{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:02:52Z","timestamp":1789380172409,"version":"build-2803163510"},"reference-count":65,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>This study aims to explore the nutrient patterns of macronutrients and micronutrients in healthy people and individuals newly diagnosed with rheumatoid arthritis (RA) and their associations with the risk of RA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This case\u2010control study involved 50 RA patients and 100 matched healthy controls. Dietary intakes were obtained using valid food frequency questionnaires (FFQ). Factor analysis was performed to identify nutritional patterns. Multivariable analysis was performed to assess the relationship between each detected nutrient pattern and the risk of RA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Weight, BMI, waist circumference, physical inactivity, and prevalence of individuals with a familial history of RA were significantly higher in RA patients than in individuals without RA (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Four nutrient patterns were identified, accounting for 71.65% of the total variance. The first (high intake of vitamin D, protein, selenium, and cholesterol), third (high intake of vitamin C, calcium, and dietary fiber), and fourth (high intake of iron and vitamin E) identified patterns were inversely associated with the risk of RA, in contrast to the second pattern (high intake of total fat, trans fatty acids, saturated fatty acids (SFA), higher dietary serving score (DSS) and a higher dietary inflammatory index (DII)), which was directly related to the RA risk (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study revealed that dietary patterns that are high in DSS and DII scores, total fat, SFA, and trans fatty acids may be related to the risk of RA. Also, it was shown that dietary contents of protein, cholesterol, fiber, vitamin D, vitamin C, vitamin E, selenium, and calcium could be associated with the RA pathogenesis. To reach a definitive finding regarding the association of each nutrient with the risk of RA, conducting more high\u2010quality cohort studies with a large sample size is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72553","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T06:30:07Z","timestamp":1784183407000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Association of Micro\u2010 and Macro\u2010Nutrient Patterns With the Risk of Rheumatoid Arthritis in Newly Diagnosed Cases: A Case\u2010Control Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2729-9212","authenticated-orcid":false,"given":"Sajedeh","family":"Jandari","sequence":"first","affiliation":[{"name":"Department of Nutrition Sciences Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7431-7869","authenticated-orcid":false,"given":"Mohammad Reza","family":"Shadmand Foumani Moghadam","sequence":"additional","affiliation":[{"name":"Service of Clinical Nutrition and Dietitian, Emam Reza Hospital Mashhad University of Medical Sciences Mashhad Iran"},{"name":"Health Technology Incubator Center, Bu\u2010Ali Research Institute Mashhad University of Medical Science Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6526-8712","authenticated-orcid":false,"given":"Mostafa","family":"Shahraki Jazinaki","sequence":"additional","affiliation":[{"name":"Department of Nutrition Sciences Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arezoo","family":"Rastegarmoghadam\u2010Ebrahimian","sequence":"additional","affiliation":[{"name":"Department of Nutrition Varastegan Institute for Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Amin","family":"Senobari","sequence":"additional","affiliation":[{"name":"Department of Nutrition Sciences Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazem","family":"Eslami","sequence":"additional","affiliation":[{"name":"Service of Clinical Nutrition and Dietitian, Emam Reza Hospital Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hassan","family":"Jokar","sequence":"additional","affiliation":[{"name":"Rheumatic Diseases Research Center, School of Medicine Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3585-9854","authenticated-orcid":false,"given":"Reza","family":"Rezvani","sequence":"additional","affiliation":[{"name":"Department of Nutrition Sciences Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11102392"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11216535"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","unstructured":"C. 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