{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:33:13Z","timestamp":1783427593896,"version":"3.54.6"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare opioid use disorder (OUD) patients who continue to use opioids and are in remission with buprenorphine\u2010naloxone (B\/N) in terms of some parameters and to evaluate the relationship between B\/N dose and these parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We included 141 OUD patients in remission with B\/N maintenance treatment for at least 6\u00a0months, 141 who still used opioids, and 141 healthy volunteers. Substance Craving Scale (SCS), Pittsburgh Sleep Quality Index (PSQI), Arizona Sexual Experiences Scale (ASEX), and Short Form 36 (SF\u201036) were administered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>PSQI scores and ASEX scores were higher in those who continued to use opiates than in OUD in remission, and in OUD in remission compared to controls. OUD patients with current opioid use also had lower SF\u201036 scores compared to both patients in remission and healthy controls. SCS, PSQI, ASEX, and SF\u201036 scores were similar when the three groups were examined based on the dosage of B\/N (below 8, 8\u201315, and 16\u00a0mg\/day and above) use in OUD in remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Quality of life, craving, sleep and sexual functions improved significantly with B\/N; however, these effects are not dependent on B\/N dosage.<\/jats:p><\/jats:sec>","DOI":"10.1002\/hup.2908","type":"journal-article","created":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T14:22:05Z","timestamp":1720966925000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative evaluation of craving, sleep quality, sexual function and quality of life in opioid use disorder patients in remission with buprenorphine\/naloxone maintenance treatment"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3345-2085","authenticated-orcid":false,"given":"Z\u00fcbeyde G\u00fcll\u00fc","family":"T\u00fcrker","sequence":"first","affiliation":[{"name":"Department of Psychiatry Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0329-6778","authenticated-orcid":false,"given":"Ali","family":"Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6480-1454","authenticated-orcid":false,"given":"Buket","family":"Cinemre","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7679-6357","authenticated-orcid":false,"given":"\u00d6zmen","family":"Metin","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6566-5850","authenticated-orcid":false,"given":"Burak","family":"Kulaks\u0131zo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ADT.0b013e31802b4e8c"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.5505\/kpd.2022.65148"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2022.107589"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.12.153"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S276708"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.5152\/ADDICTA.2022.22036"},{"issue":"1","key":"e_1_2_11_8_1","first-page":"35","article-title":"Opioid substitution with methadone and buprenorphine: Sexual dysfunction as a side effect of therapy","volume":"9","author":"Brown R. T.","year":"2007","journal-title":"Heroin Addiction and Related Clinical Problems"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165\u20101781(89)90047\u20104"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP14339.RA"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2017.07.016"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pbr.2015.10.002"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hup.2730"},{"issue":"1","key":"e_1_2_11_14_1","first-page":"70","article-title":"Reliability and validity of the Penn alcohol craving scale (PACS) revised version for substance craving in male substance dependent inpatients","volume":"22","author":"Evren C.","year":"2011","journal-title":"T\u00fcrk Psikiyatri Dergisi"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2010.505991"},{"key":"e_1_2_11_16_1","first-page":"1","volume-title":"Structured clinical interview for the DSM (SCID)","author":"First M. B.","year":"2014"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976\u20103147.139986"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2022.109445"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2014.07.035"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010001\u20100975\u20100"},{"key":"e_1_2_11_22_1","volume-title":"Clinical methods: The history, physical, and laboratory examinations","author":"Griffin J. B.","year":"1990"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2011.596974"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/03639045.2019.1706552"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2019.00592"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2007.10.017"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.4103\/psychiatry.IndianJPsychiatry_195_19"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/009262300278623"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2015.1014948"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2019.06.012"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3109\/00952990.2013.848875"},{"key":"e_1_2_11_32_1","unstructured":"World Drug Report.2023.https:\/\/www.unodc.org\/unodc\/en\/data\u2010and\u2010analysis\/world\u2010drug\u2010report\u20102023.html"},{"issue":"1","key":"e_1_2_11_33_1","article-title":"Self\u2010reported sleep improvement in buprenorphine MAT (medication assisted treatment) population","volume":"3","author":"Zheng W. H.","year":"2016","journal-title":"Austin Journal of Drug Abuse and Addiction"}],"container-title":["Human Psychopharmacology: Clinical and Experimental"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/hup.2908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T11:44:49Z","timestamp":1747395889000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/hup.2908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,14]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/hup.2908"],"URL":"https:\/\/doi.org\/10.1002\/hup.2908","archive":["Portico"],"relation":{},"ISSN":["0885-6222","1099-1077"],"issn-type":[{"value":"0885-6222","type":"print"},{"value":"1099-1077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,14]]},"assertion":[{"value":"2024-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2908"}}