{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:19:44Z","timestamp":1763727584413,"version":"3.45.0"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hemorrhagic stroke (HS) accounts for ~10% of all first\u2010time strokes, with an increasing incidence in Asia and a scarcity of information available about sex\u2010related differences. This study investigates the independent predictors of HS among Bangladeshi women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Multidimensional Approach of Genotype and Phenotype in Stroke Etiology (MAGPIE) study is a Bangladeshi observational study that recruited nationwide HS patients between 2022 and 2024. We utilized univariate analysis to identify risk patterns in the data sets, whereas a multivariate logistic regression (LR) analysis identified the independent predictors of HS in women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We evaluated a total of 1080 hemorrhagic patients with female predominance (59.5%) and similar age of onset to males (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.38). Although males had significantly higher rates of hypertension (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), diabetes (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008), chronic constipation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), and systolic blood pressure (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), females were found to have significantly higher body mass index (23.1\u2009\u00b1\u20093.1 vs. 21.4\u2009\u00b1\u20092.9;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and paternal diabetes (9.6% vs. 4.8%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) compared to male. Further, the age\u2010adjusted multivariate LR model found paternal diabetes (OR 2.1, 95% CI 1.2\u20133.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) as a potential independent predictor of HS in females compared to males. The area under the receiver operating characteristic (AUROC) curve of 0.67 (95% CI 0.63\u20130.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) with 67.7% sensitivity and 58.2% specificity presents the goodness of fit of the model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Bangladeshi women with a history of paternal diabetes have a 2.1\u2010fold heightened risk of HS than men.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70809","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:32:44Z","timestamp":1745973164000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of Paternal Diabetes With Hemorrhagic Stroke in Bangladeshi Women: The MAGPIE Study"],"prefix":"10.1002","volume":"8","author":[{"given":"Md. Abdullah","family":"Yusuf","sequence":"first","affiliation":[{"name":"Department of Microbiology National Institute of Neurosciences and Hospital Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1927-5023","authenticated-orcid":false,"given":"Redoy","family":"Ranjan","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Royal Holloway University of London London UK"},{"name":"Department of Cardiac Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipannita","family":"Adhikary","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Royal Holloway University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adneen","family":"Moureen","sequence":"additional","affiliation":[{"name":"Tuberculosis New Technologies and Diagnostics, USAID's Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maliha","family":"Hakim","sequence":"additional","affiliation":[{"name":"Department of Neurology National Institute of Neurosciences and Hospital Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"issue":"10","key":"e_1_2_11_2_1","article-title":"A Systematic Review of Major Cardiovascular Risk Factors: A Growing Global Health Concern","volume":"14","author":"Adhikary D.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S502451"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2024.108017"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd12020058"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S166111"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003171"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.576967"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000119386.22691.1C"},{"issue":"3","key":"e_1_2_11_10_1","first-page":"520","article-title":"Stroke in Bangladeshi Patients and Risk Factor","volume":"23","author":"Mohammad Q. 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