{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:18:30Z","timestamp":1788344310366,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Nonsteroidal anti\u2010inflammatory drugs (NSAIDs) remain the cornerstone of symptomatic management in osteoarthritis (OA) and axial spondyloarthritis (axial SpA), but safety concerns have reshaped prescribing behaviors. This study aimed to describe current NSAID prescribing practices among Moroccan rheumatologists for both conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional descriptive survey was conducted among rheumatologists from public and private sectors. Data were collected using a 30\u2010item validated questionnaire approved by an expert committee.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty\u2010two rheumatologists participated. More than half (56.1%) reported having no absolute age limit for NSAID use, while 24% avoided NSAIDs in patients aged &gt;\u200975 years. The most concerning combination was NSAIDs with vitamin K antagonists (96.3%), and the most cited contraindication was active gastroduodenal ulcer (85.4%). Only 13.4% routinely requested renal function tests before prescribing NSAIDs. Proton pump inhibitors were co\u2010prescribed mainly for a history of gastrointestinal bleeding (93.9% with conventional NSAIDs; 87.8% with coxibs). Naproxen (95.1%), celecoxib (63.4%), and meloxicam (58.5%) were considered the safest for cardiovascular risk. Celecoxib was the first\u2010line NSAID for OA (47.6%), while diclofenac was preferred for axial SpA (34.9%) and celecoxib in patients with inflammatory bowel disease (73.2%). Nearly half (47.6%) prescribed NSAIDs on an as\u2010needed basis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>NSAID prescribing in OA and axial SpA is increasingly personalized, with choices guided by comorbidities and safety concerns. Celecoxib is preferred for OA, while diclofenac remains first\u2010line for axial SpA, with caution in patients at gastrointestinal or cardiovascular risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71764","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T10:18:14Z","timestamp":1779272294000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Current Trends in NSAID Prescribing for Osteoarthritis and Axial Spondyloarthritis: Insights From Moroccan Rheumatologists Practices"],"prefix":"10.1002","volume":"9","author":[{"given":"Imane","family":"El Binoune","sequence":"first","affiliation":[{"name":"Department of Rheumatology A, El Ayachi Hospital Ibn Sina University Hospital, Mohammed V University Rabat\u2010Sal\u00e9 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3516-7209","authenticated-orcid":false,"given":"Benyahia","family":"Zineb","sequence":"additional","affiliation":[{"name":"Department of Rheumatology A, El Ayachi Hospital Ibn Sina University Hospital, Mohammed V University Rabat\u2010Sal\u00e9 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samira","family":"Rostom","sequence":"additional","affiliation":[{"name":"Department of Rheumatology A, El Ayachi Hospital Ibn Sina University Hospital, Mohammed V University Rabat\u2010Sal\u00e9 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bouchra","family":"Amine","sequence":"additional","affiliation":[{"name":"Department of Rheumatology A, El Ayachi Hospital Ibn Sina University Hospital, Mohammed V University Rabat\u2010Sal\u00e9 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachid","family":"Bahiri","sequence":"additional","affiliation":[{"name":"Department of Rheumatology A, El Ayachi Hospital Ibn Sina University Hospital, Mohammed V University Rabat\u2010Sal\u00e9 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000479"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000475"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319300"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24131"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-223296"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112958"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2020.09.004"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40256-016-0200-5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1611593"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-022-01211-1"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-019-00660-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60900-9"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2019.06.011"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-213826"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1903768"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2018.02.522"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/EBP.0000000000000296"},{"key":"e_1_2_10_19_1","first-page":"254","volume-title":"La cr\u00e9ation romanesque chez Williams Sassine","author":"Atcha P. 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