{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T04:40:27Z","timestamp":1792384827459,"version":"4.4.0"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Health Science Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Generic prescribing is a cornerstone of sustainable healthcare delivery, yet provider preference for brand\u2010name pharmaceuticals remains a widespread challenge in resource\u2010limited settings. This study evaluated brand\u2010name prescribing practices and identified independent predictor domains among healthcare prescribers at Asella Referral and Teaching Hospital (ARTH), Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A facility\u2010based cross\u2010sectional study was conducted between August and October 2024, involving a census of 229 prescribers. Data were collected using structured, pretested questionnaires. Key domain scores were operationalized as continuous composite variables (1\u20135 Likert\u2010type scale) to maintain data integrity. A multivariable linear regression model was estimated to identify independent associates of brand\u2010prescribing practice following verification of classical regression assumptions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Prescribers demonstrated high objective awareness of generic policies and drug efficacy (domain agreement of 76.0%); however, non\u2010adherence to generic\u2010favouring practices was reported by 54.2% of respondents, illustrating a marked knowledge\u2010practice gap. The overall linear regression model was statistically significant (\n                      <jats:italic>F<\/jats:italic>\n                      (6, 222)\u2009=\u200944.424,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001, Adjusted\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.533). Positive Perception of Brand Drugs (standardized\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.416,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and Work Experience (standardized\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.398,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) emerged as the only significant independent predictors. Policy knowledge, pharmaceutical promotion, and patient factors did not retain statistical significance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A clear divergence exists between regulatory policy knowledge and routine prescribing practices. Brand\u2010name prescribing demonstrated significant positive independent associations with internalized provider perceptions and clinical tenure. Hospital leadership and policymakers should complement policy dissemination with targeted interventions addressing provider perceptions and clinical habit formation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hsr2.73384","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T07:12:36Z","timestamp":1791961956000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Knowledge\u2010Practice Gap in Prescribing: A Study of Perceptual and Experiential Predictors at Asella Referral and Teaching Hospital, Ethiopia\u2014A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"9","author":[{"given":"Olana","family":"Daba","sequence":"first","affiliation":[{"name":"Department of Pediatrics, College of Health Sciences Arsi University Asella Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tesfa","family":"Gebremeskel","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Health Sciences Arsi University Asella Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdurrahman","family":"Kalu","sequence":"additional","affiliation":[{"name":"Department of Public Health, College of Health Sciences Arsi University Asella Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7240-7238","authenticated-orcid":false,"given":"Ayalneh","family":"Demissie","sequence":"additional","affiliation":[{"name":"Department of Public Health, College of Health Sciences Arsi University Asella Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_2_17_2_1","volume-title":"Access to Essential Medicines: A Human Right","author":"World Health Organization","year":"2017"},{"key":"e_1_2_17_3_1","volume-title":"Promoting Rational Use of Medicines: Core Components","author":"World Health Organization","year":"2002"},{"key":"e_1_2_17_4_1","volume-title":"Food and Drug Administration. Generic Drug Facts","author":"U.S","year":"2024"},{"key":"e_1_2_17_5_1","volume-title":"The Role of Pharmacovigilance in Rational Use of Medicines","author":"World Health Organization","year":"2016"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.4081\/jphia.2019.894"},{"key":"e_1_2_17_7_1","volume-title":"Good Prescribing Manual for Ethiopia","author":"Ethiopian Food and Drug Authority","year":"2018"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40545-017-0103-6"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.18203\/2319-2003.ijbcp20191580"},{"key":"e_1_2_17_10_1","volume-title":"Rational Prescribing: Principles and Practice","author":"British Pharmacological Society","year":"2020"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c2898"},{"key":"e_1_2_17_12_1","volume-title":"Vulnerable Populations in the United States","author":"Shi 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Prescribing Practice Toward Generic Drugs","volume":"7","author":"Ms A.\u2010G.","year":"2018","journal-title":"Journal of Basic and Clinical Pharmacy"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.18203\/2319-2003.ijbcp20172215"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-017-2565-x"},{"key":"e_1_2_17_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204146"},{"key":"e_1_2_17_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/1741134317728420"},{"key":"e_1_2_17_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0000000000000096"},{"key":"e_1_2_17_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sapharm.2018.03.064"},{"key":"e_1_2_17_29_1","volume-title":"Generic and Brand Name Medicines","author":"National Health Service"},{"issue":"2","key":"e_1_2_17_30_1","first-page":"210","article-title":"Attitudes and Perceptions Towards Generic Medicines Among Undergraduate Medical Students","volume":"30","author":"Abasiama O.","year":"2015","journal-title":"International Journal of Pharmaceutical Sciences Review and Research"},{"key":"e_1_2_17_31_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1415016"},{"issue":"2","key":"e_1_2_17_32_1","first-page":"78","article-title":"Generic Drug Products and Their Role in Reducing Healthcare Costs","volume":"1","author":"Dunets A.","year":"2020","journal-title":"Econ J"},{"key":"e_1_2_17_33_1","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8598.153818"},{"key":"e_1_2_17_34_1","volume-title":"Generic Drugs: Questions and Answers","author":"U.S. Food and Drug Administration","year":"2024"}],"container-title":["Health Science 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