{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:19:23Z","timestamp":1783023563353,"version":"3.54.6"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["75D30122C13379"],"award-info":[{"award-number":["75D30122C13379"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Despite evidence of effectiveness, oral antivirals for COVID\u201019 are underused, with significant variation across populations. This study examines COVID\u201019 treatment awareness, knowledge, access, trusted sources, and willingness to use among diverse essential workers in Tennessee during May 18, 2023\u2013June 1, 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Participants enrolled in a prospective community cohort study completed an enrollment survey on demographics, medical history, and vaccination status. Quarterly cross\u2010sectional surveys assessed knowledge, awareness, access, trust, and willingness to use COVID\u201019 antivirals. Knowledge, access, and trust were measured using five\u2010point Likert\u2010type scales, and knowledge was converted into a score based on number of correct responses. Awareness and willingness were assessed using yes\/no\/unsure responses. Responses from survey respondents with risk factors for severe COVID\u201019 were assessed. Descriptive analyses and\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      tests assessed differences across demographic and health characteristics. Multivariable log\u2010binomial regression modeling was used to estimate unadjusted and adjusted prevalence ratios for key outcomes by demographic and health characteristic with 95% confidence intervals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 1289 respondents with risk factors for severe COVID\u201019, over 50% were aware of COVID\u201019 antivirals; 69% were willing to take antivirals if recommended by their healthcare provider. Adjusted models showed older respondents had higher awareness, knowledge, access and trust in doctors. Black non\u2010Hispanic respondents, those with lower education, and those with fewer vaccinations were less likely to be aware of antivirals, answer knowledge questions correctly, or report willingness to use antivirals if recommended. Hispanic respondents reported less awareness, knowledge, and lower trust in doctors as a good source of information about COVID\u201019 antivirals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although willingness to use COVID\u201019 antivirals was relatively high among diverse essential workers with risk factors for severe COVID\u201019, there was variation based on demographic and health factors. This study identifies key gaps, providing a foundation for developing new approaches to improve access to antiviral treatments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72157","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T11:22:42Z","timestamp":1776165762000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["COVID\u201019 Antiviral Treatment: Examining Knowledge, Access, Trust in Sources of Information and Willingness to Use Among Essential Workers: A Cross\u2010Sectional Survey of Cohort Participants"],"prefix":"10.1002","volume":"9","author":[{"given":"Jenae","family":"Sanders","sequence":"first","affiliation":[{"name":"Oak Ridge Institute for Science and Education Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jade","family":"James\u2010Gist","sequence":"additional","affiliation":[{"name":"Centers for Disease 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