{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T01:22:02Z","timestamp":1775870522270,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Intradialytic hypotension (IDH) is a common phenomenon during hemodialysis (HD), with profound complications and all\u2010cause mortality. Data on IHD is scarce in Sub\u2010Saharan Africa. The study aimed to evaluate the incidence, risk factors, and outcome associated with recurrent IDH among patients on maintenance HD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cohort study conducted at the Kilimanjaro Christian Medical Centre HD unit between August 1, 2021 and July 31, 2022. In the study, 39 met the inclusion criteria, and a total of 4706 HD sessions were analyzed. The predictor was the occurrence of recurrent IDH. The outcomes were mortality from IDH, hospital admission due to IDH, and termination of the respective HD session. Descriptive statistics for categorical and continuous variables. A <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup> test was used to identify associations, and the receiver operating characteristics curve was used to determine the cutoff threshold for different parameters in determining risk factors for recurrent IDH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of IDH was 4.35%; 46.3% of these IDH episodes were recurrent. Risk of IDH was higher in patients with pre\u2010dialytic serum inorganic phosphate levels &gt;\u20091.8\u2009mmol\/L (RR: 2.33, 95% CI: 1.02\u20135.35, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) with a predicted threshold of 1.27\u2009mmol\/L by ROC curve (AUC 0.618, CI: 0.541\u20130.694, sensitivity 60%, specificity 40%), among males (aRR: 9.65, CI: 2.27\u201340.85, <jats:italic>p\u2009=<\/jats:italic>\u20090.002). A systolic blood pressure of &lt;\u2009140\u2009mmHg had a significant protective effect (aRR: 0.34, CI: 0.17\u20130.69, <jats:italic>p\u2009=<\/jats:italic>\u20090.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Recurrent IDH is more common in males, among patients with hyperphosphatemia, and shows seasonal variations. Systolic blood pressure of &lt;\u2009140\u2009mmHg confers a protective effect against recurrent IDH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.70661","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T14:27:56Z","timestamp":1744986476000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Recurrent Intradialytic Hypotension, Associated Risk Factors, and Outcomes in Northern Tanzania: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6910-9615","authenticated-orcid":false,"given":"Fuad H.","family":"Said","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venance P.","family":"Maro","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 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Christian Medical University College Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah K.","family":"Gharib","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia S.","family":"Muhali","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Jonas","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elichilia R.","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"},{"name":"Department of Internal Medicine Kilimanjaro Christian Medical Centre Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elifuraha W.","family":"Mkwizu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"},{"name":"Department of Internal Medicine Kilimanjaro Christian Medical Centre Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Furaha S.","family":"Lyamuya","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania"},{"name":"Department of Internal Medicine Kilimanjaro Christian Medical Centre Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huda F.","family":"Akrabi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi 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Moshi Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002343"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.368"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30045-3"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31694-5"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.983"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282269"},{"issue":"8","key":"e_1_2_12_8_1","article-title":"Outcomes of Dialysis Among Patients With End\u2010Stage Renal Disease (ESRD)","volume":"13","author":"Ejaz 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