{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:41:28Z","timestamp":1789576888875,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T00:00:00Z","timestamp":1777766400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>CapsoCam provides a 360\u00b0 panoramic\u2010view in capsule endoscopy (CE). This study aimed to conduct the initial systematic review and meta\u2010analysis on the diagnostic efficacy and clinical aspects of CapsoCam in patients with Suspected small bowel bleeding (SSBB), potentially comparing it to forward\u2010view CE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of PubMed, Embase, and Scopus databases was performed for human studies reporting outcomes of interest up to January 2025. Titles and abstracts were screened, and full\u2010texts were selected based on predefined inclusion criteria by two reviewers. The quality assessment used Joanna Briggs Institute checklist. Meta\u2010analysis used a random\u2010effects model with a 95% confidence interval (CI). Publication bias was evaluated using Egger and Begg's tests. A leave\u2010one\u2010out sensitivity analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five studies met the inclusion criteria. The meta\u2010analysis revealed no statistically significant difference in diagnostic yield between the two CE types in cases of SSBB (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.89, 95% CI: \u22120.08 to 0.09). Egger's test and Begg's test showed no significant publication bias. Comparative analysis between panoramic and forward\u2010view CEs demonstrated similar performance for small bowel transit time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.58, 95% CI: \u22120.33 to 0.59), although evaluation time was significantly longer with CapsoCam (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001, 95% CI: 0.42 to 1.60). The risk difference in completion rates was not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.91, 95% CI: \u22120.13 to 0.15). Subgroup analyses showed no significant differences in diagnostic yield or other outcomes between CapsoCam PLUS and SV\u20101, or by study design.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our analysis suggests that CapsoCam demonstrates comparable performance to forward\u2010view CE in terms of diagnostic reliability, clinical efficacy, and safety profile, except for reading time. However, the limited number of studies underscores the need for further research to validate CapsoCam's usability in routine clinical practice for SSBB patients compared to forward\u2010view CE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72095","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:50:47Z","timestamp":1777870247000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Efficacy and Clinical Aspects of Panoramic\u2010View Versus Forward\u2010View Capsule Endoscopy for Suspected Small Bowel Bleeding: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6655-1501","authenticated-orcid":false,"given":"Ilya","family":"Saadati","sequence":"first","affiliation":[{"name":"Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Centre, Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9612-2587","authenticated-orcid":false,"given":"Reza","family":"Elahi","sequence":"additional","affiliation":[{"name":"Department of Radiology Zanjan University of Medical Sciences Zanjan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0700-1431","authenticated-orcid":false,"given":"Mehdi Azizmohammad","family":"Looha","sequence":"additional","affiliation":[{"name":"Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Centre, Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9295-9283","authenticated-orcid":false,"given":"Seyed Amir Ahmad","family":"Safavi\u2010Naini","sequence":"additional","affiliation":[{"name":"Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Centre, Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3420-5608","authenticated-orcid":false,"given":"Shabnam","family":"Shahrokh","sequence":"additional","affiliation":[{"name":"Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Centre, Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,3]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.70011"},{"issue":"6","key":"e_1_2_15_3_1","first-page":"479","article-title":"Prospective Randomized Comparison Between Axial\u2010 and Lateral\u2010Viewing Capsule Endoscopy Systems in Patients With Obscure Digestive Bleeding","volume":"46","author":"Pioche M.","year":"2014","journal-title":"Endoscopy"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.07.063"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jcag\/gwaa042"},{"issue":"4","key":"e_1_2_15_6_1","first-page":"365","article-title":"Looking Forwards: Not Necessarily the Best in Capsule Endoscopy?","volume":"26","author":"Koulaouzidis A.","year":"2013","journal-title":"Annals of Gastroenterology"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-8-24"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-40244"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000994"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2023.04.1886"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.389"},{"issue":"8","key":"e_1_2_15_13_1","first-page":"454","article-title":"Panoramic Versus Axial Small Bowel Capsule Endoscopy in Overt Obscure Gastrointestinal Bleeding","volume":"7","author":"Chetcuti Zammit S.","year":"2019","journal-title":"United European Gastroenterology Journal"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2017.03.15"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/518718"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-870264"},{"key":"e_1_2_15_17_1","unstructured":"The EndNote Team. 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