{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:41:50Z","timestamp":1791092510720,"version":"4.1.0"},"reference-count":51,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":942,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Mutation"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1002\/humu.22276","type":"journal-article","created":{"date-parts":[[2013,1,18]],"date-time":"2013-01-18T15:09:26Z","timestamp":1358521766000},"page":"n\/a-n\/a","source":"Crossref","is-referenced-by-count":21,"title":["Genome-Wide Allelic Methylation Analysis Reveals Disease-Specific Susceptibility to Multiple Methylation Defects in Imprinting Syndromes"],"prefix":"10.1155","author":[{"given":"Franck","family":"Court","sequence":"first","affiliation":[{"name":"Imprinting and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet de Llobregat; Barcelona; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Martin-Trujillo","sequence":"additional","affiliation":[{"name":"Imprinting and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet de Llobregat; Barcelona; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Romanelli","sequence":"additional","affiliation":[{"name":"Imprinting and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet de Llobregat; Barcelona; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Intza","family":"Garin","sequence":"additional","affiliation":[{"name":"Molecular (Epi)Genetics Laboratory; Hospital Universitario Araba-Txagorritxu; Vitoria-Gasteiz; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Iglesias-Platas","sequence":"additional","affiliation":[{"name":"Neonatal Unit; Hospital Sant Joan de D\u00e9u; Barcelona; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Salafsky","sequence":"additional","affiliation":[{"name":"Division of Genetics, Evanston Hospital; Northwestern University Medical School; Evanston; Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Guitart","sequence":"additional","affiliation":[{"name":"Genetics Laboratory, UDIAT- Diagnostic Centre; Corporaci\u00f3 Sanit\u00e0ria Parc Taul\u00ed; Sabadell; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiomar","family":"Perez de Nanclares","sequence":"additional","affiliation":[{"name":"Molecular (Epi)Genetics Laboratory; Hospital Universitario Araba-Txagorritxu; Vitoria-Gasteiz; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Lapunzina","sequence":"additional","affiliation":[{"name":"Medical and Molecular Genetic Institute; University Hospital La Paz; Madrid; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Monk","sequence":"additional","affiliation":[{"name":"Imprinting and Cancer Group, Cancer Epigenetics and Biology Program (PEBC); Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet de Llobregat; Barcelona; Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2013,2,19]]},"reference":[{"key":"10.1002\/humu.22276-BIB0001|humu22276-cit-0001","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nmeth0410-248","article-title":"A method and server for predicting damaging missense mutations","volume":"7","author":"Adzhubei","year":"2010","journal-title":"Nat Methods"},{"key":"10.1002\/humu.22276-BIB0002|humu22276-cit-0002","doi-asserted-by":"crossref","first-page":"4724","DOI":"10.1093\/hmg\/ddp435","article-title":"Multilocus methylation analysis in a large cohort of 11p15-related foetal growth disorders (Russell Silver and Beckwith Wiedemann syndromes) reveals simultaneous loss of methylation at paternal and maternal imprinted loci","volume":"18","author":"Azzi","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1002\/humu.22276-BIB0003|humu22276-cit-0003","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1101\/gad.1841409","article-title":"Genomic imprinting: employing and avoiding epigenetic processes","volume":"15","author":"Bartolomei","year":"2009","journal-title":"Genes Dev"},{"key":"10.1002\/humu.22276-BIB0004|humu22276-cit-0004","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1399-0004.2010.01514.x","article-title":"Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues","volume":"80","author":"Begemann","year":"2011","journal-title":"Clin Genet"},{"key":"10.1002\/humu.22276-BIB0005|humu22276-cit-0005","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/ejhg.2008.233","article-title":"Hypomethylation at multiple maternally methylated imprinted regions including PLAGL1 and GNAS loci in Beckwith-Wiedemann syndrome","volume":"17","author":"Bliek","year":"2009a","journal-title":"Eur J Hum Genet"},{"key":"10.1002\/humu.22276-BIB0006|humu22276-cit-0006","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1038\/ejhg.2009.77","article-title":"Lessons from BWS twins: complex maternal and paternal hypomethylation and a common source of haematopoietic stem cells","volume":"17","author":"Bliek","year":"2009b","journal-title":"Eur J Hum Genet"},{"key":"10.1002\/humu.22276-BIB0007|humu22276-cit-0007","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/sj.ejhg.5201993","article-title":"Clinical characterisation of the multiple maternal hypomethylation syndrome in siblings","volume":"16","author":"Boonen","year":"2008","journal-title":"Eur J Hum Genet"},{"key":"10.1002\/humu.22276-BIB0008|humu22276-cit-0008","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/ejhg.2011.140","article-title":"No evidence for pathogenic variants or maternal effect of ZFP57 as the cause of Beckwith-Wiedemann Syndrome","volume":"20","author":"Boonen","year":"2012","journal-title":"Eur J Hum Genet"},{"key":"10.1002\/humu.22276-BIB0009|humu22276-cit-0009","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/ajmg.c.30273","article-title":"Prader-Willi syndrome and Angelman syndrome","volume":"154C","author":"Buiting","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/humu.22276-BIB0010|humu22276-cit-0010","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/B978-0-12-380916-2.00005-X","article-title":"RB1, development and cancer","volume":"94","author":"Chinnam","year":"2011","journal-title":"Curr Top Dev Biol"},{"key":"10.1002\/humu.22276-BIB0011|humu22276-cit-0011","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/ijc.24384","article-title":"Changes in DNA methylation of tandem DNA repeats are different from interspersed repeats in cancer","volume":"125","author":"Choi","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1002\/humu.22276-BIB0012|humu22276-cit-0012","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/ajmg.c.30267","article-title":"Beckwith-Wiedemann syndrome","volume":"154C","author":"Choufani","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/humu.22276-BIB0013|humu22276-cit-0013","doi-asserted-by":"crossref","first-page":"5475","DOI":"10.1128\/MCB.23.16.5475-5488.2003","article-title":"Epigenetic properties and identification of an imprint mark in the Nesp-Gnasxl domain of the mouse Gnas imprinted locus","volume":"23","author":"Coombes","year":"2003","journal-title":"Mol Cell Biol"},{"key":"10.1002\/humu.22276-BIB0014|humu22276-cit-0014","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1002\/bies.201100060","article-title":"Is there a genomically imprinted social brain","volume":"33","author":"Curley","year":"2011","journal-title":"Bioassays"},{"key":"10.1002\/humu.22276-BIB0015|humu22276-cit-0015","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/hmg\/ddp549","article-title":"Analysis of the IGF2\/H19 imprinting control region uncovers new genetic defects, including mutations of OCT-binding sequences, in patients with 11p15 fetal growth disorders","volume":"19","author":"Demars","year":"2010","journal-title":"Hum Mol Genet"},{"key":"10.1002\/humu.22276-BIB0016|humu22276-cit-0016","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/ajmg.c.30274","article-title":"Russell-Silver syndrome","volume":"154C","author":"Eggermann","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/humu.22276-BIB0017|humu22276-cit-0017","doi-asserted-by":"crossref","first-page":"E629","DOI":"10.1002\/humu.20993","article-title":"Genetic and epigenetic analysis of recurrent hydatidiform mole","volume":"30","author":"Hayward","year":"2009","journal-title":"Hum Mutat"},{"key":"10.1002\/humu.22276-BIB0018|humu22276-cit-0018","doi-asserted-by":"crossref","first-page":"e38907","DOI":"10.1371\/journal.pone.0038907","article-title":"Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin","volume":"7","author":"Iglesias-Platas","year":"2012","journal-title":"PLoS One"},{"key":"10.1002\/humu.22276-BIB0019|humu22276-cit-0019","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/ng.2007.56","article-title":"Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes","volume":"40","author":"Kagami","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/humu.22276-BIB0020|humu22276-cit-0020","doi-asserted-by":"crossref","first-page":"e1000992","DOI":"10.1371\/journal.pgen.1000992","article-title":"The IG-DMR and the MEG3-DMR at human chromosome 14q32.2: hierarchical interaction and distinct functional properties as imprinting control centers","volume":"6","author":"Kagami","year":"2010","journal-title":"PLoS Genet"},{"key":"10.1002\/humu.22276-BIB0021|humu22276-cit-0021","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/ajmg.c.30271","article-title":"Imprinting on chromosome 20: tissue-specific imprinting and imprinting mutations in the GNAS locus","volume":"154C","author":"Kelsey","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/humu.22276-BIB0022|humu22276-cit-0022","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.devcel.2008.08.014","article-title":"A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints","volume":"15","author":"Li","year":"2008","journal-title":"Dev Cell"},{"key":"10.1002\/humu.22276-BIB0023|humu22276-cit-0023","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/humrep\/den406","article-title":"Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies","volume":"24","author":"Lim","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1002\/humu.22276-BIB0024|humu22276-cit-0024","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/hmg\/ddg022","article-title":"Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions","volume":"12","author":"Lopes","year":"2003","journal-title":"Hum Mol Genet"},{"key":"10.1002\/humu.22276-BIB0025|humu22276-cit-0025","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s00439-006-0205-2","article-title":"A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus","volume":"120","author":"Mackay","year":"2006","journal-title":"Hum Genet"},{"key":"10.1002\/humu.22276-BIB0026|humu22276-cit-0026","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/ng.187","article-title":"Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57","volume":"40","author":"Mackay","year":"2008","journal-title":"Nat Genet"},{"key":"10.1002\/humu.22276-BIB0027|humu22276-cit-0027","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/ajmg.c.30272","article-title":"Transient neonatal diabetes mellitus type 1","volume":"154C","author":"Mackay","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/humu.22276-BIB0028|humu22276-cit-0028","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1126\/science.1216154","article-title":"Trim28 is required for epigenetic stability during mouse oocyte to embryo transition","volume":"335","author":"Messerschmidt","year":"2012","journal-title":"Science"},{"key":"10.1002\/humu.22276-BIB0029|humu22276-cit-0029","doi-asserted-by":"crossref","first-page":"e1000423","DOI":"10.1371\/journal.pgen.1000423","article-title":"Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome)","volume":"5","author":"Meyer","year":"2009","journal-title":"PLoS Genet"},{"key":"10.1002\/humu.22276-BIB0030|humu22276-cit-0030","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/ng1740","article-title":"Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans","volume":"38","author":"Murdoch","year":"2006","journal-title":"Nat Genet"},{"key":"10.1002\/humu.22276-BIB0031|humu22276-cit-0031","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1093\/hmg\/ddr224","article-title":"Methylation screening of reciprocal genome-wide UPDs identifies novel human-specific imprinted genes","volume":"20","author":"Nakabayashi","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1002\/humu.22276-BIB0032|humu22276-cit-0032","doi-asserted-by":"crossref","first-page":"e89","DOI":"10.1371\/journal.pgen.0030089","article-title":"Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs","volume":"3","author":"O'Geen","year":"2007","journal-title":"PLoS Genet"},{"key":"10.1002\/humu.22276-BIB0033|humu22276-cit-0033","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.ajhg.2011.08.002","article-title":"Mutations causing familial biparental hydatidiform mole implicate C6ORF221 as a possible regulator of genomic imprinting in the human oocyte","volume":"89","author":"Parry","year":"2011","journal-title":"Am J Hum Genet"},{"key":"10.1002\/humu.22276-BIB0034|humu22276-cit-0034","doi-asserted-by":"crossref","first-page":"E1060","DOI":"10.1210\/jc.2012-1081","article-title":"Detection of hypomethylation syndrome among patients with epigenetic alterations at the GNAS locus","volume":"97","author":"Perez-Nanclares","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/humu.22276-BIB0035|humu22276-cit-0035","doi-asserted-by":"crossref","first-page":"652","DOI":"10.4161\/epi.20221","article-title":"Different measures of \u201cgenome-wide\u201d DNA methylation exhibit unique properties in placental and somatic tissues","volume":"7","author":"Price","year":"2012","journal-title":"Epigenetics"},{"key":"10.1002\/humu.22276-BIB0036|humu22276-cit-0036","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/humu.9498","article-title":"Women heterozygous for NALP7\/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations","volume":"28","author":"Qian","year":"2007","journal-title":"Hum Mutat"},{"key":"10.1002\/humu.22276-BIB0037|humu22276-cit-0037","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.molcel.2011.08.032","article-title":"In embryonic stem cells, ZFP57\/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions","volume":"44","author":"Quenneville","year":"2011","journal-title":"Mol Cell"},{"key":"10.1002\/humu.22276-BIB0038|humu22276-cit-0038","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1136\/jmg.2006.042135","article-title":"The epigenetic imprinting defect of patients with Beckwith-Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region","volume":"43","author":"Rossignol","year":"2006","journal-title":"J Med Genet"},{"key":"10.1002\/humu.22276-BIB0039|humu22276-cit-0039","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/ng.864","article-title":"Dynamic CpG island methylation landscape in oocytes and preimplantation embryos","volume":"43","author":"Smallwood","year":"2011","journal-title":"Nat Genet"},{"key":"10.1002\/humu.22276-BIB0040|humu22276-cit-0040","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.ejmg.2009.07.005","article-title":"Screening for genomic variants in ZFP57 in Silver-Russell syndrome patients with 11p15 epimutations","volume":"52","author":"Spengler","year":"2009","journal-title":"Eur J Med Genet"},{"key":"10.1002\/humu.22276-BIB0041|humu22276-cit-0041","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1242\/dev.061416","article-title":"Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes","volume":"138","author":"Tomizawa","year":"2011","journal-title":"Development"},{"key":"10.1002\/humu.22276-BIB0042|humu22276-cit-0042","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/gb-2003-4-10-231","article-title":"KRAB-containing zinc-finger repressor proteins","volume":"4","author":"Urrutia","year":"2003","journal-title":"Genome Biol"},{"key":"10.1002\/humu.22276-BIB0043|humu22276-cit-0043","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/humupd\/dmk005","article-title":"Biparental hydatidiform moles: a maternal effect mutation affecting imprinting in the offspring","volume":"12","author":"Van den Veyver","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1002\/humu.22276-BIB0044|humu22276-cit-0044","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/jmg.2008.064196","article-title":"Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region","volume":"46","author":"Wang","year":"2009","journal-title":"J Med Genet"},{"key":"10.1002\/humu.22276-BIB0045|humu22276-cit-0045","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1093\/hmg\/11.11.1317","article-title":"Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome","volume":"11","author":"Weksberg","year":"2002","journal-title":"Hum Mol Genet."},{"key":"10.1002\/humu.22276-BIB0046|humu22276-cit-0046","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/ng1731","article-title":"Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster","volume":"38","author":"Williamson","year":"2006","journal-title":"Nat Genet"},{"key":"10.1002\/humu.22276-BIB0047|humu22276-cit-0047","doi-asserted-by":"crossref","first-page":"2859","DOI":"10.1101\/gad.1452206","article-title":"Deficiency of Rbbp1\/Arid4a and Rbbp1l1\/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS\/AS domain","volume":"20","author":"Wu","year":"2006","journal-title":"Genes Dev"},{"key":"10.1002\/humu.22276-BIB0048|humu22276-cit-0048","doi-asserted-by":"crossref","first-page":"12417","DOI":"10.1073\/pnas.0801540105","article-title":"The H19 locus acts in vivo as a tumor suppressor","volume":"105","author":"Yoshimizu","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.22276-BIB0049|humu22276-cit-0049","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1073\/pnas.96.1.214","article-title":"NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas","volume":"96","author":"Yu","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/humu.22276-BIB0050|humu22276-cit-0050","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1399-0004.2008.01116.x","article-title":"Epimutation at human chromosome 14q32.2 in a boy with a upd(14)mat-like clinical phenotype","volume":"75","author":"Zechner","year":"2009","journal-title":"Clin Genet"},{"key":"10.1002\/humu.22276-BIB0051|humu22276-cit-0051","doi-asserted-by":"crossref","first-page":"e2755","DOI":"10.1371\/journal.pone.0002755","article-title":"Expression analysis of the NLRP gene family suggests a role in human preimplantation development","volume":"3","author":"Zhang","year":"2008","journal-title":"PLoS One"}],"container-title":["Human Mutation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhumu.22276","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/humu.22276\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T16:54:48Z","timestamp":1672332888000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/humu.22276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":51,"URL":"https:\/\/doi.org\/10.1002\/humu.22276","relation":{},"ISSN":["1059-7794"],"issn-type":[{"value":"1059-7794","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}