\u201d category in Childs' classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this randomized controlled trial, patients with mechanical neck pain who met the inclusion criteria were randomly assigned to either the TSM (<jats:italic>n<\/jats:italic>\u2009=\u200921) or sham manipulation (<jats:italic>n<\/jats:italic>\u2009=\u200920) group. The primary outcomes were pain during neck rotation and subjective improvement assessed using the Numerical Pain Rating Scale (NPRS) and Global Rating of Change (GROC), respectively. The secondary outcomes were NPRS at rest, disability (assessed using the Neck Disability Index [NDI]), and ROM of the cervical and thoracic spine rotation. Outcome measurements were performed at baseline, immediately after treatment, 1 week after treatment, and at the 4\u2010week follow\u2010up. Linear mixed models were used to analyze the NPRS, NDI, and ROM. The GROC was analyzed using a chi\u2010square test for the percentage recording \u2265+4; the means of each group were compared using an unpaired t\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The NPRS with neck rotation, neck and thoracic ROM, and NDI showed significant interactions between the groups. The NPRS with neck rotation was significantly lower in the TSM group than in the sham group at all time points after the treatment (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). There was no difference between the groups in the proportion showing moderate (\u2265+4) improvement according to the GROC; however, there was a significant difference in the mean values (<jats:italic>p<\/jats:italic>\u2009=\u20090.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Incorporating TSM into treatment protocols may improve clinical outcomes in patients with neck pain, potentially leading to better pain management and functional recovery. Therefore, physiotherapists should consider TSM as a viable and effective intervention to improve patient outcomes in neck pain rehabilitation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.70031","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T10:39:56Z","timestamp":1725014396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of thoracic manipulation on neck pain in the mobility group: A randomized controlled trial"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5811-0702","authenticated-orcid":false,"given":"Ryota","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Physical Therapy Tokyo Metropolitan University: 7\u20102\u201010 Higashiogu Arakawa\u2010ku Tokyo Japan"},{"name":"Yomiuri Clinic: 1\u20107\u20101 Otemachi, Chiyoda\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuna","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Tokyo Metropolitan University: 7\u20102\u201010 Higashiogu Arakawa\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiraku","family":"Nagahori","sequence":"additional","affiliation":[{"name":"Seijo Surgery Orthopedic Clinic: 2\u201035\u201018 Seijo Setagaya\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Tazawa","sequence":"additional","affiliation":[{"name":"Sonodakai joint replacement center hospital: 1\u201021\u201010 Hokuima Adachi\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3550-4519","authenticated-orcid":false,"given":"Hironobu","family":"Kuruma","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Tokyo Metropolitan University: 7\u20102\u201010 Higashiogu Arakawa\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04957-4"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204431"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-020-03379-y"},{"key":"e_1_2_12_5_1","unstructured":"LezinN Watkins\u2010CastilloSThe impact of musculoskeletal disorders on Americans\u2010opportunities for action (3rd ed.). Burden of musculoskeletal diseases in the United States: prevalence societal and economic cost;2016. Retrieved fromhttp:\/\/www.boneandjointburden.org\/docs\/BMUSExecutiveSummary2016_0.pdf"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181e9b831"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31816454c8"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39127.608299.80"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2011.04.001"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1179\/2042618612Y.0000000027"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2007.0110"},{"key":"e_1_2_12_12_1","volume-title":"Kinesiology of the Human Body Under Normal and Athological Conditions","author":"Steindler A","year":"1955"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.31616\/asj.2018.0302"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.2340\/165019771997167174"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10669817.2022.2056309"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2019.8150"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1179\/106698108790818530"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2010.08.003"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2024.2316897"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.28.175"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211877"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2009.2914"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S368910"},{"key":"e_1_2_12_24_1","article-title":"Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment","volume":"2015","author":"Gross A","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphys.2020.12.005"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2004.34.11.686"},{"key":"e_1_2_12_26_2","doi-asserted-by":"crossref","unstructured":"discussion697\u2010700doi:10.2519\/jospt.2004.34.11.686","DOI":"10.2519\/jospt.2004.34.11.686"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200209010-00004"},{"key":"e_1_2_12_27_2","doi-asserted-by":"crossref","unstructured":"discussion1843doi:10.1097\/00007632-200209010-00004","DOI":"10.1097\/00007632-200209010-00004"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2009.05.004"},{"key":"e_1_2_12_29_1","volume-title":"Manual Mobilization of the Joints, Volume II: The Spine","author":"Kaltenborn FM","year":"2012"},{"key":"e_1_2_12_30_1","volume-title":"Manual of Physical Therapy","author":"Olson KA","year":"2020"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-033909"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e318267f7f5"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-6-59"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ptsp.2018.04.012"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.14474\/ptrs.2017.6.2.65"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-47.1.52"},{"key":"e_1_2_12_37_1","article-title":"Intra\u2010 and inter\u2010rater reliability of the Lumbar\u2010Locked thoracic rotation test in patients with neck pain","volume":"6","author":"Yoshida R","year":"2024","journal-title":"Cureus"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.36.95"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.08.126"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1529-9430(02)00400-X"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2017.0604"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/10669817.2023.2285196"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-39839-3"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20080283"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20060192"},{"key":"e_1_2_12_46_1","first-page":"252","article-title":"Thoracic rotation measurement techniques: clinical commentary","volume":"5","author":"Johnson KD","year":"2010","journal-title":"North Am J Sports Phys Ther"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2018.7738"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.70031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T12:32:31Z","timestamp":1729773151000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.70031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,30]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/hsr2.70031"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.70031","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,30]]},"assertion":[{"value":"2024-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70031"}}