{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T10:19:39Z","timestamp":1788344379203,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Dialysis headache is a common complication of hemodialysis that negatively affects patients' comfort and quality of life. Due to the limitations and potential adverse effects of pharmacological treatments in patients with renal impairment, this study aimed to compare the effectiveness of acupressure and eucalyptus inhalation on headache severity in patients undergoing hemodialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study was a randomized controlled clinical trial conducted on patients undergoing hemodialysis at the Salam Dialysis Center in Tehran in 2023. Participants were selected through convenience sampling and then randomly assigned to three groups: acupressure, eucalyptus inhalation, and control (11 patients in each group). The control group received routine care only. Data were analyzed using appropriate statistical tests in SPSS version 26 at a significance level of 0.05. This randomized controlled clinical trial with a pretest\u2013posttest design was conducted in 2023 at the Salam Dialysis Center in Tehran, Iran. Thirty\u2010three patients were selected through convenience sampling and randomly allocated into three groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911 each): acupressure, eucalyptus inhalation, and control. In the acupressure group, pressure was applied to the HeGu (LI4), Yintang, Taiyang, and GB20 points for 1\u2009min each during the first 20\u2009min of dialysis across three consecutive sessions. In the eucalyptus group, participants inhaled 1\u2009mL of eucalyptus oil from a distance of 30\u2009cm for 5\u2009min at the beginning of dialysis. Headache severity was measured using the Numeric Rating Scale (0\u201310) before and after intervention. Data were analyzed using repeated\u2010measures ANOVA and Bonferroni post hoc tests in SPSS version 26 (two\u2010sided tests,\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The participants consisted of 18 men (54.5%) and 15 women (45.4%), with a mean age of 55.30\u2009\u00b1\u200914.97 years. No significant differences were observed among the three groups regarding demographic and clinical characteristics (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). No significant differences were observed among the groups at baseline (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00). After the intervention, headache severity significantly decreased in both acupressure and eucalyptus groups compared with control (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The time\u2009\u00d7\u2009group interaction effect was significant (\n                      <jats:italic>F<\/jats:italic>\n                      <jats:sub>(2,30)<\/jats:sub>\n                      \u2009=\u200933.76,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, \u03b7\u00b2\u2009=\u20090.692). No significant difference was found between acupressure and eucalyptus groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both eucalyptus inhalation and acupressure demonstrated potential effectiveness in reducing headache severity in patients undergoing hemodialysis. These simple, low\u2010cost, and non\u2010invasive interventions may be considered as complementary approaches in dialysis care to improve patient comfort and reduce headache\u2010related discomfort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72494","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T03:44:47Z","timestamp":1778471087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Effectiveness of Acupressure and Eucalyptus Aromatherapy on Headache Severity in Hemodialysis Patients: A Randomized Controlled Clinical Trial With a Pretest\u2013Posttest Design"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0325-8416","authenticated-orcid":false,"given":"Mohammad Mahdi","family":"Narimani","sequence":"first","affiliation":[{"name":"Community Health Research Center, Isf.C., Islamic Azad University Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6025-4879","authenticated-orcid":false,"given":"Mohadeseh","family":"Motamed\u2010Jahromi","sequence":"additional","affiliation":[{"name":"Department of Public Health School of Health, Fasa University of Medical Sciences Fasa Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0210-7429","authenticated-orcid":false,"given":"Maryam","family":"Radmehr","sequence":"additional","affiliation":[{"name":"Community Health Research Center, Isf.C., Islamic Azad University Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2022.2144373"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000514550"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0284422"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcs8050172"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/aian.aian_404_21"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-023-01701-2"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5281\/zenoda.13888488"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/0004-282x-anp-2021-0133"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1721199"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1173363"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13020-025-01105-1"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-025-10068-w"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcme.2016.06.004"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.explore.2022.03.002"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/acu.2023.0001"},{"issue":"203","key":"e_1_2_12_17_1","first-page":"83","article-title":"Efficacy of Acupressure on Intensity of Acute Migraine in Patients Attending an Emergency Department: A Randomized Clinical Trial","volume":"31","author":"Seydi P.","year":"2021","journal-title":"Journal of Mazandaran University of Medical Sciences"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-023-01237-6"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conctc.2022.100976"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-024-01588-8"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/502727"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.34172\/jcs.2022.20"},{"issue":"1","key":"e_1_2_12_23_1","first-page":"47","article-title":"Psychometric Properties of Pain Intensity Scales in Isfahanian Geriatric Population","volume":"5","author":"Nasiriani K.","year":"2019","journal-title":"Elderly Health Journal"},{"key":"e_1_2_12_24_1","first-page":"1","article-title":"The Effect of Inhalation Aromatherapy Using Lavender Oil on the Severity of Headache in Hemodialysis Patients","volume":"27","author":"Jamshidi Z.","year":"2021","journal-title":"HAYAT"},{"issue":"1","key":"e_1_2_12_25_1","first-page":"12","article-title":"Acupressure as Method for Reducing Head Pain in Tension Type Headache: Case Report","volume":"3","author":"Suaib W. 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