{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T17:09:45Z","timestamp":1776964185797,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T00:00:00Z","timestamp":1744934400000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Severe pneumonia is a leading cause of mortality among older adults, particularly in low\u2010income countries like Ethiopia. Despite treatment advancements, the role of different factors in predicting poor outcomes remains understudied. This study aims to assess early indicators poor outcomes in severe pneumonia among older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicenter retrospective cohort study was conducted involving 422 older adults aged over 65 years. Kaplan\u2013Meier survival curves and log\u2010rank tests were utilized to compare survival across categories. Cox regression analysis was performed to evaluate the association between these factors and poor outcomes, while adjusting for potential confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the patients, 13.27% (95% CI: 10.18, 16.88) died from severe pneumonia. CHF (AHR\u2009=\u20092.35, 95% CI: 1.23, 4.49), DM (AHR\u2009=\u20092.52, 95% CI: 1.23, 5.14), and COPD (AHR\u2009=\u20092.59, 95% CI: 1.39, 4.81), elevated creatinine (AHR\u2009=\u20091.63, 95% CI: 1.63, 2.69), and low platelet count (AHR\u2009=\u20092.43, 95% CI: 1.78, 5.34) were significantly associated with poor outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Thrombocytopenia and high creatinine levels may serve as early indicators of poor outcomes in severe pneumonia among older adults. Monitoring these markers is critical for guiding interventions and improving patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.70666","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T17:32:51Z","timestamp":1744997571000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Predictors of Poor Pneumonia Outcomes in Older Adults: A Multicentered Follow\u2010Up Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7199-1249","authenticated-orcid":false,"given":"Tegene Atamenta","family":"Kitaw","sequence":"first","affiliation":[{"name":"Department of Nursing, College of Health Science Woldia University Woldia Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Addisu","family":"Getie","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Medicine and Health Sciences Debre Markos University Debre Markos Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melesse Abiye","family":"Munie","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Health Science Woldia University Woldia Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yabibal Asfaw","family":"Derso","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Health Science Woldia University Woldia Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solomon Gebremichael","family":"Asgedom","sequence":"additional","affiliation":[{"name":"Department of Surgical Nursing School of Nursing, College of Health Sciences and Comprehensive Specialized Hospital, Aksum University Axum Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ribka Nigatu","family":"Haile","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Health Science Woldia University Woldia Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjaed\/mkv052"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-019-0944-1"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191721"},{"key":"e_1_2_12_5_1","unstructured":"S. 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