{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T16:10:38Z","timestamp":1700410238219},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,3,29]],"date-time":"2001-03-29T00:00:00Z","timestamp":985824000000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2001,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study attempted to replicate previous reports of associations between panic disorder and joint hyperlaxity. The authors also examined possible associations between reacitivity to carbon dioxide (CO<jats:sub>2<\/jats:sub>), a model for panic vulnerability, and hyperlaxity in healthy volunteers. One hundred and one patients with DSM\u2010IV panic disorder and 39 healthy volunteers were assessed for hyperlaxity by Beighton's criteria. Healthy volunteers also received two vital capacity inhalations of CO<jats:sub>2<\/jats:sub>. Thirteen (13%) patients had five or more hyperlax joints. This rate did not differ from that in the healthy volunteers. Anxiety in healthy volunteers, as measured by the NIMH self\u2010rating scale, DSM\u2010IV panic symptom scores, and 100\u2009mm visual analog scales of anxiety, increased after CO<jats:sub>2<\/jats:sub> from a mean of 1.8 to 2.8 (not significant); from 0.5 to 4 (\u2009<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and from 8.7 to 11.6\u2009mm (\u2009<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.1), respectively. There were no associations between responses to CO<jats:sub>2<\/jats:sub> and hyperlaxity. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hup.234","type":"journal-article","created":{"date-parts":[[2005,1,25]],"date-time":"2005-01-25T01:31:55Z","timestamp":1106616715000},"page":"189-192","source":"Crossref","is-referenced-by-count":6,"title":["Lack of association between joint hyperlaxity and, I: panic disorder, and II: reactivity to carbon dioxide in healthy volunteers"],"prefix":"10.1002","volume":"16","author":[{"given":"Jonathan","family":"Benjamin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itzhak Z","family":"Ben\u2010Zion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinhas","family":"Dannon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaul","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gal","family":"Meiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Ofek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Palatnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,3,29]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4471-3900-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.32.5.413"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02805987"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(93)90008-5"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)90514-4"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.52.7.494"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.155.11.1578"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00444705"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.152.4.623"},{"key":"e_1_2_1_11_1","volume-title":"Structured Clinical Interview for DSM\u2010III\u2010R (SCID, version 1.0)","author":"Spitzer R","year":"1990"}],"container-title":["Human Psychopharmacology: Clinical and Experimental"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhup.234","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hup.234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T15:34:21Z","timestamp":1700408061000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hup.234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,3]]}},"alternative-id":["10.1002\/hup.234"],"URL":"https:\/\/doi.org\/10.1002\/hup.234","archive":["Portico"],"relation":{},"ISSN":["0885-6222","1099-1077"],"issn-type":[{"value":"0885-6222","type":"print"},{"value":"1099-1077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,3]]}}}