{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:56:02Z","timestamp":1791186962579,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Antimicrobial Background: Antimicrobial resistance (AMR) is a major global health challenge driven largely by inappropriate antimicrobial use. Nurses play a critical role in antimicrobial stewardship, infection prevention, and patient education, yet gaps between knowledge and practice persist, particularly in low\u2010resource settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study assessed the knowledge, attitudes, and practices (KAP) of nurses regarding AMR in selected hospitals within the Tamale metropolis, Ghana.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A descriptive cross\u2010sectional study was conducted among nurses across three hospitals using a convenience sampling approach. Data were collected using a structured questionnaire and analyzed using Statistical Package for Social Sciences (SPSS) version 21. Descriptive statistics were used to summarize variables, and inferential analysis (\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test, and regression) was used to assess associations. Statistical significance was set at\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 610 nurses approached, 384 completed the questionnaire (response rate: 73.3%). All respondents (100%) had heard of AMR, with 78% identifying the hospital as their main source of information. A majority demonstrated good knowledge of AMR, with key contributors identified as poor infection control practices (67%), improper antibiotic prescribing (59%), and use of broad\u2010spectrum antibiotics (76%). Overall, 83% of respondents demonstrated good knowledge (mean score: 11.9\u2009\u00b1\u20090.11). Positive attitudes toward antimicrobial stewardship were observed in 78% of participants. Educational level was significantly associated with attitudes toward antibiotic use (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022), although the correlation was weak. In practice, 57% of respondents reported that patient demand contributes to inappropriate antibiotic use, while 19% did not recognize that unnecessary antibiotic administration promotes resistance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nurses demonstrated good knowledge and generally positive attitudes toward AMR; however, important gaps remain in stewardship\u2010related practices. Strengthening institutional antimicrobial stewardship programs and continuous professional education is essential to improve practice and mitigate the growing threat of AMR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73249","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:07:07Z","timestamp":1789535227000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Knowledge, Attitude, and Practices of Nurses on Antimicrobial Resistance"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9940-4492","authenticated-orcid":false,"given":"Abilba Frieda","family":"Ayinema","sequence":"first","affiliation":[{"name":"Pharmacy Department Tamale Teaching Hospital Tamale Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2602-1558","authenticated-orcid":false,"given":"Jamal\u2010deen I.","family":"Tiiba","sequence":"additional","affiliation":[{"name":"Pharmacology, Therapeutics and Pharmacovigilance Department Nurses' and Midwives' Training College Tamale Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4287-856X","authenticated-orcid":false,"given":"Cynthia Amaning","family":"Danquah","sequence":"additional","affiliation":[{"name":"Pharmacology Department, Faculty of Pharmaceutical Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7944-2255","authenticated-orcid":false,"given":"Kwame Ohene","family":"Buabeng","sequence":"additional","affiliation":[{"name":"Pharmacology Department, Faculty of Pharmaceutical Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana"},{"name":"Clinical Pharmacy Department, Faculty of Pharmaceutical Sciences University of Health and Allied Sciences Ho Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"e_1_2_16_2_1","unstructured":"World Health Organization (WHO) Global Action Plan on Antimicrobial Resistance(WHO 2015)."},{"key":"e_1_2_16_3_1","unstructured":"J.O'Neill Tackling Drug\u2010Resistant Infections Globally: Final Report and Recommendations(2016)."},{"key":"e_1_2_16_4_1","unstructured":"M. J.Newman E.Frimpong A.Asamoah\u2010Adu andE.Sampene\u2010Donkor \u201cResistance to Antimicrobial Drugs in Ghana. The Ghanaian\u2010Dutch Collaboration for Health Research and Development \u201d Project Number 2001\/GD\/07. Technical Report Series No. 5 (2006):8\u201326."},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1757177410389627"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-017-0208-x"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv164"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3199-1"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-019-0303-3"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S88725"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089716"},{"key":"e_1_2_16_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-018-3377-7"},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu543"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.08.026"},{"key":"e_1_2_16_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/2282703"},{"key":"e_1_2_16_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-018-2899-y"},{"key":"e_1_2_16_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4210-1"},{"key":"e_1_2_16_18_1","unstructured":"Centers for Disease Control and Prevention (CDC) Antibiotic Resistance Threats Report(CDC 2019)."}],"container-title":["Health Science Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/hsr2.73249","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hsr2.73249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:40:51Z","timestamp":1791186051000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hsr2.73249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/hsr2.73249"],"URL":"https:\/\/doi.org\/10.1002\/hsr2.73249","archive":["Portico"],"relation":{},"ISSN":["2398-8835","2398-8835"],"issn-type":[{"value":"2398-8835","type":"print"},{"value":"2398-8835","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2025-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e73249"}}