{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T19:15:00Z","timestamp":1787685300583,"version":"build-2784847793"},"reference-count":60,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Alcoholic cardiomyopathy (ACM) poses a significant global health challenge, yet its impact on elderly populations across regions remains underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using Global Burden of Disease (GBD) 2021 data sourced from the official visualization platform, we analyzed ACM burden among individuals aged \u2265\u200960 years across 204 countries (1990\u20132021). Age\u2010standardized rates (ASR) for prevalence, mortality, and disability\u2010adjusted life years (DALYs) were calculated. Trends were assessed via estimated annual percentage change and Joinpoint regression. Future burden (2022\u20132050) was projected using Bayesian age\u2010period\u2010cohort models. Inequalities were measured using Slope and Concentration Indices, while frontier analysis identified optimization potential.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 2021, global age\u2010standardized prevalence, mortality, and DALY rates were 19.33, 2.64, and 58.55 per 100,000, respectively, declining since 1990. Eastern Europe exhibited the highest burden (ASDR: 645.87), notably in Hungary, Russia, and Latvia. Males experienced 3\u20135 times higher rates than females. While Southern Latin America saw substantial declines, the Caribbean observed increases. A positive correlation existed between the Socio\u2010demographic Index (SDI) and ASRs. Decomposition analysis indicated population growth drove prevalence increases, whereas epidemiological improvements reduced mortality. Projections suggest a slight prevalence rise by 2050. Alcohol consumption remained the primary risk factor, especially in high\u2010SDI regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although age\u2010standardized ACM burden decreased among the elderly from 1990 to 2021, absolute numbers rose due to population aging and growth. Targeted interventions are needed, particularly in high\u2010burden regions and among males.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72358","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T04:26:55Z","timestamp":1776227215000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Global Burden of Alcoholic Cardiomyopathy in Adults Aged 60 and Older From 1990 to 2021: A Secondary Analysis of Global Burden of Disease 2021 Data"],"prefix":"10.1002","volume":"9","author":[{"given":"Siyi","family":"Xu","sequence":"first","affiliation":[{"name":"Heart Center, Department of Electrocardiographic &amp; Cardiac Examination, Zhejiang Provincial People's Hospital, Affiliated People's Hospital Hangzhou Medical College Hangzhou Zhejiang 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