{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T22:47:05Z","timestamp":1791499625304,"version":"4.3.4"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>In the past decade, unmanned aerial systems (UASs), commonly known as drones, have found applications not only in military and agriculture but also in the transportation of medical supplies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The present study was conducted to assess the practicality of utilizing drones as a mode for the delivery of vaccines to combat the challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>An exploratory study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>\n                      Due to the COVID\u201019 pandemic restrictions and paucity of availability of rules and regulations related to drones in India in 2021, this study was conducted as a exploratory study for which number of regulatory approvals are obtained and it involves five drone missions within the premises of the Indian Institute of Technology (IIT), Kanpur, India on a confined airstrip of 3\u2009km\n                      <jats:sup>2<\/jats:sup>\n                      to transport simulated vaccine vials using a multi\u2010rotor top\u2010load UAS in the normal weather conditions in daylight where dummy vaccine vials (COVID\u201019) were packed with cool packs to maintain the temperature. Study was conducted to explore feasibility to carry vaccines through drones and any environmental impact on the vaccine vials while its transportation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The drones demonstrated a maximum flight endurance of 31\u2009min while carrying a payload of up to 4.5\u2009Kg, covering an aerial distance of 17\u2009km at an average speed ranging at 12\u2009m per second. Notably, the vaccine carrier box was able to maintain a recommended temperature of 3\u00b0C\u20134\u00b0C throughout the transportation process, and there is no impact of vibration on the physical integrity and leakage of the vaccine vials during flight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings signify the potential for the drone\u2010based medical supply deliveries across confined and controlled environment conditions. This study provides the insights that there is no environmental impact such as humidity, temperature, wind etc on the drone and no impact on vibrations on the physical integrity and leakage of the dummy vaccine vials. There were few regulatory barriers that required special approvals from concerned authorities. The study was not designed to assess for cost\u2010effectiveness, also it was conducted in defined geography so all sorties were VLOS. Study has various limitations such as using simulated vaccine vials, regulatory barriers, operational barriers etc. Conducting the study in a controlled environment at IIT Kanpur limits generalizability. In spite of these limitations this study provides valuable insights and may explore a diverse environment that can help in strengthening health services especially in difficult terrains.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70208","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T05:57:01Z","timestamp":1736229421000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Assessing the Feasibility of Drone\u2010Mediated Vaccine Delivery: An Exploratory Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0652-1611","authenticated-orcid":false,"given":"Sumit","family":"Aggarwal","sequence":"first","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7251-0355","authenticated-orcid":false,"given":"Prakamya","family":"Gupta","sequence":"additional","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3223-7910","authenticated-orcid":false,"given":"Sivaraman","family":"Balaji","sequence":"additional","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6744-5846","authenticated-orcid":false,"given":"Saurabh","family":"Sharma","sequence":"additional","affiliation":[{"name":"Division of Delivery Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2483-1188","authenticated-orcid":false,"given":"Ajoy Kanti","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Aerospace Engineering IIT Kanpur Kanpur Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4655-8176","authenticated-orcid":false,"family":"Simmy","sequence":"additional","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balram","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5077-6275","authenticated-orcid":false,"given":"Samiran","family":"Panda","sequence":"additional","affiliation":[{"name":"Division of Descriptive Research Indian Council of Medical Research\u2010Headquarters New Delhi Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.06.022"},{"issue":"10","key":"e_1_2_11_3_1","first-page":"1273","article-title":"The Use of UAV\/Drones in the Optimization of Nigeria Vaccine Supply Chain","volume":"10","author":"Michael O. 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