{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T12:01:01Z","timestamp":1774958461930,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"4-5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1553,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hum. Psychopharmacol Clin Exp"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1002\/hup.1210","type":"journal-article","created":{"date-parts":[[2011,6,22]],"date-time":"2011-06-22T07:52:10Z","timestamp":1308729130000},"page":"332-337","source":"Crossref","is-referenced-by-count":10,"title":["Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain"],"prefix":"10.1002","volume":"26","author":[{"given":"Young-Min","family":"Park","sequence":"first","affiliation":[{"name":"Department of Psychiatry; Inje University College of Medicine; Goyang; South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Eun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Gul","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry; Catholic University of Daegu School of Medicine; Daegu; South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Hoi","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Molecular Cellular Biology; Sungkyunkwan University School of Medicine; Suwon; Gyeonggi-do; South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leen","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Psychiatry; Korea University College of Medicine; Seoul; South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongho","family":"Geum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heon-Jeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,6,22]]},"reference":[{"key":"10.1002\/hup.1210-BIB1210-bib-0001|hup1210-cit-0001","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1176\/appi.ps.54.4.565","article-title":"The impact of weight gain on quality of life among persons with schizophrenia","volume":"54","author":"Allison","year":"2003","journal-title":"Psychiatr Serv"},{"key":"10.1002\/hup.1210-BIB1210-bib-0002|hup1210-cit-0002","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1176\/ajp.156.11.1686","article-title":"Antipsychotic-induced weight gain: a comprehensive research synthesis","volume":"156","author":"Allison","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1002\/hup.1210-BIB1210-bib-0003|hup1210-cit-0003","volume-title":"Diagnostic and statistical manual of mental disorders: DSM-IV","author":"American Psychiatric Association","year":"1994"},{"key":"10.1002\/hup.1210-BIB1210-bib-0004|hup1210-cit-0004","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1600-0447.1999.tb10908.x","article-title":"Body weight gain induced by antipsychotic drugs: mechanisms and management","volume":"100","author":"Baptista","year":"1999","journal-title":"Acta Psychiatr Scand"},{"key":"10.1002\/hup.1210-BIB1210-bib-0005|hup1210-cit-0005","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.coph.2006.09.001","article-title":"Cannabinoid receptors as therapeutic targets for obesity and metabolic diseases","volume":"6","author":"Bellocchio","year":"2006","journal-title":"Curr Opin Pharmacol"},{"key":"10.1002\/hup.1210-BIB1210-bib-0006|hup1210-cit-0006","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1093\/hmg\/ddn089","article-title":"Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations","volume":"17","author":"Benzinou","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1002\/hup.1210-BIB1210-bib-0007|hup1210-cit-0007","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1079\/BJN20041256","article-title":"Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide","volume":"92","author":"Cani","year":"2004","journal-title":"Br J Nutr"},{"key":"10.1002\/hup.1210-BIB1210-bib-0008|hup1210-cit-0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/geno.1997.4815","article-title":"Suggestive evidence for a schizophrenia susceptibility locus on chromosome 6q and a confirmation in an independent series of pedigrees","volume":"43","author":"Cao","year":"1997","journal-title":"Genomics"},{"issue":"Suppl 7","key":"10.1002\/hup.1210-BIB1210-bib-0009|hup1210-cit-0009","first-page":"4","article-title":"The pharmacology of weight gain with antipsychotics","volume":"62","author":"Casey","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"10.1002\/hup.1210-BIB1210-bib-0010|hup1210-cit-0010","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/35071088","article-title":"Leptin-regulated endocannabinoids are involved in maintaining food intake","volume":"410","author":"Marzo","year":"2001","journal-title":"Nature"},{"key":"10.1002\/hup.1210-BIB1210-bib-0011|hup1210-cit-0011","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.tcm.2006.11.003","article-title":"Endocannabinoid antagonism: blocking the excess in the treatment of high-risk abdominal obesity","volume":"17","author":"Duffy","year":"2007","journal-title":"Trends Cardiovasc Med"},{"key":"10.1002\/hup.1210-BIB1210-bib-0012|hup1210-cit-0012","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1006\/mcpr.1999.0249","article-title":"A frequent polymorphism in the coding exon of the human cannabinoid receptor (CNR1) gene","volume":"13","author":"Gadzicki","year":"1999","journal-title":"Mol Cell Probes"},{"key":"10.1002\/hup.1210-BIB1210-bib-0013|hup1210-cit-0013","volume-title":"Structured Clinical Interview for DSM-IV Axis I Disorder-Korean Version","author":"Han","year":"2000"},{"key":"10.1002\/hup.1210-BIB1210-bib-0014|hup1210-cit-0014","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1124\/pr.54.2.161","article-title":"International Union of Pharmacology. XXVII. Classification of cannabinoid receptors","volume":"54","author":"Howlett","year":"2002","journal-title":"Pharmacol Rev"},{"key":"10.1002\/hup.1210-BIB1210-bib-0015|hup1210-cit-0015","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0022-3956(98)00023-5","article-title":"New atypical antipsychotic medications","volume":"32","author":"Jibson","year":"1998","journal-title":"J Psychiatr Res"},{"key":"10.1002\/hup.1210-BIB1210-bib-0016|hup1210-cit-0016","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.pnpbp.2007.08.002","article-title":"Possible association between the -2548A\/G polymorphism of the leptin gene and olanzapine-induced weight gain","volume":"32","author":"Kang","year":"2008","journal-title":"Prog Neuro Psychopharmacol Biol Psychiatry"},{"key":"10.1002\/hup.1210-BIB1210-bib-0017|hup1210-cit-0017","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/JCP.0b013e3181e742c5","article-title":"Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359\u2009G\/A CNR1 polymorphism is associated with antipsychotic-induced weight gain","volume":"30","author":"Monteleone","year":"2010","journal-title":"J Clin Psychopharmacol"},{"key":"10.1002\/hup.1210-BIB1210-bib-0018|hup1210-cit-0018","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ymgme.2007.01.002","article-title":"No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents","volume":"90","author":"Muller","year":"2007","journal-title":"Mol Genet Metab"},{"issue":"Suppl 1","key":"10.1002\/hup.1210-BIB1210-bib-0019|hup1210-cit-0019","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0306-4530(02)00114-2","article-title":"A review of the effect of atypical antipsychotics on weight","volume":"28","author":"Nasrallah","year":"2003","journal-title":"Psychoneuroendocrinology"},{"key":"10.1002\/hup.1210-BIB1210-bib-0020|hup1210-cit-0020","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.jada.2005.04.005","article-title":"Dietary influences on peripheral hormones regulating energy intake: potential applications for weight management","volume":"105","author":"Orr","year":"2005","journal-title":"J Am Diet Assoc"},{"issue":"Suppl 1","key":"10.1002\/hup.1210-BIB1210-bib-0021|hup1210-cit-0021","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1038\/sj.ijo.0803276","article-title":"The role of the endocannabinoid system in the control of energy homeostasis","volume":"30","author":"Osei-Hyiaman","year":"2006","journal-title":"Int J Obes (2005)"},{"key":"10.1002\/hup.1210-BIB1210-bib-0022|hup1210-cit-0022","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1210\/er.2005-0009","article-title":"The emerging role of the endocannabinoid system in endocrine regulation and energy balance","volume":"27","author":"Pagotto","year":"2006","journal-title":"Endocr Rev"},{"key":"10.1002\/hup.1210-BIB1210-bib-0023|hup1210-cit-0023","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2710.2008.00872.x","article-title":"Lack of association between the -759\u2009C\/T polymorphism of the 5-HT2C receptor gene and olanzapine-induced weight gain among Korean schizophrenic patients","volume":"33","author":"Park","year":"2008","journal-title":"J Clin Pharm Ther"},{"key":"10.1002\/hup.1210-BIB1210-bib-0024|hup1210-cit-0024","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/ajmg.b.30311","article-title":"Weight gain associated with the alpha2a-adrenergic receptor\u22121291 C\/G polymorphism and olanzapine treatment","volume":"141B","author":"Park","year":"2006","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1002\/hup.1210-BIB1210-bib-0025|hup1210-cit-0025","doi-asserted-by":"crossref","first-page":"39","DOI":"10.4306\/pi.2009.6.1.39","article-title":"G-protein beta3 subunit gene 825 C\/T polymorphism is not associated with olanzapine-induced weight gain in Korean schizophrenic patients","volume":"6","author":"Park","year":"2009","journal-title":"Psychiatry Investig"},{"key":"10.1002\/hup.1210-BIB1210-bib-0026|hup1210-cit-0026","doi-asserted-by":"crossref","first-page":"147","DOI":"10.4306\/pi.2010.7.2.147","article-title":"Lack of association between glutathione s-transferase-M1, -T1, and -P1 polymorphisms and olanzapine-induced weight gain in Korean schizophrenic patients","volume":"7","author":"Park","year":"2010","journal-title":"Psychiatry Investig"},{"issue":"Suppl 21","key":"10.1002\/hup.1210-BIB1210-bib-0027|hup1210-cit-0027","first-page":"25","article-title":"Adherence to antipsychotic medications","volume":"60","author":"Perkins","year":"1999","journal-title":"J Clin Psychiatry"},{"key":"10.1002\/hup.1210-BIB1210-bib-0028|hup1210-cit-0028","first-page":"R345","article-title":"Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice","volume":"284","author":"Ravinet Trillou","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1002\/hup.1210-BIB1210-bib-0029|hup1210-cit-0029","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/sj.ijo.0802583","article-title":"CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity","volume":"28","author":"Ravinet Trillou","year":"2004","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1002\/hup.1210-BIB1210-bib-0030|hup1210-cit-0030","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1210\/jc.2006-2523","article-title":"Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men","volume":"92","author":"Russo","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1002\/hup.1210-BIB1210-bib-0031|hup1210-cit-0031","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0920-9964(02)00441-3","article-title":"Body mass index and quality of life in community-dwelling patients with schizophrenia","volume":"62","author":"Strassnig","year":"2003","journal-title":"Schizophr Res"},{"key":"10.1002\/hup.1210-BIB1210-bib-0032|hup1210-cit-0032","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1034\/j.1600-0447.2000.101006416.x","article-title":"Atypical antipsychotics and weight gain--a systematic review","volume":"101","author":"Taylor","year":"2000","journal-title":"Acta Psychiatr Scand"},{"key":"10.1002\/hup.1210-BIB1210-bib-0033|hup1210-cit-0033","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/sj.tpj.6500418","article-title":"No evidence for binding of clozapine, olanzapine and\/or haloperidol to selected receptors involved in body weight regulation","volume":"7","author":"Theisen","year":"2007","journal-title":"Pharmacogenomics J"},{"key":"10.1002\/hup.1210-BIB1210-bib-0034|hup1210-cit-0034","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1038\/npp.2009.235","article-title":"A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia","volume":"35","author":"Tiwari","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1002\/hup.1210-BIB1210-bib-0035|hup1210-cit-0035","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.psychres.2003.07.004","article-title":"Understanding adherence to neuroleptic treatment in schizophreniai","volume":"126","author":"Vauth","year":"2004","journal-title":"Psychiatry Res"},{"key":"10.1002\/hup.1210-BIB1210-bib-0036|hup1210-cit-0036","first-page":"827","article-title":"The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: implications for olanzapine-induced weight gain","volume":"11","author":"Weston-Green","year":"2008","journal-title":"Int J Neuropsychopharmacol Off Sci J Coll Int Neuropsychopharmacologicum CINP"},{"key":"10.1002\/hup.1210-BIB1210-bib-0037|hup1210-cit-0037","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.neuropharm.2008.07.026","article-title":"Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats","volume":"55","author":"Wiley","year":"2008","journal-title":"Neuropharmacology"}],"container-title":["Human Psychopharmacology: Clinical and Experimental"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhup.1210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/hup.1210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T15:31:41Z","timestamp":1686151901000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hup.1210"}},"subtitle":["OLANZAPINE-INDUCED WEIGHT GAIN AND CNR1"],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":37,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2011,6]]}},"URL":"https:\/\/doi.org\/10.1002\/hup.1210","relation":{},"ISSN":["0885-6222"],"issn-type":[{"value":"0885-6222","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}