{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T04:07:14Z","timestamp":1789963634149,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Acute respiratory infections (ARIs) have a relevant impact on public health in terms of prevalence and costs associated with the diseases. While the COVID\u201019 pandemic highlighted the need to adopt accurate surveillance systems to face new emergencies, the aim of our work is to describe ARIs other then COVID\u201019 and their impact on healthcare facilities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study used an ecological approach to connect emergency department records and laboratory test results from a University Hospital in Italy. A time\u2010series analysis has been performed to assess the association between weekly pathogen\u2010specific positivity counts and ARI\u2010related ED admissions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the study period, 33,101 ED presentations for ARI were registered, resulting in 7426 hospital admissions. ARI cases and viral diagnoses showed a seasonal peak during the late weeks of the year and early weeks of the following one. A reduction in ED admissions has been found in 2020, while the average weekly rate was 30.8% in 2020, as compared with 21.7% in 2017\u20132019. Analysis by age group showed a peak of accesses in the last weeks of 2021 for the &lt;\u20091 and 1\u20134 years old.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Data on ARI\u2010related admissions highlight seasonal trends and age\u2010related vulnerabilities, providing evidence to guide public health policies and support health system preparedness to respond to future epidemic waves.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.71870","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:59:03Z","timestamp":1772999943000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Burden of Acute Respiratory Infections on Emergency Departments: A Retrospective Study From a University Hospital in Central Italy"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7720-7013","authenticated-orcid":false,"given":"Nunzio","family":"Zotti","sequence":"first","affiliation":[{"name":"Department of Translational Research and the New Technologies in Medicine and Surgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6699-2426","authenticated-orcid":false,"given":"Francesca","family":"Di Serafino","sequence":"additional","affiliation":[{"name":"Department of Translational Research and the New Technologies in Medicine and Surgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Carmisciano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Pisa Pisa Italy"},{"name":"Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Baglietto","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Cristofano","sequence":"additional","affiliation":[{"name":"Pisa University Hospital Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Foltran","sequence":"additional","affiliation":[{"name":"Pisa University Hospital Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ombretta","family":"Paolilli","sequence":"additional","affiliation":[{"name":"Pisa University Hospital Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Davide","family":"Porretta","sequence":"additional","affiliation":[{"name":"Department of Translational Research and the New Technologies in Medicine and Surgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1258-1650","authenticated-orcid":false,"given":"Guglielmo","family":"Arzilli","sequence":"additional","affiliation":[{"name":"Department of Translational Research and the New Technologies in Medicine and Surgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Pistello","sequence":"additional","affiliation":[{"name":"Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Department of Translational Research and the New Technologies in Medicine and Surgery University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"e_1_2_15_2_1","unstructured":"World Health Organization \u201cTrends of Acute Respiratory Infection Including Human Metapneumovirus in the Northern Hemisphere \u201d accessed October 2 2025 https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2025-DON550."},{"key":"e_1_2_15_3_1","volume-title":"National Strategic and Operational Plan for Influenza Pandemic Preparedness and Response (PanFlu 2021\u20102023)","author":"Italian Ministry of Health","year":"2021"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12592"},{"key":"e_1_2_15_5_1","unstructured":"WHO Global Epidemiological Surveillance Standards for Influenza(WHO 2014)."},{"key":"e_1_2_15_6_1","volume-title":"Infectious Diseases","author":"Armstrong 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Suh X. Jiang N. Movva et al. \u201c1508. Hospitalizations and Emergency Department Visits for Respiratory Syncytial Virus Among Infants Aged <\u20091 Year in the United States: An Analysis of Nationwide Inpatient and Emergency Room Data \u201d supplement Open Forum Infectious Diseases7 no. Supplement_1 (October 2020): S757\u2013S758 https:\/\/doi.org\/10.1093\/ofid\/ofaa439.1689.","DOI":"10.1093\/ofid\/ofaa439.1689"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000092191.78339.1a"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2022.10.001"},{"issue":"6","key":"e_1_2_15_14_1","first-page":"867","article-title":"The Burden of Influenza Hospitalizations in the United States, 2010\u20132016","volume":"67","author":"Chaves S. 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