{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T20:03:56Z","timestamp":1760385836007,"version":"3.41.2"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:00:00Z","timestamp":1618358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Inpatients with coronavirus disease 2019 (COVID\u201019) show a high rate of neuropsychiatric manifestations, possibly related to a higher risk of serious illness or death. Use of psychotropic medications (PMs) indicates the presence of neuropsychiatric symptoms in COVID\u201019 patients. So far, potential clinical predictors of use of PMs have not been much investigated. In order to extend research in this area, we aimed to investigate the prevalence of PM prescription among a sample of inpatients with COVID\u201019 and to find potential predictors of initiation of PMs in these individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a cross\u2010sectional single\u2010center study, conducted during the first outbreak peak in a hospital of northern Italy. Information on socio\u2010demographic characteristics, comorbidities, routine blood test, use of potential COVID\u201019 treatments, and length of stay were retrieved from medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data were available for 151 inpatients. Forty\u2010seven of them (31.1%) started at least one prescription of a PM. PM prescription was significantly inversely associated with lymphocyte and platelet counts. A significant association was also found for lactate dehydrogenase (LDH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings suggest that the initiation of PMs could be common among COVID\u201019 inpatients. Lymphocyte and platelet counts as well as LDH levels may reflect neuropsychiatric complications of COVID\u201019.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hup.2789","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T03:44:25Z","timestamp":1618458265000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Initiation of psychotropic medication in hospitalized patients with COVID\u201019: Association with clinical and biological characteristics"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8350-499X","authenticated-orcid":false,"given":"Enrico","family":"Capuzzi","sequence":"first","affiliation":[{"name":"Psychiatric Department Azienda Socio Sanitaria Territoriale Monza  Monza Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Caldiroli","sequence":"additional","affiliation":[{"name":"Psychiatric Department 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