{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:28:02Z","timestamp":1791948482301,"version":"4.3.4"},"reference-count":70,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Inflammatory Bowel Diseases"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1002\/ibd.21417","type":"journal-article","created":{"date-parts":[[2010,8,19]],"date-time":"2010-08-19T23:31:38Z","timestamp":1282260698000},"page":"471-478","source":"Crossref","is-referenced-by-count":207,"title":["Long-term complications, extraintestinal manifestations, and mortality in adult Crohn\u02bcs disease in population-based cohorts"],"prefix":"10.1093","volume":"17","author":[{"given":"Laurent","family":"Peyrin-Biroulet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward V.","family":"Loftus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Frederic","family":"Colombel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Sandborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"R1-52-20140212","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/ajg.2009.579","volume":"105","author":"PeyrinBiroulet","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"R2-52-20140212","doi-asserted-by":"crossref","first-page":"795","DOI":"10.7326\/0003-4819-133-10-200011210-00012","volume":"133","author":"Bernstein","year":"2000","journal-title":"Ann Intern Med"},{"key":"R3-52-20140212","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1053\/gast.2002.34779","volume":"123","author":"Loftus EVJr, C Crowson","year":"2002","journal-title":"Gastroenterology"},{"key":"R4-52-20140212","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.2003.026799","volume":"53","author":"Card","year":"2004","journal-title":"Gut"},{"key":"R5-52-20140212","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s11914-996-0031-4","volume":"4","author":"Bernstein","year":"2006","journal-title":"Curr Osteoporos Rep"},{"key":"R6-52-20140212","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1111\/j.1572-0241.2003.07415.x","volume":"98","author":"Bernstein","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"R7-52-20140212","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1111\/j.1572-0241.2007.01753.x","volume":"103","author":"Leslie","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"R8-52-20140212","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/ibd.20541","volume":"15","author":"Leslie","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"R9-52-20140212","first-page":"47","volume":"43-","author":"Schoon","year":"2000","journal-title":"Scand J Gastroenterol Suppl"},{"key":"R10-52-20140212","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1053\/gast.2000.19280","volume":"119","author":"Schoon","year":"2000","journal-title":"Gastroenterology"},{"key":"R11-52-20140212","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1111\/j.1572-0241.2003.07590.x","volume":"98","author":"Bernstein","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"R12-52-20140212","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(07)61342-7","volume":"370","author":"Tang","year":"2007","journal-title":"Lancet"},{"key":"R13-52-20140212","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cgh.2007.09.016","volume":"6","author":"Bernstein","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"R14-52-20140212","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1055\/s-0037-1615600","volume":"85","author":"Bernstein","year":"2001","journal-title":"Thromb Haemost"},{"key":"R15-52-20140212","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1572-0241.2006.00974.x","volume":"102","author":"Bernstein","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"R16-52-20140212","doi-asserted-by":"crossref","first-page":"802","DOI":"10.4065\/75.8.802","volume":"75","author":"Kimura","year":"2000","journal-title":"Mayo Clin Proc"},{"key":"R17-52-20140212","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1053\/j.gastro.2005.06.022","volume":"129","author":"Gupta","year":"2005","journal-title":"Gastroenterology"},{"key":"R18-52-20140212","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/j.1572-0241.2001.03756.x","volume":"96","author":"Bernstein","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"R19-52-20140212","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1053\/j.gastro.2005.06.021","volume":"129","author":"Bernstein","year":"2005","journal-title":"Gastroenterology"},{"key":"R20-52-20140212","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1111\/j.1572-0241.2007.01215.x","volume":"102","author":"Weng","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"R21-52-20140212","first-page":"A2181","volume":"179","author":"Fenta","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"R23-52-20140212","doi-asserted-by":"crossref","first-page":"A493","DOI":"10.1111\/j.1398-9995.2008.01898.x","volume":"64","author":"Ordonez","year":"2009","journal-title":"Allergy"},{"key":"R24-52-20140212","first-page":"511","volume":"29","author":"Palm","year":"2002","journal-title":"J Rheumatol"},{"key":"R25-52-20140212","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1365-2036.2006.02720.x","volume":"23","author":"West","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"R26-52-20140212","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1053\/j.gastro.2004.03.016","volume":"126","author":"Van Staa","year":"2004","journal-title":"Gastroenterology"},{"key":"R27-52-20140212","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.cgh.2006.09.019","volume":"4","author":"Gupta","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"R28-52-20140212","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1097\/00054725-200608000-00001","volume":"12","author":"Jess","year":"2006","journal-title":"Inflamm Bowel Dis"},{"key":"R29-52-20140212","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000104731","volume":"75","author":"Katsanos","year":"2007","journal-title":"Digestion"},{"key":"R30-52-20140212","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1111\/j.1572-0241.2005.00287.x","volume":"100","author":"Jess","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"R31-52-20140212","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/j.1365-2036.2006.02854.x","volume":"23","author":"Canavan","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"R32-52-20140212","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s10350-006-0848-z","volume":"50","author":"von Roon","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"R33-52-20140212","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1053\/j.gastro.2005.12.037","volume":"130","author":"Jess","year":"2006","journal-title":"Gastroenterology"},{"key":"R34-52-20140212","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1002\/1097-0142(19910401)67:7<2015::AID-CNCR2820670731>3.0.CO;2-R","volume":"67","author":"Ekbom","year":"1991","journal-title":"Cancer"},{"key":"R35-52-20140212","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/1097-0142(20010215)91:4<854::AID-CNCR1073>3.0.CO;2-Z","volume":"91","author":"Bernstein","year":"2001","journal-title":"Cancer"},{"key":"R36-52-20140212","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3109\/00365528909093058","volume":"24","author":"Fireman","year":"1989","journal-title":"Scand J Gastroenterol"},{"key":"R37-52-20140212","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/0016-5085(94)90807-9","volume":"107","author":"Persson","year":"1994","journal-title":"Gastroenterology"},{"key":"R38-52-20140212","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1365-2036.2004.01858.x","volume":"19","author":"Jess","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"R39-52-20140212","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/annonc\/mdn595","volume":"20","author":"Hemminki","year":"2009","journal-title":"Ann Oncol"},{"key":"R40-52-20140212","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1053\/j.gastro.2009.01.064","volume":"136","author":"Soderlund","year":"2009","journal-title":"Gastroenterology"},{"key":"R41-52-20140212","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1002\/ibd.20211","volume":"13","author":"Jones","year":"2007","journal-title":"Inflamm Bowel Dis"},{"key":"R42-52-20140212","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1111\/j.1572-0241.2000.02316.x","volume":"95","author":"Loftus EVJr, T Tremaine","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"R43-52-20140212","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1053\/gast.2001.28703","volume":"121","author":"Lewis","year":"2001","journal-title":"Gastroenterology"},{"key":"R44-52-20140212","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1053\/gast.2000.16487","volume":"119","author":"Palli","year":"2000","journal-title":"Gastroenterology"},{"key":"R45-52-20140212","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1136\/gut.2004.051771","volume":"54","author":"Askling","year":"2005","journal-title":"Gut"},{"key":"R46-52-20140212","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1136\/gut.2009.181982","volume":"58","author":"Sokol","year":"2009","journal-title":"Gut"},{"key":"R48-52-20140212","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1053\/j.gastro.2008.10.021","volume":"136","author":"Singh","year":"2009","journal-title":"Gastroenterology"},{"key":"R49-52-20140212","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1572-0241.2007.01582.x","volume":"103","author":"Kane","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"R50-52-20140212","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1365-2036.2008.03766.x","volume":"28","author":"Hutfless","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"R51-52-20140212","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0016-5085(81)90719-8","volume":"80","author":"Prior","year":"1981","journal-title":"Gastroenterology"},{"key":"R52-52-20140212","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1056\/NEJM197311222892101","volume":"289","author":"Weedon","year":"1973","journal-title":"N Engl J Med"},{"key":"R53-52-20140212","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1136\/gut.31.12.1387","volume":"31","author":"Weterman","year":"1990","journal-title":"Gut"},{"key":"R54-52-20140212","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/0016-5085(92)90029-X","volume":"103","author":"Ekbom","year":"1992","journal-title":"Gastroenterology"},{"key":"R55-52-20140212","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1053\/gast.1996.v110.pm8613037","volume":"110","author":"Persson","year":"1996","journal-title":"Gastroenterology"},{"key":"R56-52-20140212","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1053\/gast.2002.33632","volume":"122","author":"Jess","year":"2002","journal-title":"Gastroenterology"},{"key":"R57-52-20140212","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/S0016-5085(98)70421-4","volume":"114","author":"Loftus EVJr, S Silverstein","year":"1998","journal-title":"Gastroenterology"},{"key":"R58-52-20140212","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1136\/gut.42.2.175","volume":"42","author":"Palli","year":"1998","journal-title":"Gut"},{"key":"R59-52-20140212","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1572-0241.2001.03466.x","volume":"96","author":"Farrokhyar","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"R60-52-20140212","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1136\/gut.33.9.1226","volume":"33","author":"Probert","year":"1992","journal-title":"Gut"},{"key":"R61-52-20140212","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3109\/00365529609006413","volume":"31","author":"Cottone","year":"1996","journal-title":"Scand J Gastroenterol"},{"key":"R62-52-20140212","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1365-2036.2007.03276.x","volume":"25","author":"Canavan","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"R63-52-20140212","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2036.2007.03276.x","volume":"25","author":"Canavan","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"R64-52-20140212","first-page":"54","volume":"46-","author":"Wolters","year":"2006","journal-title":"Scand J Gastroenterol Suppl"},{"key":"R65-52-20140212","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1136\/gut.2005.079350","volume":"55","author":"Jess","year":"2006","journal-title":"Gut"},{"key":"R66-52-20140212","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1053\/j.gastro.2007.09.022","volume":"133","author":"Hutfless","year":"2007","journal-title":"Gastroenterology"},{"key":"R67-52-20140212","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1053\/j.gastro.2003.09.029","volume":"125","author":"Card","year":"2003","journal-title":"Gastroenterology"},{"key":"R69-52-20140212","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/ibd.21007","volume":"16","author":"Duricova","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"R70-52-20140212","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1053\/j.gastro.2003.10.020","volume":"125","author":"","year":"2003","journal-title":"Gastroenterology"},{"key":"R71-52-20140212","first-page":"560","volume":"118","author":"Popivanova","year":"2008","journal-title":"J Clin Invest"},{"key":"R72-52-20140212","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.cgh.2006.03.002","volume":"4","author":"Lichtenstein","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"R73-52-20140212","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.cgh.2008.03.014","volume":"6","author":"PeyrinBiroulet","year":"2008","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Inflammatory Bowel Diseases"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T23:51:55Z","timestamp":1559433115000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ibdjournal\/article\/17\/1\/471-478\/4631202"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":70,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1002\/ibd.21417","relation":{},"ISSN":["1078-0998"],"issn-type":[{"value":"1078-0998","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}