{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:19:41Z","timestamp":1779243581378,"version":"3.51.4"},"reference-count":49,"publisher":"Hindawi Limited","issue":"4","license":[{"start":{"date-parts":[[2012,2,14]],"date-time":"2012-02-14T00:00:00Z","timestamp":1329177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2012,2,14]],"date-time":"2012-02-14T00:00:00Z","timestamp":1329177600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Mutat."],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1002\/humu.22026","type":"journal-article","created":{"date-parts":[[2012,1,17]],"date-time":"2012-01-17T19:45:20Z","timestamp":1326829520000},"page":"703-709","source":"Crossref","is-referenced-by-count":13,"title":["Transcriptional hallmarks of noonan syndrome and noonan\u2010like syndrome with loose anagen hair"],"prefix":"10.1155","volume":"33","author":[{"given":"Giovanni Battista","family":"Ferrero","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Picco","sequence":"additional","affiliation":[{"name":"Department of Oncological Sciences, University of Torino Medical School, Torino, Italy"},{"name":"Laboratory of Oncogenomics, Institute for Cancer Research and Treatment, Candiolo (Torino), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppina","family":"Baldassarre","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Flex","sequence":"additional","affiliation":[{"name":"Dipartimento di Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanit\u00e0, Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Isella","sequence":"additional","affiliation":[{"name":"Department of Oncological Sciences, University of Torino Medical School, Torino, Italy"},{"name":"Laboratory of Oncogenomics, Institute for Cancer Research and Treatment, Candiolo (Torino), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Cantarella","sequence":"additional","affiliation":[{"name":"Department of Oncological Sciences, University of Torino Medical School, Torino, Italy"},{"name":"Laboratory of Oncogenomics, Institute for Cancer Research and Treatment, Candiolo (Torino), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Cor\u00e0","sequence":"additional","affiliation":[{"name":"Laboratory of Systems Biology, Institute for Cancer Research and Treatment (IRCC), 10060 Candiolo (Torino), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Chiesa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Crescenzio","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Timeus","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Merla","sequence":"additional","affiliation":[{"name":"Medical Genetics Unit, IRCCS \u2018Casa Sollievo della Sofferenza\u2019, S. Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Mazzanti","sequence":"additional","affiliation":[{"name":"Dipartimento di Pediatria, Universit\u00e0 degli Studi di Bologna, Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Zampino","sequence":"additional","affiliation":[{"name":"Istituto di Clinica Pediatrica, Universit\u00e0 Cattolica del Sacro Cuore, Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesare","family":"Rossi","sequence":"additional","affiliation":[{"name":"UO Genetica Medica, Policlinico S.Orsola\u2010Malpighi, Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margherita","family":"Silengo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Torino Medical School, Torino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Tartaglia","sequence":"additional","affiliation":[{"name":"Dipartimento di Ematologia, Oncologia e Medicina Molecolare, Istituto Superiore di Sanit\u00e0, Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enzo","family":"Medico","sequence":"additional","affiliation":[{"name":"Department of Oncological Sciences, University of Torino Medical School, Torino, Italy"},{"name":"Laboratory of Oncogenomics, Institute for Cancer Research and Treatment, Candiolo (Torino), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2012,2,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30138"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1987"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.08.005"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-08-2661"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-372"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2353\/jmoldx.2006.050079"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl483"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.425"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003405"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2007.10.002"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1128\/JVI.70.4.2260-2268.1996","article-title":"Raf\u20101 kinase targets GA\u2010binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter","volume":"70","author":"Flory E","year":"1996","journal-title":"J Virol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi002649m"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-3"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904336106"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.05238.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh218"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1093\/nar\/gki624","article-title":"oPOSSUM: identification of over\u2010represented transcription factor binding sites in co\u2010expressed genes","volume":"33","author":"Sui SJ","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"e_1_2_6_19_1","first-page":"1582","article-title":"GATA4 regulates ANF expression synergistically with Sp1 in a cardiac hypertrophy model","volume":"15","author":"Hu X","year":"2010","journal-title":"J Cell Mol Med"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.211"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.575"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-02-0531"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp026"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.369"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000218178"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2010.06.015"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.053975"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.10923"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.6.1823"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2004.08.011"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(03)00091-4"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.641"},{"key":"e_1_2_6_33_1","first-page":"67","article-title":"The two hats of SOS","volume":"189","author":"Nimnual A","year":"2002","journal-title":"Sci STKE"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208160"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2010.076836"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(98)70308-0"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2006.03.027"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703652104"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.02.016"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2109"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05790.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2010.09.002"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1086\/340847"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1939"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1159\/000276766"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2009.04.001"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-4"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320530213"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.2741\/3051"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(04)00050-4"}],"container-title":["Human Mutation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhumu.22026","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/humu.22026","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/humu.22026","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/humu.22026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T16:53:17Z","timestamp":1672332797000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/humu.22026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,14]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1002\/humu.22026"],"URL":"https:\/\/doi.org\/10.1002\/humu.22026","archive":["Portico"],"relation":{},"ISSN":["1059-7794","1098-1004"],"issn-type":[{"value":"1059-7794","type":"print"},{"value":"1098-1004","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,14]]}}}