{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:48:26Z","timestamp":1787064506364,"version":"build-2736575974"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The burden of viral co\u2010infections among COVID\u201019 patients is underexplored in low\u2010resource settings such as Burkina Faso. This study aimed to determine the prevalence and associated factors of respiratory viral co\u2010infections among laboratory\u2010confirmed COVID\u201019 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted from January 1 to December 31, 2023, across 13 sentinel sites in Burkina Faso. Patients presenting with influenza\u2010like illness or severe acute respiratory infection had nasopharyngeal and\/or oropharyngeal swabs collected and tested for SARS\u2010CoV\u20102 and other respiratory viruses using multiplex real\u2010time RT\u2010PCR. Descriptive statistics, univariate, and multivariate logistic regression analyses were performed to identify predictors of viral co\u2010infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 201 SARS\u2010CoV\u20102\u2010positive patients enrolled (median age: 1 year; interquartile range: 0.5\u20137). Co\u2010infections was identified in 48.8% (95% CI: 41.8\u201355.6) of cases and a single co\u2010infections was detected in 33.8% (95% CI: 27.5\u201340.6) of patients. Human rhinovirus (17.9%), adenovirus (14.4%), respiratory syncytial virus (11.4%), and influenza A\/B (9.9%) were most frequently detected. In multivariate analysis, children aged 6 months to 14 years had higher odds of co\u2010infection (aOR 2.7; 95% CI: 1.2\u20135.9;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013). Fever (aOR 2.6; 95% CI: 1.3\u20135.5;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008) and hospitalization (aOR 4.3; 95% CI: 1.6\u201312.0;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) were also independently associated with co\u2010infection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Viral co\u2010infections were frequent among SARS\u2010CoV\u20102 positive patients, particularly in children and hospitalized individuals. Strengthening multiplex diagnostic capacity and integrated respiratory virus surveillance in resource\u2010limited settings may improve clinical management and inform public health response strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72339","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:31:54Z","timestamp":1776400314000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Respiratory Viral Co\u2010Infections in SARS\u2010CoV\u20102 Positive Patients in Burkina Faso: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7633-7999","authenticated-orcid":false,"given":"Benjamin W. 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