{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:04:25Z","timestamp":1788883465833,"version":"build-2803163510"},"reference-count":55,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system, often leading to cognitive and physical impairments. Medication adherence is crucial for managing MS, yet nonadherence remains a significant issue, influenced by factors such as health literacy (HL) and beliefs about medication. This study aimed to evaluate HL, medication adherence, and the association between them among patients with MS in Jordan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 307 patients with MS from Al\u2010Bashir Hospital in Amman, Jordan, participated in this study. Patients completed questionnaires assessing HL (HLS\u2010Q12), medication beliefs (BMQ\u2010Specific), the Communication and Language Assessment for Multiple Sclerosis (CALMS), and Medication Adherence Report Scale (MARS\u20105). Hierarchical logistic regression was conducted to evaluate associations between HL, medication beliefs, and adherence. The study was reported in accordance with the STROBE guidelines for cross\u2010sectional studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median MARS\u20105 score was 25 (IQR: 21\u201325), indicating high adherence, with 77.5% of participants reporting never skipping doses. Higher HLS\u2010Q12 scores were significantly associated with better adherence. Receiving medications with less frequent dosing (i.e., monthly or annually administered injectables) was associated with higher adherence compared to daily dosing regimens (i.e., oral medications). Medication necessity beliefs scores were positively associated with medication adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HL, dosage regimen and medication beliefs are significantly associated with adherence among patients with MS in Jordan. Tailored interventions to enhance HL, and promote positive beliefs about medication are important for supporting adherence and health outcomes in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71672","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T06:55:00Z","timestamp":1766127300000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Health Literacy, Beliefs About Medication, and Medication Adherence in Patients With Multiple Sclerosis in Jordan: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"8","author":[{"given":"Walid","family":"Al\u2010Qerem","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Faculty of Pharmacy Al\u2010Zaytoonah University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawsan","family":"Khdair","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Faculty of Pharmacy Al\u2010Zaytoonah University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dunia","family":"Basem","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Faculty of Pharmacy Al\u2010Zaytoonah University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anan","family":"Jarab","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Faculty of Pharmacy Jordan University of Science and Technology Irbid Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0745-178X","authenticated-orcid":false,"given":"Judith","family":"Eberhardt","sequence":"additional","affiliation":[{"name":"Department of Psychology, School of Social Sciences, Humanities and Law Teesside University Borough Road Middlesbrough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000560"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMRA1401483\/SUPPL_FILE\/NEJMRA1401483_DISCLOSURES.PDF"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ANA.25463"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ANA.25808"},{"key":"e_1_2_14_6_1","first-page":"165","volume-title":"Pharmacy Practice","author":"Horne R.","year":"2001"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870449908407311"},{"key":"e_1_2_14_8_1","unstructured":"World Health Organization. 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