{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:18:49Z","timestamp":1783023529002,"version":"3.54.6"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is still a dearth of information on the prevalence and histological patterns of head and neck tumors (HNT) in Ghana, which emphasizes the need for regional studies to learn more about their distribution and clinical features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Thus, the present study aimed to describe the anatomical pattern and clinicopathological features among patients with HNT at some selected hospitals in Ghana.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>The study was retrospective in design, which consisted of laboratory analysis of archived HNT tissues. The study was conducted with 250 archived paraffin\u2010embedded HNT tissue samples from the Pathology Department of Cape Coast Teaching Hospital and Komfo Anokye Teaching Hospital in Ghana. The various tumor grades were analyzed using hematoxylin and eosin staining on tissue samples from a consecutive series of 150 HNT samples, out of 250 patients who underwent tumor resection over a 4\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 148 males and 102 females, giving a male\u2010to\u2010female ratio of 1.45:1. The age range was 10\u201389 years. The commonest anatomical site of patients with the HNT was the oral cavity (34%), followed by the nasal cavity (25.2%) and mandible (24%). The majority of the patients with HNT were recorded in 2018 (23%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study reveals that the oral cavity is the commonest HNT in Ghana, with a higher occurrence observed in patients above 40 years old. Therefore, there is a need to undertake public health education to raise awareness to promote early detection and management of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72395","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T05:36:09Z","timestamp":1777008969000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological Features and Anatomical Patterns of Head and Neck Tumors From Cape Coast Teaching Hospital and Komfo Anokye Teaching Hospital in Ghana: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6668-0729","authenticated-orcid":false,"given":"Roland Osei","family":"Saahene","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, School of Medical Sciences, College of Health and Allied Sciences University of Cape Coast Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9229-5605","authenticated-orcid":false,"given":"Precious","family":"Barnes","sequence":"additional","affiliation":[{"name":"Department of Chemical Pathology, School of Medical Sciences, College of Health and Allied Sciences University of Cape Coast Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. A.","family":"Yeboah","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine, School of Medical Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5207-5942","authenticated-orcid":false,"given":"Du\u2010Bois","family":"Asante","sequence":"additional","affiliation":[{"name":"Department of Forensic Sciences, School of Biological Sciences, College of Agricultural and Natural Sciences University of Cape Coast Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvis","family":"Agbo","sequence":"additional","affiliation":[{"name":"Department of Human Anatomy, Histology and Embryology, College of Medicine Jinggangshan University Ji'an City China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel Kofi","family":"Arhin","sequence":"additional","affiliation":[{"name":"Department of Physiology, School of Medical Sciences, College of Health and Allied Sciences University of Cape Coast Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvester Ackah","family":"Famieh","sequence":"additional","affiliation":[{"name":"Department of Physician Assistant Studies, School of Medical Sciences, College of Health and Allied Sciences University of Cape Coast Cape Coast Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2982"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2014.01.001"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-010-9564-z"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djk179"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0710"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.55.2.74"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20740"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-803678-5.00116-8"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-72992008000100011"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2015.03.001"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02907731"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.4236\/ijohns.2014.35050"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21654"},{"key":"e_1_2_13_15_1","first-page":"85","article-title":"Delays in Diagnosis, Referral and Management of Head and Neck Cancer Presenting at Kenyatta National Hospital, Nairobi","volume":"83","author":"Onyango J.","year":"2006","journal-title":"East African Medical Journal"},{"key":"e_1_2_13_16_1","first-page":"21","article-title":"Pattern of Head and Neck Cancer in Yemen","volume":"7","author":"Abdul\u2010Hamid G.","year":"2010","journal-title":"Gulf Journal of Oncology"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-0347"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijos.2014.48"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/JOM.0000000000001386"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104816"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011610"},{"key":"e_1_2_13_22_1","first-page":"994","article-title":"Specific Association of Epstein\u2010Barr Virus With Lymphoepithelial Carcinoma Among Tumors and Tumorlike Lesions of the Salivary Gland","volume":"118","author":"Chan J. 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