{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T08:48:09Z","timestamp":1792399689912,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Human Psychopharmacology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Non\u2010steroidal anti\u2010inflammatory drugs (NSAIDs) and paracetamol are among the most commonly used medications worldwide. It has been suggested that the misuse of such medications is not uncommon. The objective of the present research was to explore prevalence, reported reasons and psychopathological concomitants related to NSAIDs\/paracetamol misuse in a sample of users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The sample was made of 346 NSAIDs or paracetamol users (age range: 18\u201364\u00a0years); assessments included the 4\u2010item Perceived Stress Scale (PSS\u20104), the 10\u2010item version of the Adverse Childhood Experiences International Questionnaire (ACE\u2010IQ\u201010), the Body Image Concern Inventory (BICI), the Alcohol Use Disorders Identification Test\u2010C (AUDIT\u2010C), and questions related to NSAIDs\/paracetamol misuse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010eight individuals (13.9%) were categorized as NSAIDs\/paracetamol misusers. A logistic regression model showed that higher scores in AUDIT\u2010C, BICI and ACE\u2010IQ\u201010, and the use of psychiatric medications, were significantly associated with the likelihood of NSAIDs\/paracetamol misuse. Specific reasons related to the misuse are also reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Our findings provide novel insights into the relationship between NSAIDs\/paracetamol misuse and psychopathology, with potential clinical implications for prevention and treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/hup.70043","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T13:27:13Z","timestamp":1776950833000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Psychopathological Concomitants and Motivations Related to Misuse of Non\u2010Steroidal Anti\u2010Inflammatory Drugs and Paracetamol"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7555-8020","authenticated-orcid":false,"given":"Francesco Saverio","family":"Bersani","sequence":"first","affiliation":[{"name":"Department of Medico\u2010Surgical Sciences and Biotechnologies Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Prevete","sequence":"additional","affiliation":[{"name":"Department of Medico\u2010Surgical Sciences and Biotechnologies Sapienza University of Rome  Rome Italy"},{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3092-6475","authenticated-orcid":false,"given":"Tommaso","family":"Accinni","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Montaldo","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Pinucci","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2390-4494","authenticated-orcid":false,"given":"Annalisa","family":"Maraone","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Tarsitani","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3959-8137","authenticated-orcid":false,"given":"Massimo","family":"Pasquini","sequence":"additional","affiliation":[{"name":"Department of Human Neurosciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Imperatori","sequence":"additional","affiliation":[{"name":"Department of Health and Life Sciences European University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000542392"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40545\u2010021\u201000350\u20107"},{"issue":"105","key":"e_1_2_11_4_1","first-page":"3182","article-title":"Prevalence and Pattern of Analgesic Misuse Among Patients Attending Primary Health Care Centre in Makkah, Saudi Arabia","volume":"24","author":"Alharbi A.","year":"2020","journal-title":"Medical Science"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association.2013.Other (or Unknown) Substance\u2010Related Disorders Diagnostic and Statistical Manual of Mental Disorders.5th ed. 563\u2013686.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_11_6_1","volume-title":"The Alcohol Use Disorders Identification Test Guidelines for Use in Primary Care","author":"Babor T. 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