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In a double\u2010blind study we examined its effects in 30 healthy, non sleep\u2010deprived students (19 men and 11 women, aged 19\u201323 years), who were randomly allocated to placebo, 100 or 200\u2009mg modafinil and 3\u2009h later completed 100\u2009mm visual analogue scales relating to mood and bodily symptoms, before and after an extensive battery of cognitive tests (pen and paper and CANTAB). There were no significant differences between the three treatment groups on any of the cognitive tests used in this study. There was a significant post\u2010treatment change in the factor measuring \u2018somatic anxiety\u2019 and in individual ratings of \u2018shaking\u2019, \u2018palpitations\u2019, \u2018dizziness\u2019, \u2018restlessness\u2019, \u2018muscular tension\u2019, \u2018physical tiredness\u2019 and \u2018irritability\u2019, which was mainly due to significantly higher ratings of somatic anxiety in the 100\u2009mg group compared with the other two groups. Further changes in mood were revealed after the stress of cognitive testing, with the 100\u2009mg group showing greater increases in the \u2018psychological anxiety\u2019 and the \u2018aggressive mood\u2019 factors (as measured from the Bond and Lader scales). Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hup.456","type":"journal-article","created":{"date-parts":[[2003,3,28]],"date-time":"2003-03-28T12:22:50Z","timestamp":1048854170000},"page":"163-173","source":"Crossref","is-referenced-by-count":89,"title":["Modafinil affects mood, but not cognitive function, in healthy young volunteers"],"prefix":"10.1002","volume":"18","author":[{"given":"Delia C.","family":"Randall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Shneerson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komal K.","family":"Plaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra 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