{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:09:16Z","timestamp":1761743356961},"reference-count":36,"publisher":"Hindawi Limited","issue":"7","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1932,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Mutat."],"DOI":"10.1002\/humu.21276","type":"journal-article","created":{"date-parts":[[2010,5,19]],"date-time":"2010-05-19T00:27:20Z","timestamp":1274228840000},"page":"875-885","source":"Crossref","is-referenced-by-count":14,"title":["SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region"],"prefix":"10.1155","volume":"31","author":[{"given":"Espen","family":"Melum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus B.","family":"Schilhabel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom H.","family":"Karlsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Rosenstiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Franke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2010,5,18]]},"reference":[{"key":"10.1002\/humu.21276-BIB1|cit1","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1038\/ng.175","article-title":"Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease","volume":"40","author":"Barrett","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/humu.21276-BIB2|cit2","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/nature07517","article-title":"Accurate whole human genome sequencing using reversible terminator chemistry","volume":"456","author":"Bentley","year":"2008","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB3|cit3","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/ng.f.136","article-title":"Common and rare variants in multifactorial susceptibility to common diseases","volume":"40","author":"Bodmer","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/humu.21276-BIB4|cit4","doi-asserted-by":"crossref","first-page":"19096","DOI":"10.1073\/pnas.0910672106","article-title":"Genetic diagnosis by whole exome capture and massively parallel DNA sequencing","volume":"106","author":"Choi","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.21276-BIB5|cit5","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/sj.ejhg.5200897","article-title":"Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations","volume":"11","author":"Croucher","year":"2003","journal-title":"Eur J Hum Genet"},{"key":"10.1002\/humu.21276-BIB6|cit6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jbiotec.2008.03.021","article-title":"The Genome Sequencer FLX System-longer reads, more applications, straight forward bioinformatics and more complete data sets","volume":"136","author":"Droege","year":"2008","journal-title":"J Biotechnol"},{"key":"10.1002\/humu.21276-BIB7|cit7","doi-asserted-by":"crossref","first-page":"e691","DOI":"10.1371\/journal.pone.0000691","article-title":"Systematic association mapping identifies NELL1 as a novel IBD disease gene","volume":"2","author":"Franke","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1002\/humu.21276-BIB8|cit8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nbt.1523","article-title":"Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing","volume":"27","author":"Gnirke","year":"2009","journal-title":"Nat Biotechnol"},{"key":"10.1002\/humu.21276-BIB9|cit9","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2144\/000113082","article-title":"Method for improving sequence coverage uniformity of targeted genomic intervals amplified by LR-PCR using Illumina GA sequencing-by-synthesis technology","volume":"46","author":"Harismendy","year":"2009","journal-title":"Biotechniques"},{"key":"10.1002\/humu.21276-BIB10|cit10","doi-asserted-by":"crossref","first-page":"R32","DOI":"10.1186\/gb-2009-10-3-r32","article-title":"Evaluation of next generation sequencing platforms for population targeted sequencing studies","volume":"10","author":"Harismendy","year":"2009","journal-title":"Genome Biol"},{"key":"10.1002\/humu.21276-BIB11|cit11","doi-asserted-by":"crossref","first-page":"9362","DOI":"10.1073\/pnas.0903103106","article-title":"Potential etiologic and functional implications of genome-wide association loci for human diseases and traits","volume":"106","author":"Hindorff","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.21276-BIB12|cit12","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/35079107","article-title":"Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease","volume":"411","author":"Hugot","year":"2001","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB13|cit13","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1086\/339432","article-title":"CARD15\/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease","volume":"70","author":"Lesage","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.1002\/humu.21276-BIB14|cit14","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1053\/j.gastro.2004.01.063","article-title":"Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences","volume":"126","author":"Loftus","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1002\/humu.21276-BIB15|cit15","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature03959","article-title":"Genome sequencing in microfabricated high-density picolitre reactors","volume":"437","author":"Margulies","year":"2005","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB16|cit16","article-title":"Reagents, methods, and libraries for bead-based sequencing","author":"McKernan","year":"2006","journal-title":"Patent"},{"key":"10.1002\/humu.21276-BIB17|cit17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrg2626","article-title":"Sequencing technologies-the next generation","volume":"11","author":"Metzker","year":"2010","journal-title":"Nat Rev Genet"},{"key":"10.1002\/humu.21276-BIB18|cit18","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1126\/science.1167728","article-title":"Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes","volume":"324","author":"Nejentsev","year":"2009","journal-title":"Science"},{"key":"10.1002\/humu.21276-BIB19|cit19","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nature08250","article-title":"Targeted capture and massively parallel sequencing of 12 human exomes","volume":"461","author":"Ng","year":"2009","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB20|cit20","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/35079114","article-title":"A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease","volume":"411","author":"Ogura","year":"2001","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB21|cit21","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/ng2061","article-title":"Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility","volume":"39","author":"Parkes","year":"2007","journal-title":"Nat Genet"},{"key":"10.1002\/humu.21276-BIB22|cit22","doi-asserted-by":"crossref","first-page":"14747","DOI":"10.1073\/pnas.0706645104","article-title":"Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci","volume":"104","author":"Raelson","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.21276-BIB23|cit23","first-page":"365","article-title":"Primer3 on the WWW for general users and for biologist programmers","volume":"132","author":"Rozen","year":"2000","journal-title":"Methods Mol Biol"},{"key":"10.1002\/humu.21276-BIB24|cit24","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1073\/pnas.74.12.5463","article-title":"Dna sequencing with chain-terminating inhibitors","volume":"74","author":"Sanger","year":"1977","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.21276-BIB25|cit25","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nrg1607","article-title":"Genetics of Crohn disease, an archetypal inflammatory barrier disease","volume":"6","author":"Schreiber","year":"2005","journal-title":"Nat Rev Genet"},{"key":"10.1002\/humu.21276-BIB26|cit26","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/nmeth1156","article-title":"Next-generation sequencing transforms today's biology","volume":"5","author":"Schuster","year":"2008","journal-title":"Nat Methods"},{"key":"10.1002\/humu.21276-BIB27|cit27","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/nbt1486","article-title":"Next-generation DNA sequencing","volume":"26","author":"Shendure","year":"2008","journal-title":"Nat Biotechnol"},{"key":"10.1002\/humu.21276-BIB28|cit28","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1126\/science.1117389","article-title":"Accurate multiplex polony sequencing of an evolved bacterial genome","volume":"309","author":"Shendure","year":"2005","journal-title":"Science"},{"key":"10.1002\/humu.21276-BIB29|cit29","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/nar\/29.1.308","article-title":"dbSNP: the NCBI database of genetic variation","volume":"29","author":"Sherry","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"10.1002\/humu.21276-BIB30|cit30","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1101\/gr.077776.108","article-title":"Rapid whole-genome mutational profiling using next-generation sequencing technologies","volume":"18","author":"Smith","year":"2008","journal-title":"Genome Res"},{"key":"10.1002\/humu.21276-BIB31|cit31","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/319501","article-title":"A new statistical method for haplotype reconstruction from population data","volume":"68","author":"Stephens","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1002\/humu.21276-BIB32|cit32","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1101\/gr.091942.109","article-title":"Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing","volume":"19","author":"Summerer","year":"2009","journal-title":"Genome Res"},{"key":"10.1002\/humu.21276-BIB33|cit33","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/nature07484","article-title":"The diploid genome sequence of an Asian individual","volume":"456","author":"Wang","year":"2008","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB34|cit34","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1101\/gr.2754005","article-title":"novoSNP, a novel computational tool for sequence variation discovery","volume":"15","author":"Weckx","year":"2005","journal-title":"Genome Res"},{"key":"10.1002\/humu.21276-BIB35|cit35","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/nature06884","article-title":"The complete genome of an individual by massively parallel DNA sequencing","volume":"452","author":"Wheeler","year":"2008","journal-title":"Nature"},{"key":"10.1002\/humu.21276-BIB36|cit36","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00439-008-0535-3","article-title":"Comprehensive resequence analysis of a 136\u2009kb region of human chromosome 8q24 associated with prostate and colon cancers","volume":"124","author":"Yeager","year":"2008","journal-title":"Hum Genet"}],"container-title":["Human Mutation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhumu.21276","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/humu.21276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T16:54:00Z","timestamp":1672332840000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/humu.21276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,18]]},"references-count":36,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.1002\/humu.21276","relation":{},"ISSN":["1059-7794"],"issn-type":[{"value":"1059-7794","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5,18]]}}}