{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T12:06:00Z","timestamp":1781093160534,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Lumbar disc prolapse (LDP) is a more severe health issue worldwide. Shacklock's neural mobilization is a useful technique for treating prolapsed discs. The study aimed to examine the effectiveness of Shacklock's neural mobilization for acute and subacute LDP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study was a double\u2010blinded, randomized controlled trial. A total of 42 individuals with LDP were allocated randomly by computer\u2010generated numbers to an experimental and a control group. The experimental group got neural mobilization along with usual physiotherapy treatment. The control group got just usual physiotherapy. Postural education was given for both groups in sitting and standing positions. The total number of therapy sessions was eight, with a frequency of four sessions per week for a duration of 2 weeks. The Dallas pain questionnaire (DPQ) and Oswestry disability index (ODI) questionnaire were measured on the initial day and after eight sessions of treatment. The data was analyzed through paired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, unrelated\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, chi\u2010square, and Mann\u2010Whitney U test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A significant improvement of pain in different positions and disability was demonstrated in the within\u2010group analysis by paired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, whereas no significant improvement was found in the between\u2010group analysis by independent sample\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test. The significant change was found on the DPQ score except for two variables. There was no statistically significant association between disability status and gender (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.69) and between disability status and BMI (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.41). A significant difference (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000) was found in both scales.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Shacklock's neural mobilization, along with standard physiotherapy techniques, had a significant impact on pain and disability for people with acute and subacute LDP.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      Zahid Bin Sultan Nahid: CTRI\/2023\/04\/051283\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.70872","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T01:19:51Z","timestamp":1748308791000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effectiveness of Shacklock's Neural Mobilization for Acute and Sub\u2010Acute Lumbar Disc Prolapsed: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0318-475X","authenticated-orcid":false,"given":"Zahid Bin Sultan","family":"Nahid","sequence":"first","affiliation":[{"name":"Department of Physiotherapy SAIC College of Medical Science and Technology Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0239-0113","authenticated-orcid":false,"given":"Faruq","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Centre for the Rehabilitation of the Paralysed (CRP) Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0550-1730","authenticated-orcid":false,"given":"Md Faruqul","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Dhaka College of Physiotherapy Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2268-2109","authenticated-orcid":false,"given":"Zakia","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy SAIC College of Medical Science and Technology Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7457-8683","authenticated-orcid":false,"given":"Md Furatul","family":"Haque","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy SAIC College of Medical Science and Technology Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2067-469X","authenticated-orcid":false,"given":"Asma","family":"Arju","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy SAIC College of Medical Science and Technology Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2645-4249","authenticated-orcid":false,"given":"Md Rafiqul","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy State College of Health Sciences Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4480-6086","authenticated-orcid":false,"given":"Golam","family":"Moula","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Dhaka College of Physiotherapy Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2984-1439","authenticated-orcid":false,"given":"Bibekanonda","family":"Sarker","sequence":"additional","affiliation":[{"name":"Directorate General of Health Sciences (DGHS) Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"5","article-title":"Effect of Neurodynamic Mobilization on Pain and Function in Subjects With Lumbo\u2010Sacral Radiculopathy","volume":"7","author":"Sharma S. S.","year":"2018","journal-title":"Medical Science"},{"issue":"10","key":"e_1_2_12_3_1","article-title":"A Review of Lumbar Radiculopathy, Diagnosis, and Treatment","volume":"11","author":"Berry J. A.","year":"2019","journal-title":"Cureus"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39223.428495.BE"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2007.01.008"},{"issue":"2","key":"e_1_2_12_6_1","first-page":"49","article-title":"A Systematic Review and Meta\u2010Analysis on the Efficacy of Physiotherapy Intervention in Management of Lumbar Prolapsed Intervertebral Disc","volume":"15","author":"Singh V.","year":"2021","journal-title":"International Journal of Health Sciences"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e318183a4a2"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2007.01.004"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2002.13.2.3"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2006.08.004"},{"issue":"4","key":"e_1_2_12_11_1","first-page":"145","article-title":"Incidence of Low Back Pain in Workage Adults in Rural North India","volume":"57","author":"Sharma S. C.","year":"2003","journal-title":"Indian Journal of Medical Sciences"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000088"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.906461"},{"issue":"1","key":"e_1_2_12_14_1","first-page":"37","article-title":"Efficacy of Sciatic Nerve Mobilization in Lumbar Radiculopathy Due to Prolapsed Intervertebral Disc","volume":"10","author":"Yamin F.","year":"2016","journal-title":"Indian Journal of Physiotherapy and Occupational Therapy\u2014An International Journal"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2014.08.006"},{"key":"e_1_2_12_16_1","volume-title":"Clinical Neurodynamics: A New System of Neuromusculoskeletal Treatment","year":"2005"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2017.7117"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200109010-00011"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3329\/bsmmuj.v9i3.29459"},{"issue":"2","key":"e_1_2_12_20_1","first-page":"17","article-title":"Associated Factors of Low Back Pain Among the Workers of Commercial Bank of Ethiopia: Mekelle, North Ethiopia","volume":"3","author":"Singh K.","year":"2019","journal-title":"Research & Reviews: A Journal of Medical Science and Technology"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.21088\/ijfmp.0974.3383.11418.6"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2009.2913"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-35552009005000062"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001295"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/10669817.2022.2065599"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.27.1983"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.21088\/ijfmp.0974.3383.11418.6"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.14474\/ptrs.2023.12.2.92"},{"issue":"1","key":"e_1_2_12_29_1","first-page":"11","article-title":"Effect of Spinal Mobilization With Leg Movement as an Adjunct to Neural Mobilization and Conventional Therapy in Patients With Lumbar Radiculopathy: Randomized Controlled Trial","volume":"6","author":"Das S.","year":"2018","journal-title":"Journal of Medical and Scientific Research"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.70872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:06:27Z","timestamp":1763726787000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.70872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/hsr2.70872"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.70872","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2024-08-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70872"}}