{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:22:05Z","timestamp":1792264925761,"version":"4.4.0"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study examined the reported psychological effects of different patterns of MDMA use in men and women, and how they are modified by use of other psychoactive substances. A semi\u2010structured interview was conducted with 466 regular MDMA users, exploring the perceived acute, sub\u2010acute and long\u2010term subjective effects of this drug. Factor analysis established three main categories of acute effects of MDMA: (i) positive and (ii) negative effects on mental health, and (iii) physical effects. In terms of subacute effects, 83% of participants reported experiencing low mood and 80% reported impaired concentration between ecstasy\u2010taking sessions. Factors affecting these effects included age, gender, extent of MDMA use and concomitant use of cocaine or amphetamine. The long\u2010term effects most frequently reported included the development of tolerance to MDMA (59%), impaired ability to concentrate (38%), depression (37%) and \u2018feeling more open towards people\u2019 (31%). In terms of what might persuade users to stop using MDMA, their most prominent concern was the drug's long\u2010term effects on mental health. Copyright \u00a9 2003 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/hup.529","type":"journal-article","created":{"date-parts":[[2003,10,3]],"date-time":"2003-10-03T07:01:10Z","timestamp":1065164470000},"page":"507-517","source":"Crossref","is-referenced-by-count":122,"title":["Acute, sub\u2010acute and long\u2010term subjective consequences of \u2018ecstasy\u2019 (MDMA) consumption in 430 regular users"],"prefix":"10.1002","volume":"18","author":[{"given":"Suzanne L.","family":"Verheyden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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