{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:22:12Z","timestamp":1763727732903,"version":"3.45.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>During the COVID\u201019 pandemic, the emergence of mucormycosis, a rare but often fatal fungal infection, gained significant attention due to its increased prevalence among immunocompromised patients. This study aimed to determine the prevalence and characterize the clinical features of COVID\u201019\u2010associated mucormycosis in patients admitted to Imam Khomeini Hospital, Ahvaz, Iran.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, cross\u2010sectional study analyzed clinical data from patients admitted between November 2020 and November 2021. Inclusion criteria encompassed individuals with concurrent diagnoses of COVID\u201019 and mucormycosis. Data collected included demographic details, clinical features, comorbidities, laboratory findings, and treatment information. Descriptive statistics were used to summarize patient characteristics, and prevalence estimates were provided with 95% confidence intervals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 12,978 hospitalized patients during the study period, 31 individuals (0.2%, 95% CI: 0.2%\u20130.3%) were diagnosed with COVID\u201019\u2010associated mucormycosis. The prevalence was highest among male patients (54.8%) and those aged 60 years or older (48.4%). Diabetes was the most prevalent comorbidity, and the most frequent clinical symptoms included respiratory distress and cough. Patients with severe COVID\u201019 exhibited a significantly higher prevalence of co\u2010infection, suggesting a greater vulnerability in this subgroup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>COVID\u201019\u2010associated mucormycosis primarily affects elderly male patients with underlying diabetes and severe COVID\u201019 illness. These findings underscore the importance of early detection and intervention, particularly for high\u2010risk individuals. Further research is warranted to optimize prevention and management strategies for this serious complication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70831","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T07:03:57Z","timestamp":1747638237000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Co\u2010Infection of Mucormycosis and COVID\u201019: A Retrospective Cross\u2010Sectional Study of Patients Admitted to Imam Khomeini Hospital in Ahvaz, Iran"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2692-7771","authenticated-orcid":false,"given":"Javad","family":"Zarei","sequence":"first","affiliation":[{"name":"Department of Health Information Technology, School of Allied Medical Sciences Ahvaz\u200e Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6533-6299","authenticated-orcid":false,"given":"Hanieh","family":"Raji","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Air Pollution and Respiratory Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4328-4747","authenticated-orcid":false,"given":"Seyed Mohammad","family":"Alavi","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0801-0126","authenticated-orcid":false,"given":"Farid","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Health Research Institute, Infectious and Tropical Diseases Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9821-5349","authenticated-orcid":false,"given":"Nasrin","family":"Amirrajab","sequence":"additional","affiliation":[{"name":"Department of Laboratory Sciences, School of Allied Medical Sciences Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"},{"name":"Nutrition and Metabolic Disease Research Center, Clinical Sciences Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization \u201cWHO Coronavirus (COVID\u201019) Dashboard \u201d published 2023 https:\/\/covid19.who.int\/."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2648"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2021.05.019"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.11.021"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof7040298"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2709.210934"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof5010026"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12281-019-0337-1"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx101"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.07.011"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1295717"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/588660"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1751"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz1008"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13353"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2023.101393"},{"issue":"3","key":"e_1_2_11_19_1","first-page":"33","article-title":"Prevalence, Predictors, and Outcome of Pulmonary Mucormycosis in COVID\u201019 Associated Rhino Orbital Mucormycosis in a Tertiary Care Center in South India","volume":"9","author":"Sethuraman K. 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