{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:55:14Z","timestamp":1791186914672,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Type 1 diabetes mellitus (T1DM) is a chronic condition that affects emotional, physical, social, and academic functioning of children and adolescents. Assessing health\u2010related quality of life (HRQoL) provides insight into the broader impact of T1DM. This study evaluated HRQoL among pediatric patients with T1DM in southwest Iran using reports from children and parents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study included 234 children aged 5\u201316 years with T1DM and their parents at Abuzar Hospital (Ahvaz, Iran). HRQoL was assessed using the Pediatric Quality of Life Inventory (PedsQL) version 4.0 completed by both children and parents, and the PedsQL 3.2 Diabetes Module. Demographic, clinical, and lifestyle characteristics were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Children reported the highest scores for physical functioning and the lowest scores for school functioning. Parents rated their children's HRQoL significantly lower than children did across all domains (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Boys had significantly\u00a0higher HRQoL than girls in all generic domains except school functioning and in all diabetes\u2010specific domains (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Children reported higher HRQoL than adolescents, with significant differences in most domains except physical functioning (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Common unhealthy behaviors included physical inactivity (31.6%), breakfast skipping (31.2%), and weekly fast\u2010food consumption (43.2%). Only 26.5% of participants consistently practiced carbohydrate counting. Multivariable linear regression analysis showed that male sex, regular physical activity, and consistent carbohydrate counting were independently associated with higher total PedsQL scores (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pediatric patients with T1DM in this study had the lowest HRQoL scores in school functioning. Differences between children's and parents' reports suggest that parents may perceive a greater impact of diabetes than children. Lower HRQoL among girls highlights the need for additional psychosocial support. Routine HRQoL assessment, psychosocial support, regular physical activity, carbohydrate counting education, and family\u2010centered care may improve overall well\u2010being in these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73143","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T06:35:18Z","timestamp":1788158118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Determinants of Health\u2010Related Quality of Life in Children and Adolescents With Type 1 Diabetes: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"given":"Solmaz","family":"Heidari","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz 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Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9157-1922","authenticated-orcid":false,"given":"Shooka","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz 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