{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:58:12Z","timestamp":1788933492037,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Remnants of laundry detergent ingredients are suspected to be in constant contact with the skin. Allergy sufferers need assurance that the chemicals in everyday products do not cause such disruption. The purpose of this study was to evaluate the effects and tolerability of common laundry detergents on the skin microbiome in individuals with atopic dermatitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two laundry detergents for sensitive skin were tested on subjects with atopic dermatitis by having to wear detergent\u2010washed socks for 7 days. The bacterial population from volunteers\u2019 skin swabs was determined and bacterial viability and biodiversity was evaluated before and after wearing the detergent\u2010washed socks. The tolerability and effect on atopic dermatitis was also evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed that the tested laundry detergents did not have a negative effect on bacterial viability or biodiversity on the skin after being exposed to the detergent\u2010washed socks for a week. The laundry detergents were rated as very good on the tolerability scale and no worsening of skin itch was reported with the use of either detergent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of the study showed that both laundry detergents are skin and allergy friendly and do not alter the skin microbiome.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.70261","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T05:40:18Z","timestamp":1734500418000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluating the Impact of Laundry Detergents on the Skin Microbiome of Atopic Dermatitis Patients\u2014A Clinical Study"],"prefix":"10.1002","volume":"7","author":[{"given":"Demetrios","family":"Christou","sequence":"first","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Stevanovic","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Evers","sequence":"additional","affiliation":[{"name":"Corporate Microbiology, Henkel AG &amp; Co. KGaA D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Weide","sequence":"additional","affiliation":[{"name":"Microbiology &amp; Hygiene, Henkel Consumer Brands, Henkel AG &amp; Co. KGaA D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1466-8875","authenticated-orcid":false,"given":"Torsten","family":"Zuberbier","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.02.031"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268651"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00695-20"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2021.11.001"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.15698\/mic2019.07.682"},{"key":"e_1_2_11_7_1","first-page":"149","article-title":"Single\u2010Strand Conformational Polymorphism Analysis: Basic Principles and Routine Practice","volume":"108","author":"Dong Y.","year":"2005","journal-title":"Methods in Molecular Medicine"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08112.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8040444"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.157"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2023.2212095"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18849"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.16763"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.70261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T07:29:06Z","timestamp":1745566146000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.70261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":12,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/hsr2.70261"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.70261","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2023-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70261"}}