{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:15:59Z","timestamp":1758478559156},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T00:00:00Z","timestamp":1353456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Antipsychotic\u2010induced weight gain is a problematic side effect. The mechanism is still not fully understood. Carbohydrate (and possibly other food) cravings have been suggested in literature, but not been systematically investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the hypothesis that food cravings, especially for carbohydrate, are responsible for olanzapine\u2010induced weight gain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A case control design was used to measure general and specific food cravings using Food Craving Inventory (White <jats:italic>et al<\/jats:italic>., 2002) in three groups: patients with a diagnosis of schizophrenia taking olanzapine (Number\u2009=\u200920) or typical antipsychotics (Number\u2009=\u200920) and in a healthy control group (Number\u2009=\u200920).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No statistically significant differences were found between the three groups in the craving scores. There was a trend in the typical group to show more cravings than other groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study failed to prove the hypothesis that carbohydrate craving is responsible for olanzapine\u2010induced weight gain. This conclusion is limited by the small number of the subjects included. 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