{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T17:29:37Z","timestamp":1787246977679,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:00:00Z","timestamp":1761609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T00:00:00Z","timestamp":1761609600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Viral respiratory tract infections are common in all age groups, and they are responsible for a vast number of health care visits every year. Furthermore, the incidence of respiratory infections is the highest in children. We aimed to determine how infants presenting with fever and symptoms of respiratory infections were treated at Tampere University Hospital (Tays) and their responses to treatment. The secondary purpose was to describe the specific diagnosis behind the respiratory symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was conducted in the Department of Paediatrics in Tays, Finland. Inclusion criteria were age &lt;\u20091 year, fever, and symptoms of a respiratory infection. We documented from the electronic patient records the medication and other treatments the infants received during their hospital stays. For infants given the same medication multiple times, only the first dosing and response to that medication were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 119 episodes (117 infants), 50 (42%) of whom were hospitalized. Symptom\u2010relieving medications, such as paracetamol, were used frequently, with generally good responses. Overall, 59% of the infants were administered antibiotics, the most common indication being otitis media. The most common primary or secondary diagnosis was bronchiolitis or bronchitis (43%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nearly half of the infants needed hospitalization. Symptom\u2010relieving medications, such as analgesics, were a key treatment choice, and the responses were generally good. Although the majority of the infants had a viral infection, antibiotics were used frequently, at least partially due to secondary bacterial infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71414","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:10:39Z","timestamp":1761657039000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of Infants Treated for Respiratory Viral Infections: A Finnish Retrospective Register\u2010Based Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3782-1368","authenticated-orcid":false,"given":"Sallamaria","family":"L\u00e4nsisalo","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health Technology Tampere University Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5989-8615","authenticated-orcid":false,"given":"Paula","family":"Heikkil\u00e4","sequence":"additional","affiliation":[{"name":"Tampere Centre for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University and University Hospital Tampere Finland"},{"name":"Department of Pulmonology, Dermatology and Allergology Tampere University Hospital, Wellbeing Services County of Pirkanmaa Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3270-7660","authenticated-orcid":false,"given":"Sauli","family":"Palmu","sequence":"additional","affiliation":[{"name":"Tampere Centre for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology Tampere University and University Hospital Tampere Finland"},{"name":"Department of Pediatrics Tampere University Hospital, Wellbeing Services County of Pirkanmaa Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(01)01058-0"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12162-9"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13162"},{"issue":"2","key":"e_1_2_13_5_1","first-page":"94","article-title":"Respiratory Syncytial Virus Bronchiolitis in Children","volume":"95","author":"Smith D. K.","year":"2017","journal-title":"American Family Physician"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.08.010"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16061"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7140a1"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-020-02186-7"},{"key":"e_1_2_13_10_1","author":"Members of NICE Guideline Committee","year":"2021","journal-title":"Fever in Under 5S: Assessment and Initial Management"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/children4090081"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245815"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199493"},{"issue":"9","key":"e_1_2_13_14_1","first-page":"817","article-title":"Antibiotic Use in Acute Upper Respiratory Tract Infections","volume":"86","author":"Zoorob R.","year":"2012","journal-title":"American Family Physician"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16323"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2016.11.003"},{"key":"e_1_2_13_17_1","unstructured":"Current Care Guidelines Acute Otitis Media. Working Group Appointed by the Finnish Medical Society Duodecim the Finnish Association of Otolaryngology and Head and Neck Surgery the Finnish Paediatric Society the Finnish Otolaryngological Society and the Finnish Association for General Practice(Finnish Medical Society Duodecim 2017) https:\/\/www.kaypahoito.fi\/en\/ccs00071."},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2742"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000018657"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01016-9"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.70144"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.14713"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-04940-2"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.3205\/id000071"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2491-9"},{"key":"e_1_2_13_26_1","doi-asserted-by":"crossref","unstructured":"F. Y.Aoki M. D.Macleod andP.Paggiaro IMPACT Study Group et al. \u201cEarly Administration of Oral Oseltamivir Increases the Benefits of Influenza Treatment \u201dJournal of Antimicrobial Chemotherapy51 no. 1 (2003): 123\u2013129 https:\/\/doi.org\/10.1093\/jac\/dkg007.","DOI":"10.1093\/jac\/dkg007"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12862"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.71414","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.71414","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.71414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T17:12:20Z","timestamp":1787245940000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.71414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,28]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/hsr2.71414"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.71414","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,28]]},"assertion":[{"value":"2025-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71414"}}