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The needs assessment of stakeholders to extract the requirements is pivotal for developing a successful app. This study aims to determine the requirement of a mHealth app for preventing and managing perinatal depression and anxiety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This mixed\u2010methods study was conducted based on four stages. Firstly, requirements were identified through a literature review. Secondly, the draft requirements were presented to an expert panel for review and confirmation. Fifteen experts participated in validating the requirements through the Content Validity Ratio (CVR) and Content Validity Index (CVI). Finally, the Delphi technique was performed to determine the final functional requirements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The literature review retrieved 34 relevant articles and three guidelines. A total of 163 requirements were extracted through a literature search. The expert panel revision resulted in 87 requirements in 13 categories. Seven requirements were removed following CVI and CVR calculation. After the Delphi technique, five requirements were removed. The final list included 75 requirements categorized into 13 groups, including socio\u2010demographic information, pregnancy and delivery, medical history, medication, screening, self\u2010empowerment, warning\/reminder, monitoring, consultation, forum, reports, interface\/framing, and security and confidentiality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These requirements have the potential to help app developers design and assess their apps, and for patients to assess the apps targeting the prevention and management of perinatal depression and anxiety. Further research is required to address the generalizability of this requirement set.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hsr2.71160","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T05:27:51Z","timestamp":1754890071000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Exploring the Requirements for an mHealth App to Prevent and Manage Perinatal Anxiety and Depression"],"prefix":"10.1002","volume":"8","author":[{"given":"Mohammad","family":"Shirdeli","sequence":"first","affiliation":[{"name":"Department of Health Information Management, School of Health Management and Information, Student Research Committee, Health Human Resources Research Center Shiraz University of Medical Science Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Rezaee","sequence":"additional","affiliation":[{"name":"Clinical Education Research Center, Health Human Resources Research Center, School of Health Management and Information Sciences Shiraz University of Medical Science Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9446-8453","authenticated-orcid":false,"given":"Azadeh","family":"Bashiri","sequence":"additional","affiliation":[{"name":"Department of Health Information Management, School of Health Management and Information, Health Human Resources Research Center, Clinical Education Research Center Shiraz University of Medical Science Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash","family":"Mani","sequence":"additional","affiliation":[{"name":"Research Center for Psychiatry and Behavior Science, Hafez Hospital Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1399-9234","authenticated-orcid":false,"given":"Somayyeh","family":"Zakerabasali","sequence":"additional","affiliation":[{"name":"Department of Health Information Management, School of Health Management and Information, Health Human Resources Research Center, Clinical Education Research Center Shiraz University of Medical Science Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Holl","sequence":"additional","affiliation":[{"name":"DigiHealth Institute Neu\u2010Ulm University of Applied Sciences Neu\u2010Ulm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0145-2134(87)90082-2"},{"key":"e_1_2_10_3_1","unstructured":"W. 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