{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:41:45Z","timestamp":1791517305748,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Acute Type A aortic dissection (ATAAD) is a surgical emergency in which delays in diagnosis, transfer, and operative activation increase mortality and organ damage. Artificial intelligence (AI) may support earlier recognition, faster imaging interpretation, and more efficient multidisciplinary communication. This narrative review evaluates whether AI could shorten diagnostic and surgical timelines in ATAAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Literature Search and Study Selection<\/jats:title>\n                    <jats:p>\n                      This narrative review was informed by a structured literature search of PubMed\/MEDLINE, PubMed Central, Google Scholar, and professional society websites from database inception to 30 June 2026. Search terms included \u201cacute type A aortic dissection,\u201d \u201cacute aortic syndrome,\u201d \u201cartificial intelligence,\u201d \u201cmachine learning,\u201d \u201cdeep learning,\u201d \u201ccomputed tomography angiography,\u201d \u201cnon\u2010contrast CT,\u201d \u201cchest radiography,\u201d \u201celectrocardiography,\u201d \u201c\n                      <jats:sc>d<\/jats:sc>\n                      \u2010dimer,\u201d \u201cworkflow,\u201d \u201ctriage,\u201d \u201csurgical delay,\u201d and \u201cinterhospital transfer.\u201d We included peer\u2010reviewed original studies, systematic reviews, narrative reviews, and guideline documents that addressed AI\u2010enabled diagnosis, imaging interpretation, triage, transfer, multidisciplinary notification, or surgical pathway coordination in ATAAD or AAS. Abstract\u2010only reports, non\u2010clinical technical studies without dissection\u2010specific evaluation, and studies without clear diagnostic or workflow relevance were not used as primary evidence. Reference lists of relevant articles were manually screened. Because many AI studies enroll broader AAS cohorts, evidence was classified as ATAAD\u2010specific, AAS\u2010based with ATAAD applicability, or adult cardiovascular AI workflow extrapolation. AAS\u2010based findings were used only when their mechanism could plausibly affect ATAAD pathways, such as faster CT interpretation or automated urgent notification, and the limitations of applying these findings to ATAAD are stated throughout the manuscript.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A narrative literature review was conducted using PubMed\/MEDLINE, PubMed Central, Google Scholar, and professional society sources from database inception to 30 June 2026. We included peer\u2010reviewed studies, guidelines, and workflow evaluations relevant to AI\u2010assisted recognition, imaging, triage, and communication in ATAAD or acute aortic syndrome (AAS). Evidence specific to ATAAD was prioritized. AAS studies were interpreted cautiously when ATAAD\u2010specific data were unavailable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AI models using clinical variables, biomarkers, electrocardiography, chest radiography, non\u2010contrast CT, and CT angiography report AUC values of approximately 0.86 to 0.99, with many imaging models reporting sensitivities of 91%\u201397% and specificities near 93%\u201399%. Automated CT triage can identify suspected dissections within seconds and simulated workflows show 26%\u201343% reductions in scan\u2010to\u2010report intervals. Real\u2010world non\u2010contrast CT screening reduced diagnostic time in initially missed AAS cases from approximately 220\u2009min to 62\u2009min. However, most evidence derives from retrospective cohorts, simulated workflows, or AAS populations rather than prospective ATAAD surgical pathway studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AI may reduce key diagnostic and communication delays in ATAAD care, but direct evidence that it reduces door\u2010to\u2010surgery time or mortality remains limited. Prospective implementation studies are needed before AI\u2010enabled ATAAD pathways can be considered evidence\u2010based standards of care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.72906","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T06:25:42Z","timestamp":1785047142000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Time Is Aorta: Can Artificial Intelligence Improve Surgical Timelines in Acute Type A Aortic Dissection? 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UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5162-3644","authenticated-orcid":false,"given":"Riyaz","family":"Somani","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospitals of Leicester NHS Trust, Glenfield Hospital Leicester UK"},{"name":"Department of Cardiovascular Sciences, Clinical Science Wing University of Leicester, Glenfield Hospital Leicester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0107-4146","authenticated-orcid":false,"given":"Mokhtar","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospitals of Leicester NHS Trust, Glenfield Hospital Leicester UK"},{"name":"Department of Cardiovascular Sciences, Clinical Science Wing University of Leicester, Glenfield Hospital Leicester 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