{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:56:17Z","timestamp":1791186977397,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Prematurity remains a leading cause of neonatal morbidity and mortality worldwide, with the highest burden in low\u2010resource settings such as sub\u2010Saharan Africa. Reliable local data are limited in Sudan, particularly in Eastern states. This study aimed to determine the incidence, maternal risk factors, neonatal characteristics, and outcomes of premature infants admitted to the NICU at Gadarif Teaching Hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective observational study was conducted from July 2024 to July 2025. Medical records of all neonates admitted to the NICU were reviewed. Preterm birth was defined as delivery before 37 completed weeks of gestation. Maternal, perinatal, and neonatal variables were extracted. Logistic regression models were used to identify predictors of preterm birth and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 604 neonates, 198 (32.8%) were preterm. Mothers of preterm infants were younger (24.3\u2009\u00b1\u20096.5 vs. 26.4\u2009\u00b1\u20096.6 years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Elective cesarean delivery and lower parity were associated with prematurity. Pre\u2010eclampsia was significantly more common among preterm births (4.0% vs. 1.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.049). Preterm neonates had markedly lower mean birth weight (1.7\u2009\u00b1\u20092.4\u2009kg vs. 3.0\u2009\u00b1\u20091.6\u2009kg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and higher rates of sepsis (71.7%), respiratory distress (62.6%), and jaundice (24.7%). Mortality was significantly higher among preterm infants compared to term (29.4% vs. 7.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In multivariable analysis, younger maternal age increased risk of prematurity, while higher gestational age (aOR 0.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) and antenatal care attendance (aOR 0.26,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032) reduced mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Prematurity constituted nearly one\u2010third of NICU admissions in this cohort and was associated with high mortality. Strengthening antenatal care, delaying early pregnancies, and improving NICU capacity may reduce the burden of preterm related deaths in this setting, although further studies are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73177","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:20:55Z","timestamp":1788326455000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence and Clinical Outcomes of Premature Infants: 1\u2010Year Retrospective Study at the NICU of Gadarif Teaching Hospital"],"prefix":"10.1002","volume":"9","author":[{"given":"Mohammed Ahmed Abdellah","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Pediatric, College of Medicine, King Saud University Celiac Disease Research Chair King Saud University Riyadh Saudi Arabia"},{"name":"Faculty of Medicine and Health Sciences University of Gadarif Gadarif Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3894-0378","authenticated-orcid":false,"given":"Elshazaly","family":"Saeed","sequence":"additional","affiliation":[{"name":"Department of Pediatric, College of Medicine, King Saud University Celiac Disease Research Chair King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0109-7331","authenticated-orcid":false,"given":"Elnazeir Mohamed Ibrahim","family":"Mohamedzain","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences University of Gadarif Gadarif Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Salah Abdulrazeg","family":"Abdulrahman","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Alzaiem Alazhari University Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9834-1175","authenticated-orcid":false,"given":"Suleman Sofian","family":"Suliman","sequence":"additional","affiliation":[{"name":"Faculty of Medicine National University Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Mohammed Ahmed","family":"Abdellah","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Khartoum Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. L. Sir Ahmed Addalla","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology New Halfa Hospital New Halfa Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2824-4642","authenticated-orcid":false,"given":"Sohaib Mohammed Mokhtar","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences University of Gadarif Gadarif Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00878-4"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2022.1622"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-025-02033-x"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13195"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph191710537"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-021-04233-2"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2024.102518"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2303347"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0276793"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000365798"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2021.01.004"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0803267"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2011.0376"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641955.2016.1190846"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-59465-x"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40348-017-0070-1"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0965539508002222"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.15547\/10.15547\/bjvm.2012"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.17743"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx125"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004409"}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73177","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.73177","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:45:00Z","timestamp":1791186300000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.73177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/hsr2.73177"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.73177","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2025-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73177"}}