{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:18:44Z","timestamp":1763727524925,"version":"3.45.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Stroke survivors with a history of substance abuse often face challenges in their quality of life. This study aimed to evaluate the influence of a spiritual support program on the quality of life of this patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A randomized controlled trial was conducted in the ICU ward of Imam Khomeini Hospital in Iran with stroke survivors who had experienced substance overdose. Participants were randomly assigned to an intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950) receiving a four\u2010session spiritual support program or a control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950). Quality of life was assessed using the Stroke\u2010Specific Quality of Life (SS\u2010QoL) scale at baseline and post\u2010intervention, with data analyzed using SPSS version 25, including\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      , Fisher's exact test, independent\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests, and paired sample\n                      <jats:italic>t<\/jats:italic>\n                      \u2010tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age of participants was 37.89\u2009\u00b1\u200911.32 years in the control group and 38.66\u2009\u00b1\u200911.75 years in the intervention group. The cohort was predominantly male, with 52% of the control group and 54% of the intervention group being men. Most participants were married and employed, with a high prevalence of tobacco use. Before the intervention, there was no significant difference in the mean quality of life score between the groups (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u2009\u22120.123,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.285). Post\u2010intervention, a significant disparity was observed in the mean quality of life score between the groups (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u20091.995,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The intervention group showed a significant improvement in the mean quality of life score (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u20095.155,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and its dimensions post\u2010intervention, while the control group did not show significant changes in quality\u2010of\u2010life scores (\n                      <jats:italic>t<\/jats:italic>\n                      \u2009=\u20091.104,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.609).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The spiritual support program can improve the quality of life for stroke survivors with substance abuse histories, emphasizing the need for holistic, patient\u2010centered care that addresses spiritual needs to enhance well\u2010being and recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>The protocol has been registered at the Thai Clinical Trials Registry (TCTR20250204005).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70814","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T10:39:55Z","timestamp":1746441595000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Spiritual Support Program on Quality\u2010of\u2010Life of Stroke Survivors Post Substance Overdose: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4952-9461","authenticated-orcid":false,"given":"Leyla","family":"Alilu","sequence":"first","affiliation":[{"name":"Department of Medical\u2010Surgical Nursing, School of Nursing and Midwifery Urmia University of Medical Sciences Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansour","family":"Arad","sequence":"additional","affiliation":[{"name":"Nursing and Midwifery Faculty Hamadan University of Medical Sciences Hamadan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7843-0084","authenticated-orcid":false,"given":"Rasoul","family":"Goli","sequence":"additional","affiliation":[{"name":"Department of Medical\u2010Surgical Nursing, School of Nursing and Midwifery Urmia University of Medical Sciences Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amireh","family":"Hassanpour","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Nursing and Midwifery Urmia University of Medical Sciences Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Faraji","sequence":"additional","affiliation":[{"name":"Department of Medical\u2010Surgical Nursing, School of Nursing and Midwifery Urmia University of Medical Sciences Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sorena","family":"Nazarbaghi","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine Urmia University of Medical Sciences Urmia Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016671"},{"key":"e_1_2_12_3_1","unstructured":"World Health Organization \u201cGlobal Health Estimates 2019: Deaths by Cause Age Sex by Country and by Region 2000\u20132019 \u201d (WHO 2020)."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-78248-8"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pbr.2021.06.014"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8091295"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2023.10.002"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/00912174231179320"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2020.12.079"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.25259\/SNI_561_2022"},{"key":"e_1_2_12_11_1","first-page":"161","article-title":"Drug Intoxication","volume":"61","author":"Smith S. 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