{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T18:25:30Z","timestamp":1787250330481,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a cross\u2010sectional research study design. We included a sample of 354 adolescent girls from four preparatory schools. Data was collected in two phases. The first phase used a structured interview questionnaire. The second phase included determining the prevalence of uropathogens among adolescent girls with symptomatic or asymptomatic bacteriuria. Phenotypic identification of isolated species and antimicrobial profiling to determine if there are multiple drug resistance (MDR) patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We observed that 28% of adolescent girls were infected with UTIs. The multiple drug resistance (MDR) uropathogens among isolated Gram\u2010negative species were 31.8%. About 20.5% of\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      , 40% of\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      , 30% of\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      , 50% of\n                      <jats:italic>Proteus mirabilis<\/jats:italic>\n                      , 100% of\n                      <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                      , and 14.2% of\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      were multiple drug resistance (MDR). Extended\u2010Spectrum Beta\u2010Lactamase (ESBL) production among Gram\u2010negative isolates was 18.1%, and they were 10.2% in\n                      <jats:italic>E. coli<\/jats:italic>\n                      , 20% in\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      , 20% in\n                      <jats:italic>P. aeruginosa<\/jats:italic>\n                      , 50% in\n                      <jats:italic>P. mirabilis<\/jats:italic>\n                      , and 100% in\n                      <jats:italic>A. baumannii<\/jats:italic>\n                      . Among the Gram\u2010positive isolates (29%),\n                      <jats:italic>S. aureus<\/jats:italic>\n                      isolates were Methicillin\u2010Resistant\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      (MRSA). There were significant effects with mother education, father occupation, and social class with\n                      <jats:italic>p<\/jats:italic>\n                      \u2010values of &lt;\u20090.001, 0.006, and 0.03.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>UTIs are a major health issue among adolescent girls, with a 28% prevalence. The drug resistance rate of Gram\u2010negative isolates was high for ampicillin, as well as Gram\u2010positive isolates; especially MRSA showed high resistance to penicillin. So, we recommend future continuous screening measures for UTIs among adolescent girls in community settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72104","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:39:48Z","timestamp":1773387588000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bacterial Profiling and Antibiotic Resistance Pattern of Uropathogens Isolated From Adolescent Girls With Bacteriuria: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"given":"Shimaa Abdelrahim","family":"Khalaf","sequence":"first","affiliation":[{"name":"Medical\u2010Surgical Nursing Department, College of Applied Medical Sciences in Yanbu Governorate, Madinah, Saudia Arabia, Health and Life Research Centre, Madinah Taibah University Madinah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7041-444X","authenticated-orcid":false,"given":"Mona Gamal","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Adult Health Nursing Department, RAK College of Nursing RAK Medical and Health Sciences University Ras Al Khaimah UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal A.","family":"Elkhawaga","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunology, Faculty of Medicine Assiut University Assiut Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0962-1407","authenticated-orcid":false,"given":"Iftekhar","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Asia Pacific Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2820-3144","authenticated-orcid":false,"given":"Md. Rabiul","family":"Islam","sequence":"additional","affiliation":[{"name":"School of Pharmacy BRAC University Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaimaa M.","family":"Goda","sequence":"additional","affiliation":[{"name":"Department of Community Health Nursing, Faculty of Nursing Assiut University  Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4246780"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuri.2021.100026"},{"issue":"07","key":"e_1_2_13_4_1","first-page":"5","article-title":"Urinary Tract Infection\u2010Knowledge and Habitual Practices Among Adolescent Girls Residing in College Hostel of Mangaluru, India: A Cross\u2010Sectional Study","volume":"15","author":"Sequera K.","year":"2021","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12301-020-00111-z"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.5455\/ijmsph.2020.09153202023092020"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08578-1"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejhc.2020.132988"},{"issue":"01","key":"e_1_2_13_9_1","first-page":"1146","article-title":"An Interventional Study on Knowledge, Attitude & Practice Towards Urinary Tract Infection Among Adolescent Girls Students in Selected Girls Schools in Chitradurga City","volume":"8","author":"Vijayan A.","year":"2018","journal-title":"Indo American Journal of Pharmaceutical Research"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.52225\/narra.v3i1.104"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S464501"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S217574"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3432"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2017.07.002"},{"key":"e_1_2_13_15_1","volume-title":"Global Priority List of Antibiotic\u2010Resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics","author":"World Health Organization","year":"2017"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287219832172"},{"issue":"1","key":"e_1_2_13_17_1","first-page":"42","article-title":"Family Socio\u2010Economic Status Scale","volume":"28","author":"Abd El\u2010Tawab A.","year":"2012","journal-title":"Journal of Faculty of Education, Assiut University"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.21608\/jhiph.2019.49259"},{"key":"e_1_2_13_19_1","first-page":"33","article-title":"Biochemical Profile\u2010Based Microbial Identification Systems","volume":"1","author":"Hafeez S.","year":"2018","journal-title":"Advanced Techniques in Diagnostic Microbiology: Volume 1: Techniques"},{"key":"e_1_2_13_20_1","volume-title":"Microbiology: A Laboratory Manual","author":"Cappuccino J. 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