{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T17:29:33Z","timestamp":1787246973140,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T00:00:00Z","timestamp":1762646400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Parvovirus B19 is a common viral pathogen associated with a variety of clinical manifestations, including significant complications during pregnancy such as fetal anemia, miscarriage, and hydrops fetalis. Determining the seroprevalence of B19\u2010specific antibodies in pregnant women is essential for assessing population immunity and potential risk to the fetus. This study aimed to evaluate the seroprevalence of IgG and IgM antibodies against parvovirus B19 among pregnant women attending Ayatollah Rouhani Hospital in Babol, Iran.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted on 247 pregnant women in 2018. Serum samples were analyzed for parvovirus B19\u2010specific IgG and IgM antibodies using enzyme\u2010linked immunosorbent assay (ELISA). Associations between seropositivity and demographic\/clinical variables were statistically analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Out of the 247 participants, 124 (50%) were seropositive for B19\u2010specific IgG, indicating previous exposure. Additionally, 10 of 90 women (11.1%) tested positive for IgM antibodies, suggesting recent infection. No statistically significant associations were found between seropositivity and variables such as age, gestational age, or history of miscarriage in the multivariate analysis, although parity showed significance in the univariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Approximately half of the studied pregnant women had no detectable immunity to parvovirus B19 and were at risk of primary infection during pregnancy. The presence of IgM antibodies in a subset of women highlights the need for increased awareness, routine screening, and preventive strategies to mitigate the risk of vertical transmission and adverse fetal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71474","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T07:34:53Z","timestamp":1762760093000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seroepidemiological Study of Parvovirus B19 Infection Among Pregnant Women Attending Ayatollah Rohani Hospital in Babol, Iran: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"8","author":[{"given":"Zeinab","family":"Darbandi","sequence":"first","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Mohsenfar","sequence":"additional","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0762-5324","authenticated-orcid":false,"given":"Arefeh Ebrahimian","family":"Shiadeh","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Faculty of Medicine Golestan University of Medical Science Gorgan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzane","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, School of Medicine Babol University of Medical Sciences Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soheil","family":"Ebrahimpour","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research 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