{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:08:22Z","timestamp":1774645702265,"version":"3.50.1"},"reference-count":25,"publisher":"Hindawi Limited","issue":"1","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2434,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Mutat."],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1002\/humu.20827","type":"journal-article","created":{"date-parts":[[2008,8,19]],"date-time":"2008-08-19T18:07:13Z","timestamp":1219169233000},"page":"85-92","source":"Crossref","is-referenced-by-count":81,"title":["Glial Cells Missing-2 (GCM2) transactivates the calcium-sensing receptor gene: effect of a dominant-negative GCM2 mutant associated with autosomal dominant hypoparathyroidism"],"prefix":"10.1155","volume":"30","author":[{"given":"Lucie","family":"Canaff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Mosesova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.C.","family":"Cole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey N.","family":"Hendy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"10.1002\/humu.20827-BIB1","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1172\/JCI114811","article-title":"Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism","volume":"86","author":"Arnold","year":"1990","journal-title":"J Clin Invest"},{"key":"10.1002\/humu.20827-BIB2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/jmg.2004.026898","article-title":"Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism","volume":"42","author":"Baumber","year":"2005","journal-title":"J Med Genet"},{"key":"10.1002\/humu.20827-BIB3","doi-asserted-by":"crossref","first-page":"30337","DOI":"10.1074\/jbc.M201804200","article-title":"Human calcium-sensing receptor gene","volume":"277","author":"Canaff","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1002\/humu.20827-BIB4","doi-asserted-by":"crossref","first-page":"13586","DOI":"10.1074\/jbc.M708087200","article-title":"The proinflammatory cytokine, interleukin-6, up-regulates calcium-sensing receptor gene transcription via Stat1\/3 and Sp1\/3","volume":"283","author":"Canaff","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1002\/humu.20827-BIB5","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1093\/bioinformatics\/bti473","article-title":"MatInspector and beyond: promoter analysis based on transcription factor binding sites","volume":"21","author":"Cartharius","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1002\/humu.20827-BIB6","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1093\/emboj\/cdg182","article-title":"Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition","volume":"22","author":"Cohen","year":"2003","journal-title":"EMBO J."},{"key":"10.1002\/humu.20827-BIB7","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1046\/j.1365-2265.2002.01627.x","article-title":"Underexpression of Gcm2, a master regulatory gene of parathyroid gland development, in adenomas of primary hyperparathyroidism","volume":"57","author":"Correa","year":"2002","journal-title":"Clin Endocrinol"},{"key":"10.1002\/humu.20827-BIB8","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1172\/JCI200113180","article-title":"Familial isolated hypoparathyroidism caused by a mutation in the gene for the transcription factor GCMB","volume":"108","author":"Ding","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1002\/humu.20827-BIB9","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1210\/jc.87.3.1309","article-title":"Identification and functional characterization of novel calcium-sensing receptor mutations in familial hypocalciuric hypercalcemia and autosomal dominant hypocalcemia","volume":"87","author":"D'Souza-Li","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/humu.20827-BIB10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/35018111","article-title":"Genetic ablation of parathyroid glands reveals another source of parathyroid hormone","volume":"406","author":"Gunther","year":"2000","journal-title":"Nature"},{"key":"10.1002\/humu.20827-BIB11","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/B978-012098652-1\/50158-X","volume-title":"Principles of bone biology","author":"Hendy","year":"2002"},{"key":"10.1002\/humu.20827-BIB12","first-page":"1951","volume-title":"Principles and practice of medical genetics","author":"Hendy","year":"2007"},{"key":"10.1002\/humu.20827-BIB23","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/0092-8674(95)90281-3","article-title":"Glial cells missing: A binary switch between neuronal and glial determination in Drosophila","volume":"82","author":"Hosaya","year":"1995","journal-title":"Cell"},{"key":"10.1002\/humu.20827-BIB24","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0092-8674(95)90280-5","article-title":"Glial cells missing: A genetic switch that controls glial versus neuronal fate","volume":"82","author":"Jones","year":"1995","journal-title":"Cell"},{"key":"10.1002\/humu.20827-BIB13","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0014-5793(98)01650-0","article-title":"Isolation and expression analysis of a novel human homologue of the Drosophila gene glial cells missing (gcm) gene","volume":"442","author":"Kanemura","year":"1999","journal-title":"FEBS Lett"},{"key":"10.1002\/humu.20827-BIB25","doi-asserted-by":"crossref","first-page":"12364","DOI":"10.1073\/pnas.95.21.12364","article-title":"Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing","volume":"95","author":"Kim","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.20827-BIB14","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1210\/jc.2003-030733","article-title":"Expression of GCMB by intrathymic parathyroid hormone-secreting adenomas indicates their parathyroid cell origin","volume":"89","author":"Maret","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/humu.20827-BIB15","doi-asserted-by":"crossref","first-page":"17716","DOI":"10.1073\/pnas.0406116101","article-title":"The origin of the parathyroid gland","volume":"101","author":"Okabe","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.20827-BIB16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/ng0592-149","article-title":"A donor splice site mutation in the parathyroid hormone gene is associated with autosomal recessive hypoparathyroidism","volume":"1","author":"Parkinson","year":"1992","journal-title":"Nat Genet"},{"key":"10.1002\/humu.20827-BIB17","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/ng1194-303","article-title":"Autosomal dominant hypocalcemia caused by a Ca+-sensing receptor gene mutations","volume":"8","author":"Pollak","year":"1994","journal-title":"Nat Genet"},{"key":"10.1002\/humu.20827-BIB18","doi-asserted-by":"crossref","first-page":"4739","DOI":"10.1073\/pnas.94.9.4739","article-title":"The regulator of early gliogenesis glial cells missing is a transcription factor with a novel type of DNA-binding domain","volume":"94","author":"Schreiber","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.20827-BIB19","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1093\/nar\/26.10.2337","article-title":"Structural requirements for DNA binding of GCM proteins","volume":"26","author":"Schreiber","year":"1998","journal-title":"Nucleic Acid Res"},{"key":"10.1002\/humu.20827-BIB20","first-page":"3792","article-title":"A novel mutation of the preproparathyroid hormone gene associated with autosomal recessive familial isolated hypoparathyroidism","volume":"84","author":"Sunthornthepvarakul","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/humu.20827-BIB21","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1210\/jc.2004-2450","article-title":"GCMB mutation in familial isolated hypoparathyroidism with residual secretion of parathyroid hormone","volume":"90","author":"Thomee","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/humu.20827-BIB22","doi-asserted-by":"crossref","first-page":"4774","DOI":"10.1074\/jbc.275.7.4774","article-title":"Protein stability and domain topology determine the transcriptional activity of the mammalian glial cells missing homolog, GCMb","volume":"275","author":"Tuerk","year":"2000","journal-title":"J Biol Chem"}],"container-title":["Human Mutation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhumu.20827","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/humu.20827","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T16:51:58Z","timestamp":1672332718000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/humu.20827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"URL":"https:\/\/doi.org\/10.1002\/humu.20827","relation":{},"ISSN":["1059-7794","1098-1004"],"issn-type":[{"value":"1059-7794","type":"print"},{"value":"1098-1004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}