{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T17:03:06Z","timestamp":1784134986698,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>HIV\u2013hepatitis B co\u2010infection rapidly progresses to fibrosis, cirrhosis, and HCC and has a poor prognosis. The study therefore assesses the prevalence of HIV and HIV\u2013hepatitis B co\u2010infection in the Gambia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From June 2012 to September 2019, patients with confirmed diagnosis of HCC were enrolled. All patients medical history, ultrasound scan, fibroscan and laboratory details were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study recruited 476 HCC patients. The prevalence of HIV amongst the HCC patient was 21 (4.4%), and this was higher in males, 19 (4.9%), than in females, 2 (2.2%). The HCC patients with Hepatitis B only were 319 (67.2%). Those HCC patients with HIV\u2010hepatitis B co\u2010infection were 17 (3.6%). HCC patients with HIV\u2013hepatitis B co\u2010infection were much younger and more likely to be male as compared to HCC patients with Hepatitis B only or HCC patients with negative HIV\u2013hepatitis B. There was no difference between the median survivals of the three HCC patient groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The prevalence of HIV in HCC patients is higher than in the general population. HIV\u2013hepatitis B disproportionately affects young men, but there was no difference in survival. This study therefore confirms the need to have an integrated HIV\u2013hepatitis B services in Hepatology clinics or screening programs in the Gambia to early detect co\u2010infections, especially in young men and start them on treatment to prevent chronic liver disease complications and improve prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71006","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T11:59:32Z","timestamp":1752062372000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of HIV and HIV\u2013Hepatitis B Co\u2010Infection in Hepatocellular Carcinoma Patients in the Gambia, 2012\u20132019: A Prospective Cohort Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8162-7363","authenticated-orcid":false,"given":"Sheikh Omar","family":"Bittaye","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia"},{"name":"School of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abubacarr","family":"Kambi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momodou A. I.","family":"Tekanyi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saydiba","family":"Tamba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamin","family":"Bojang","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamin","family":"Sanneh","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momodou Musa","family":"Sisawo","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulie","family":"Jatta","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gibril","family":"Fatty","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Jeng","sequence":"additional","affiliation":[{"name":"Disease Control and Elimination MRC Unit The Gambia @ London School of Hygiene and Tropical Medicine Fajara The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momodou Salieu","family":"Jallow","sequence":"additional","affiliation":[{"name":"School of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia"},{"name":"Pathology Department Edward Francis Small Teaching Hospital Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousman","family":"Leigh","sequence":"additional","affiliation":[{"name":"School of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia"},{"name":"Pathology Department Edward Francis Small Teaching Hospital Banjul The Gambia"},{"name":"American International University Serekunda The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramou","family":"Njie","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Edward Francis Small Teaching Hospital Banjul The Gambia"},{"name":"School of Medicine and Allied Health Sciences University of The Gambia Banjul The Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.08.021"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282539"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.20.00425"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2010.07.004"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.12.338"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.20517\/2394-5079.2022.32"},{"issue":"6","key":"e_1_2_12_9_1","first-page":"10","article-title":"Prevalence of Hepatocellular Carcinoma in HIV Patients Co\u2010Infected or Triple Infected With Hepatitis B and Hepatitis C in a Community Hospital in South Bronx","volume":"14","author":"Mehershanhi S.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075775"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-023-02952-8"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(16)30130-9"},{"key":"e_1_2_12_13_1","unstructured":"\u201cGlobal AIDS Monitoring. 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