{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:55:46Z","timestamp":1791186946534,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100015723","name":"Universit\u00e9 Clermont-Auvergne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100015723","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Localizing non\u2010palpable cancerous lesions of breast\u2010conserving surgery is a major challenge. Augmented reality (AR) and 3D imaging are emerging tools for surgical guidance. This study evaluates the feasibility of a noninvasive intraoperative localization technique using AR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective, interventional, single\u2010center proof\u2010of\u2010concept study investigates AR\u2010assisted localization of non\u2010palpable breast lesions. Secondary objectives include surgical time assessment, breast phantom development, and fusion feasibility between supine 3D breast MRI images and post\u2010MRI ultrasound with target lesion detection. The study includes an additional MRI in supine position and intraoperative 3D images of the patient's chest captured with a 3D camera. A 3D reconstruction of the patient's chest and lesions will be performed from the MRI images, called the preoperative 3D model. A total of five patients eligible for assessment are expected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The challenge of this study is the development of a noninvasive intraoperative localization technique using AR from preoperative images in breast\u2010conserving surgery. If this study is successful, a randomized trial will be designed to compare the accuracy of the intraoperative localization technique using AR with that of the gold standard intraoperative breast ultrasound.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73096","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:36:24Z","timestamp":1787808984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Study Protocol for Assessment of the Feasibility of an Intraoperative Localization Technique Using Augmented Reality in Breast\u2010Conserving Surgery for Non\u2010Palpable Cancer Lesions: A Feasibility Study"],"prefix":"10.1002","volume":"9","author":[{"given":"Alexia","family":"Giro","sequence":"first","affiliation":[{"name":"Division de Recherche Clinique, D\u00e9l\u00e9gation Recherche Clinique &amp; Innovation, Centre Jean Perrin Centre de Lutte contre le Cancer Clermont\u2010Ferrand France"},{"name":"INSERM U1240 IMoST University of Clermont Auvergne Clermont\u2010Ferrand France"},{"name":"UMR 501, Clinical Investigation Centre Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3575-7260","authenticated-orcid":false,"given":"Judith","family":"Passildas","sequence":"additional","affiliation":[{"name":"Division de Recherche Clinique, D\u00e9l\u00e9gation Recherche Clinique &amp; 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