{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:02:03Z","timestamp":1789984923336,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Sarcopenia is a prevalent and debilitating complication in patients with liver cirrhosis, contributing to poor clinical outcomes. Although diet quality is believed to influence muscle health, the role of overall dietary patterns in patients with cirrhosis remains inadequately explored. This study examined the relationship between dietary patterns and sarcopenia in individuals with liver cirrhosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross\u2010sectional study, 92 adults with clinically confirmed liver cirrhosis were enrolled from a tertiary academic center between February 2024 and January 2025. Standardized protocols were used to collect sociodemographic data, anthropometric measurements, physical activity data, and dietary intake information. Principal component analysis identified major dietary patterns based on a validated 168\u2010item food frequency questionnaire. Sarcopenia was diagnosed using AWGS 2019 criteria, incorporating mid\u2010upper arm circumference, handgrip strength, and the 6\u2010min walk test. Multivariable logistic regression models examined associations between dietary patterns and sarcopenia, adjusting for age, sex, energy intake, physical activity, and comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sarcopenia was identified in 66.3% of participants. Patients with sarcopenia exhibited significantly lower BMI, mid\u2010arm and calf circumference, and physical performance compared to their non\u2010sarcopenic counterparts (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Adherence to a Western dietary pattern, characterized by high intake of red and processed meats, refined grains, and fried foods, was positively associated with sarcopenia (adjusted OR for second tertile: 5.99; 95% CI: 1.53\u201323.43). Conversely, higher adherence to a healthy dietary pattern, rich in vegetables, nuts, oils, and whole grains, was inversely associated with sarcopenia (adjusted OR for the highest tertile: 0.35; 95% CI: 0.11\u20131.52).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings highlight the potential of dietary pattern modification as a strategy for preventing sarcopenia in cirrhotic patients. Integrating nutritional screening and dietary counseling into routine hepatology care may offer a low\u2010risk, cost\u2010effective approach to improving functional outcomes in this high\u2010risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72610","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T04:39:33Z","timestamp":1781239173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Dietary Patterns and Sarcopenia in Patients With Liver Cirrhosis: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"given":"Elham","family":"Sobhrakhshankhah","sequence":"first","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvin","family":"Hassanzadeh","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soghra","family":"Karimi","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen Reza","family":"Mansoorian","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naemeh","family":"Kolahdoozan","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"},{"name":"Department of Internal Medicine, School of Medicine, Firoozgar General Hospital Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6249-2520","authenticated-orcid":false,"given":"Azam","family":"Doustmohammadian","sequence":"additional","affiliation":[{"name":"Gastrointestinal and Liver Diseases Research Center Iran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-023-02832-1"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032016000400008"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-019-01605-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-26711-6.00032-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13586"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.11086"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-025-01028-y"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.011718"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2024.01.017"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2025.1596300"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2024.112613"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-48955-z"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-022-03525-2"},{"key":"e_1_2_11_15_1","doi-asserted-by":"crossref","unstructured":"J. I.Cleeman \u201cExecutive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) \u201d (National Heart Lung and Blood Institute 2001).","DOI":"10.1001\/jama.285.19.2486"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-15700-0"},{"key":"e_1_2_11_17_1","volume-title":"WHO STEPS Surveillance Manual: The WHO STEPwise Approach to Chronic Disease Risk Factor Surveillance\/Noncommunicable Diseases and Mental Health","author":"World Health Organization","year":"2005"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11071262"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113637"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v13.i11.1791"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2011.04.014"},{"issue":"8","key":"e_1_2_11_23_1","first-page":"1073","article-title":"The Iranian Version of International Physical Activity Questionnaire (IPAQ) in Iran: Content and Construct Validity, Factor Structure, Internal Consistency and Stability","volume":"18","author":"Moghaddam M. B.","year":"2012","journal-title":"World Applied Sciences Journal"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.114.208785"},{"key":"e_1_2_11_25_1","first-page":"42","article-title":"The Manual for Household Measures, Cooking Yields Factors and Edible Portion of Foods","volume":"7","author":"Ghaffarpour M.","year":"1999","journal-title":"Tehran Nashre Olume Keshavarzy"},{"key":"e_1_2_11_26_1","unstructured":"\u201cU.S. Department of Agriculture Agricultural Research Service \u201d (2011). USDA National Nutrient Database for Standard Reference Release 24 https:\/\/www.ars.usda.gov\/nutrientdata."},{"key":"e_1_2_11_27_1","volume-title":"Food Composition Table of Iran","author":"Azar M.","year":"1980"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12937-020-00580-6"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0067"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29367"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.34172\/aim.2021.06"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041433-200202000-00002"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-021-01612-z"},{"issue":"2","key":"e_1_2_11_34_1","first-page":"71","article-title":"Dietary Pattern Analysis: A New Approach to Identify Diet\u2010Disease Relations","volume":"2","author":"Esmaillzadeh A.","year":"2007","journal-title":"Iranian Journal of Nutrition Sciences and Food Technology"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.4135\/9781412984256"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.06.024"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2020.1810563"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155357"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32049"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15122749"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12144693"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/cdn\/nzac001"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.921415"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8111926"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-2803.202100000-43"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v30.i8.956"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.14740\/gr1707"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.72610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.72610","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.72610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T09:13:52Z","timestamp":1789982032000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.72610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/hsr2.72610"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.72610","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-07-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72610"}}