{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:23:22Z","timestamp":1763727802651,"version":"3.45.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>This study aimed to investigate the epidemiological, clinical, and therapeutic aspects of osteoarticular complications in patients with sickle cell disease in Bukavu.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicenter cross\u2010sectional study over 5 years, focusing on 31 patients with sickle cell disease who were admitted for osteoarticular complications in Bukavu. Data were collected from medical records and analyzed with the Statistical Package for Social Science 26 (IBM, SPSS 26).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We recorded 31 (6.07%) sickle cell patients with osteoarticular complications, with a mean age of 10.5\u2009\u00b1\u20095.6 years (extremes: 2\u201330 years). Pain, fever, and functional impotence were the most frequent reasons for consultation with 9 (29.03%) patients. Septic arthritis was the most common complication in 10 (32.26%), followed by osteonecrosis of the femoral head in 8 (25.81%), chronic osteomyelitis in 7 (22.58%) cases, and acute osteomyelitis in 4 (12.70%) patients. The femur was the most affected bone. Articular complications predominantly impacted larger joints, with the knee joint experiencing the highest rate of damage, occurring in 38.71% of cases. Treatment, including medical and surgical methods, was provided in 16 cases (51.6%). Complete healing without residual effects was achieved in 22 patients (70.96%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The osteoarticular complications of sickle cell disease are frequent in the city of Bukavu, and regular monitoring and early consultation would enable early diagnosis and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70861","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T06:40:28Z","timestamp":1748241628000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Osteoarticular Complications of Sickle Cell Disease in Bukavu: A Retrospective Multicenter Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"8","author":[{"given":"Rodrigue Mwenibamba","family":"Mupenda","sequence":"first","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Nechi","family":"Nakashenyi","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5170-7442","authenticated-orcid":false,"given":"Daniel Safari","family":"Nteranya","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviane Feza Bianga","family":"Viviane","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernand Manga","family":"Opondjo","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah Mbula","family":"Mulasi","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier Mbilizi","family":"Kasilembo","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3861-6401","authenticated-orcid":false,"given":"Christian Bisimwa","family":"Wabene","sequence":"additional","affiliation":[{"name":"Cliniques Universitaires de Bukavu, Faculty of Medicine Universit\u00e9 Officielle de Bukavu Bukavu Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene Munyantwari","family":"Akomu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Goma Goma Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwonda","family":"Akinja","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Mbuji Mayi Mbuji Mayi Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Marrie Vianney Tshimbila","family":"Kabangu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Kisangani Kisangani Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_11_2_1","DOI":"10.1001\/jama.2022.10233"},{"doi-asserted-by":"publisher","key":"e_1_2_11_3_1","DOI":"10.7861\/clinmed.2022-0143"},{"doi-asserted-by":"publisher","key":"e_1_2_11_4_1","DOI":"10.1016\/S2352-3026(23)00118-7"},{"doi-asserted-by":"publisher","key":"e_1_2_11_5_1","DOI":"10.2147\/JBM.S406196"},{"doi-asserted-by":"publisher","key":"e_1_2_11_6_1","DOI":"10.1016\/j.admp.2015.04.003"},{"doi-asserted-by":"publisher","key":"e_1_2_11_7_1","DOI":"10.1016\/S2352-3026(22)00004-7"},{"issue":"4","key":"e_1_2_11_8_1","article-title":"Complications Ost\u00e9oarticulaires De La Dr\u00e9panocytose Au D\u00e9partement De P\u00e9diatrie Du CHU Gabriel 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