{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:55:56Z","timestamp":1791186956023,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mindfulness\u2010Based Relapse Prevention (MBRP) combines mindfulness practice with relapse\u2010prevention strategies and has demonstrated efficacy in improving psychological well\u2010being among individuals with substance use disorders. This pilot study evaluated quality\u2010of\u2010life changes following an audio\u2010based mobile MBRP application delivered as an adjunct to methadone maintenance treatment (MMT) among individuals with opioid use disorder (OUD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This single\u2010arm before\u2013after study included 14 male participants with OUD receiving MMT at two addiction treatment clinics. Participants used the MBRP application for 8 weeks alongside routine care. Quality of life was assessed using the SF\u201036 at baseline, post\u2010intervention, and 3\u2010month follow\u2010up. Session completion was monitored through weekly clinician\u2010verified contacts. Substance use and relapse status were monitored descriptively as secondary clinical indicators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean SF\u201036 scores increased from 40.34\u2009\u00b1\u200911.26 at baseline to 66.57\u2009\u00b1\u200913.39 post\u2010intervention and remained above baseline at follow\u2010up (57.76\u2009\u00b1\u200910.89). Significant improvements were observed from baseline to post\u2010intervention (mean difference = 26.23, 95% CI: 17.73\u201334.73,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, Cohen's\n                      <jats:italic>d<\/jats:italic>\n                      z\u2009=\u20091.78) and from baseline to follow\u2010up (mean difference = 17.42, 95% CI: 11.84\u201322.99,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, Cohen's\n                      <jats:italic>d<\/jats:italic>\n                      z\u2009=\u20091.80). Session\u2010completion rate was 92.9% (mean = 7.43 sessions per participant). At follow\u2010up, 11 participants (78.6%) remained free of documented illicit opioid use; three (21.4%) had documented relapse events, reported descriptively given the uncontrolled design.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Participation in the mobile MBRP application was associated with quality\u2010of\u2010life improvements remaining above baseline at 3\u2010month follow\u2010up, supporting feasibility in routine addiction\u2010treatment settings. Randomized controlled trials with addiction\u2010specific outcomes, standardized acceptability instruments, and objective engagement analytics are needed to establish effectiveness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73103","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T11:26:25Z","timestamp":1787743585000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Smartphone\u2010Delivered MBRP and Quality of Life among Individuals With Opioid Use Disorder: A Pilot Before\u2013After Study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4282-5311","authenticated-orcid":false,"given":"Shadi","family":"Dashtbani","sequence":"first","affiliation":[{"name":"Department of Health Information Technology Varastegan Institute for Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9546-309X","authenticated-orcid":false,"given":"Hadi","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of Psychology and Education of Exceptional Children, School of Psychology and Educational Sciences Allameh Tabatabaei University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9734-9126","authenticated-orcid":false,"given":"Narges","family":"Norouzkhani","sequence":"additional","affiliation":[{"name":"Department of Health Information Technology, School of Management and Medical Informatics Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Saghebi","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, School of Medicine Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4765-1957","authenticated-orcid":false,"given":"Atefeh","family":"Khoshkangin","sequence":"additional","affiliation":[{"name":"Department of Health Information Technology Varastegan Institute for Medical Sciences Mashhad Iran"},{"name":"Department of Medical Informatics, School of Medicine Mashhad University of Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8096-2530","authenticated-orcid":false,"given":"Mohammad Reza","family":"Mazaheri Habibi","sequence":"additional","affiliation":[{"name":"Department of Health Information Technology Varastegan Institute for Medical Sciences Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"issue":"32","key":"e_1_2_13_2_1","first-page":"87","article-title":"The Effectiveness of Mindfulness\u2010Based Relapse Prevention on the Prevention of Relapse, Craving, and Self\u2010Control in Opiate\u2010Dependent Individuals","volume":"8","author":"Maredpour A.","year":"2012","journal-title":"Quarterly Journal of Research on Addiction"},{"key":"e_1_2_13_3_1","volume-title":"Principles of Addiction: Comprehensive Addictive Behaviors and Disorders","author":"Miller P. M.","year":"2013"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-018-0180-x"},{"key":"e_1_2_13_5_1","unstructured":"H.DejakamAddiction Treatment Appropriate Solutions. [in Persian].Congress60.org. Received on April 18."},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13989"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.119.259408"},{"key":"e_1_2_13_8_1","article-title":"Information Requirements of a Mobile\u2010Based System for Managing the Treatment of Patients with Stimulant Abuse","author":"Ghazi Saeedi M.","year":"2019","journal-title":"Journal of Paramedical School of Tehran University of Medical Sciences"},{"issue":"4","key":"e_1_2_13_9_1","first-page":"250","article-title":"Effectiveness of Mindfulness\u2010Based Relapse Prevention on Quality of Life and Craving in Methadone\u2010Treated Patients: A Randomized Clinical Trial","volume":"10","author":"Yaghubi M.","year":"2018","journal-title":"Addiction & Health"},{"key":"e_1_2_13_10_1","first-page":"1","article-title":"The Effectiveness of Mindfulness\u2010Based Relapse Prevention Intervention on Substance Abuse and the Severity of Symptoms of Depression and Comorbid Anxiety in Addicts in a Therapeutic Community","volume":"1","author":"Zemestani M.","year":"2016","journal-title":"Research on Addiction"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13722-018-0115-3"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-004-1014-5"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-9-4"},{"key":"e_1_2_13_14_1","volume-title":"Mindfulness\u2010Based Relapse Prevention for Addictive Behaviors","author":"Bowen S.","year":"2021"},{"key":"e_1_2_13_15_1","unstructured":"P.Jnod S.Mohammadkhani F. M.Shirmahaleh M. H. Z.Tagvaei andP.Peyvandi \u201cThe Effectiveness of Mindfulness\u2010Based Relapse Prevention Treatment in Improving the Symptoms of Addiction and Negative Emotions in Men With Methamphetamine Dependence \u201dJournal of Mashhad University of Medical Sciences. [in Persian]."},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6947-12-67"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2015.06.003"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/TIN.0000000000000290"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.2147\/AHMT.S200801"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/jehp.jehp_1188_22"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.30699\/fhi.v11i1.373"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-023-06206-z"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-024-01785-2"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-022-01912-8"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.30699\/fhi.v10i1.316"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.1156"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.30699\/fhi.v13i0.572"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.30699\/fhi.v11i1.346"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2024.2315228"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1037\/ccp0000940"},{"key":"e_1_2_13_31_1","first-page":"141","volume-title":"Mindfulness\u2010Based Treatment Approaches","author":"Bowen S.","year":"2014"},{"key":"e_1_2_13_32_1","first-page":"1","article-title":"Effectiveness of Mindfulness Treatment on Quality of Life in Opium Abusers: Promotion of the Mental and Physical Health","volume":"2","author":"Habibi M.","year":"2013","journal-title":"Quarterly Journal of Health Psychology"},{"key":"e_1_2_13_33_1","doi-asserted-by":"crossref","unstructured":"J. A.Brewer H. M.Elwafi andJ. H.Davis \u201cCraving to Quit: Psychological Models and Neurobiological Mechanisms of Mindfulness Training as Treatment for Addictions.\u201dPsychology of Addictive Behaviors27 no.2(2013):369\u2013379.","DOI":"10.1037\/a0028490"},{"key":"e_1_2_13_34_1","first-page":"107","article-title":"Emotion Regulation as a Mechanism of Change in Acceptance\u2010and Mindfulness\u2010Based Treatments","volume":"2","author":"Gratz K. L.","year":"2010","journal-title":"Assessing Mindfulness and Acceptance Processes In Clients: Illuminating the Theory and Practice of Change"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.73103","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:42:42Z","timestamp":1791186162000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.73103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":33,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/hsr2.73103"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.73103","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"assertion":[{"value":"2025-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73103"}}