{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:54:04Z","timestamp":1790927644117,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Anxiety disorders are the most common mental health disorders worldwide that affect daily activities. These disorders are currently the second leading cause of mental health\u2010related disability globally. This study aimed to investigate the patterns and trends of anxiety disorders in Iranian provinces from 2010 to 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An ecological study was conducted using data from the IHME site over 12 years, from 2010 to 2021. The annual age\u2010standardized incidence rates of anxiety were calculated as expressed per 100,000 individuals, both globally and specifically for Iran. A Spatial\u2010Temporal Analysis assessed these rates' geographical and temporal distribution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 2010 to 2021, the ASR of anxiety in Iran was increased by 175.96 per 100,000 population (from 966.061 per 100,000 in 2010 to 1142.02 per 100,000 in 2021), which is higher than global trends. Iranian females experienced a higher incidence rate than males. Spatial analysis shows that southeastern provinces such as Kohgiluyeh and Boyer\u2010Ahmad and Sistan and Baluchestan have the highest incidence in both sexes. Based on the local Moran index, from 2010 to 2015, Kohgiluyeh and Boyer\u2010Ahmad provinces were in the high\u2010low cluster, and Bushehr and Semnan were in the low\u2010high cluster. Between 2016 and 2021, North Khorasan province was identified as the anxiety hotspot. In addition, Kerman province was in the low\u2010high cluster for 12 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of spatial distribution and temporal trends can help in the targeted allocation of resources for the management and promotion of mental health, especially in high\u2010risk provinces.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72894","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:00:31Z","timestamp":1785304831000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Spatial\u2010Temporal Epidemiology of Anxiety Incidence Rates in Iran (2010\u20132021): An Ecological Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2108-9529","authenticated-orcid":false,"given":"Fatemeh","family":"Majdolashrafi","sequence":"first","affiliation":[{"name":"Safety Promotion and Injury Prevention Research Center, Research Institute for Health Sciences and Environment Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Department of Epidemiology, School of Public Health and Safety Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Delpisheh","sequence":"additional","affiliation":[{"name":"Safety Promotion and Injury Prevention Research Center, Research Institute for Health Sciences and Environment Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Department of Epidemiology, School of Public Health and Safety Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raha","family":"Davatgar","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health and Safety Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goljamal","family":"Jorjani","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health and Safety Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7339-4747","authenticated-orcid":false,"given":"Aram","family":"Halimi","sequence":"additional","affiliation":[{"name":"Research Center for Social Determinants of Health, Research Institute for Metabolic and Obesity Disorders, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences Tehran 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